6S3W
 
 | | Solution NMR Structure of TolAIII Bound to a Peptide Derived from the N-terminus of TolB | | Descriptor: | Cell envelope integrity/translocation protein TolA, TolBp | | Authors: | Kleanthous, C, Redfield, C, Rajasekar, K, Holmes, P. | | Deposit date: | 2019-06-26 | | Release date: | 2020-03-25 | | Last modified: | 2024-07-03 | | Method: | SOLUTION NMR | | Cite: | The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism.
Nat Commun, 11, 2020
|
|
1V13
 | |
8ODT
 | | Structure of TolQR complex from E.coli | | Descriptor: | Tol-Pal system protein TolQ, Tol-Pal system protein TolR | | Authors: | Webby, M.N, Kleanthous, C, Press, C.E. | | Deposit date: | 2023-03-09 | | Release date: | 2023-11-01 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Tunable force transduction through the Escherichia coli cell envelope.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6THK
 | |
4V5K
 | | Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | | Authors: | Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V. | | Deposit date: | 2010-05-29 | | Release date: | 2014-07-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
|
|
1IMP
 | | COLICIN E9 IMMUNITY PROTEIN IM9, NMR, 21 STRUCTURES | | Descriptor: | IM9 | | Authors: | Osborne, M.J, Breeze, A.L, Lian, L.-Y, Reilly, A, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 1996-05-30 | | Release date: | 1997-09-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9.
Biochemistry, 35, 1996
|
|
1IMQ
 | | COLICIN E9 IMMUNITY PROTEIN IM9, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | IM9 | | Authors: | Osborne, M.J, Breeze, A.L, Lian, L.Y, Reilly, A, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 1996-05-30 | | Release date: | 1997-07-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9.
Biochemistry, 35, 1996
|
|
1V14
 | |
1V15
 | |
4UHP
 | | Crystal structure of the pyocin AP41 DNase-Immunity complex | | Descriptor: | BACTERIOCIN IMMUNITY PROTEIN, LARGE COMPONENT OF PYOCIN AP41 | | Authors: | Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C. | | Deposit date: | 2015-03-25 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa
J.Mol.Biol., 427, 2015
|
|
4UHQ
 | | Crystal structure of the pyocin AP41 DNase | | Descriptor: | CITRIC ACID, LARGE COMPONENT OF PYOCIN AP41, NICKEL (II) ION | | Authors: | Joshi, A, Chen, S, Wojdyla, J.A, Kaminska, R, Kleanthous, C. | | Deposit date: | 2015-03-25 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structures of the Ultra-High Affinity Protein-Protein Complexes of Pyocins S2 and Ap41 and Their Cognate Immunity Proteins from Pseudomonas Aeruginosa
J.Mol.Biol., 427, 2015
|
|
4UDM
 | |
3O0E
 | | Crystal structure of OmpF in complex with colicin peptide OBS1 | | Descriptor: | Colicin-E9, Porin OmpF, octyl beta-D-glucopyranoside | | Authors: | Wojdyla, J.A, Housden, N.G, Korczynska, J, Grishkovskaya, I, Kirkpatrick, N, Brzozowski, A.M, Kleanthous, C. | | Deposit date: | 2010-07-19 | | Release date: | 2010-12-08 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
4JML
 | |
5ODW
 | | Structure of the FpvAI-pyocin S2 complex | | Descriptor: | Ferripyoverdine receptor, Pyocin-S2, SULFATE ION | | Authors: | White, P, Joshi, A, Kleanthous, C. | | Deposit date: | 2017-07-06 | | Release date: | 2017-11-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Exploitation of an iron transporter for bacterial protein antibiotic import.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4QAY
 | |
3U43
 | |
5BY4
 | |
1FSJ
 | | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN | | Descriptor: | COLICIN E9, PHOSPHATE ION, ZINC ION | | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.R, James, R, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2000-09-11 | | Release date: | 2003-06-17 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the E9 DNase domain in comparison with the inhibited structure of the E9 DNase/Im9 complex
To be Published
|
|
1FR2
 | | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A) | | Descriptor: | COLICIN E9, COLICIN E9 IMMUNITY PROTEIN, PHOSPHATE ION, ... | | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2000-09-07 | | Release date: | 2003-06-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A)
To be Published
|
|
7NST
 | | ColicinE9 partial translocation complex | | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB | | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | | Deposit date: | 2021-03-08 | | Release date: | 2021-08-11 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
|
|
7NSU
 | | ColicinE9 intact translocation complex | | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB, ... | | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | | Deposit date: | 2021-03-08 | | Release date: | 2021-08-11 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF.
Embo J., 40, 2021
|
|
5FRH
 | | Solution structure of oxidised RsrA | | Descriptor: | ANTI-SIGMA FACTOR RSRA | | Authors: | Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C. | | Deposit date: | 2015-12-17 | | Release date: | 2016-08-03 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
|
|
5FRF
 | | Solution structure of reduced and zinc-bound RsrA | | Descriptor: | ANTI-SIGMA FACTOR RSRA, ZINC ION | | Authors: | Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C. | | Deposit date: | 2015-12-17 | | Release date: | 2016-08-03 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
|
|
7NG8
 | |
