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Crystal structure of HCV NS5b 1b with (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyrimidine derivative
分子名称:	GLYCEROL, N-{3-[5-hydroxy-8-(3-methylbutyl)-7-oxo-7,8-dihydroimidazo[1,2-a]pyrimidin-6-yl]-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase
著者	Wang, G, Lei, H, Wang, X, Das, D, Mackinnon, C, Montalbetti, C.A.G, Mears, R, Gai, X, Bailey, S, Ruhrmund, D, Hooi, L, Misialek, S, Rajagopalan, R, Cheng, R.K.Y, Barker, J.L, Felicetti, B, Stoycheva, A, Buckman, B, Kossen, K, Seiwert, S, Beigelmana, L.
登録日	2009-04-30
公開日	2009-10-13
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives. Bioorg.Med.Chem.Lett., 19, 2009

X-ray crystal structure of NS3 Helicase from HCV with a bound inhibitor at 2.42 A resolution
分子名称:	NS3, {6-(3,5-diaminophenyl)-1-[4-(propan-2-yl)benzyl]-1H-indol-3-yl}acetic acid
著者	Davies, D.R, Kim, H, Lorimer, D.
登録日	2014-11-14
公開日	2015-12-23
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.42 Å)
主引用文献	crystal structure of NS3 Helicase from HCV with a bound inhibitor TO BE PUBLISHED

X-ray crystal structure of NS3 Helicase from HCV with a bound fragment inhibitor at 2.08 A resolution
分子名称:	(1-methyl-1H-indol-3-yl)acetic acid, CHLORIDE ION, NS3-4 protease, ...
著者	Davies, D.R.
登録日	2014-11-14
公開日	2015-12-23
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.08 Å)
主引用文献	crystal structure of NS3 Helicase from HCV with a bound fragment inhibitor TO BE PUBLISHED