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CDK8/CYCC IN COMPLEX WITH COMPOUND 20
Descriptor:	CHLORIDE ION, Cyclin-C, Cyclin-dependent kinase 8, ...
Authors:	Kiefer, J.R, Schneider, E.V, Maskos, K, Bergeron, P, Koehler, M.
Deposit date:	2016-01-28
Release date:	2016-04-20
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.39 Å)
Cite:	Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8. Acs Med.Chem.Lett., 7, 2016

Crystal structure of XIAP BIR3 with CS3
Descriptor:	(3S)-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-3-methyl-N-(2-pyrimidin-2-ylphenyl)-L-prolinamide, Baculoviral IAP repeat-containing protein 4, ZINC ION
Authors:	Hymowitz, S.G.
Deposit date:	2009-05-26
Release date:	2009-06-16
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. Acs Chem.Biol., 4, 2009