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Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide
Descriptor:	3-CHLORO-4-(2-METHYLAMINO-IMIDAZOL-1-YLMETHYL)-THIOPHENE-2-CARBOXYLIC ACID [4-CHLORO-2-(5-CHLORO-PYRIDIN-2-YLCARBAMOYL)-6-METHOXY-PHENYL]-AMIDE, CALCIUM ION, CHLORIDE ION, ...
Authors:	Adler, M, Whitlow, M.
Deposit date:	2007-03-09
Release date:	2008-01-22
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Thiophene-anthranilamides as highly potent and orally available factor xa inhibitors. J.Med.Chem., 50, 2007

RA-DOMAIN OF RAL GUANOSINE-NUCLEOTIDE DISSOCIATION STIMULATOR
Descriptor:	PROTEIN (RA-DOMAIN OF RAL GUANOSINE DISSOCIATION STIMULATOR)
Authors:	Mueller, T.D, Handel, L, Schmieder, P, Oschkinat, H.
Deposit date:	1999-03-13
Release date:	1999-03-19
Last modified:	2023-12-27
Method:	SOLUTION NMR
Cite:	High-Resolution Structure of the Ra-Domain of Human Ralgds and a Dynamics Study of its Binding Loop to Ras To be Published

Crystal Structure of 3-chloro-N-[4-chloro-2-[[(5-chloro-2-pyridinyl)amino]carbonyl]-6-methoxyphenyl]-4-[[(4,5-dihydro-2-oxazolyl)methylamino]methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa
Descriptor:	3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ...
Authors:	Adler, M, Whitlow, M.
Deposit date:	2002-09-13
Release date:	2003-01-28
Last modified:	2017-10-11
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa Biochemistry, 41, 2002

Crystal Structure of 3-chloro-N-[4-chloro-2-[[(4-chlorophenyl)amino]carbonyl]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa
Descriptor:	3-CHLORO-N-[4-CHLORO-2-[[(4-CHLOROPHENYL)AMINO]CARBONYL]PHENYL]-4-[(4-METHYL-1-PIPERAZINYL)METHYL]-2-THIOPHENECARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ...
Authors:	Adler, M, Whitlow, M.
Deposit date:	2002-09-13
Release date:	2003-01-28
Last modified:	2017-10-11
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa Biochemistry, 41, 2002