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1EJ5
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SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP
分子名称: WISKOTT-ALDRICH SYNDROME PROTEIN
著者Kim, A.S, Kakalis, L.T, Abdul-Manan, N, Liu, G.A, Rosen, M.K.
登録日2000-02-29
公開日2000-04-05
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
Nature, 404, 2000
6ORT
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BU of 6ort by Molmil
Crystal Structure of Bos taurus Mxra8 Ectodomain
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8
著者Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-04-30
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.
Cell Host Microbe, 27, 2020
1T84
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Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
分子名称: (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein
著者Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K.
登録日2004-05-11
公開日2004-07-13
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
6MX4
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CryoEM structure of chimeric Eastern Equine Encephalitis Virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid, ...
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-30
公開日2018-12-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWC
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CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody
分子名称: E1, E2, EEEV-5 antibody heavy chain, ...
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-29
公開日2018-12-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6NK3
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Crystal structure of murine Mxra8 ectodomain
分子名称: Matrix remodeling-associated protein 8
著者Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK7
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Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.99 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
6NK6
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Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-01-04
公開日2019-05-22
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.
Cell, 177, 2019
7CW3
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Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex)
分子名称: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
著者Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
登録日2020-08-27
公開日2020-11-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CW0
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Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
分子名称: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
著者Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
登録日2020-08-27
公開日2020-11-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CW2
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Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex)
分子名称: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
著者Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
登録日2020-08-27
公開日2020-11-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CVZ
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BU of 7cvz by Molmil
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263
分子名称: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
著者Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
登録日2020-08-27
公開日2020-11-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
7CVY
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Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
分子名称: Capsid protein, E1 glycoprotein, E2 glycoprotein, ...
著者Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M.
登録日2020-08-27
公開日2020-11-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
6MW9
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BU of 6mw9 by Molmil
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody
分子名称: E1, E2, EEEV-3 antibody heavy chain, ...
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-29
公開日2018-12-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWX
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CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody
分子名称: E1, E2, EEEV-69 antibody heavy chain, ...
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-30
公開日2018-12-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MUI
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CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
分子名称: E1, E2, EEEV-42 antibody heavy chain, ...
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-23
公開日2018-12-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MX7
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CryoEM structure of chimeric Eastern Equine Encephalitis Virus: Genome-Binding Capsid N-terminal Domain
分子名称: Capsid
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-30
公開日2018-12-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
6MWV
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CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-58 Antibody
分子名称: E1, E2, EEEV-58 antibody heavy chain, ...
著者Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G.
登録日2018-10-30
公開日2018-12-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.
Cell Rep, 25, 2018
8SQN
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CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
著者Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-05-04
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Cell, 186, 2023
6CRJ
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Mouse norovirus model using the crystal structure of MNV P domain and the Norwalkvirus shell domain
分子名称: Norwalk virus, MNV-1 capsid protein chimera
著者Smith, T.J.
登録日2018-03-19
公開日2018-04-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6XO4
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CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP
分子名称: Togavirin
著者Binshtein, E, Crowe, J.E.
登録日2020-07-06
公開日2020-12-23
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6XOB
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CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
分子名称: EEEV-143 Fab heavy chain, EEEV-143 Fab light chain, Togavirin
著者Binshtein, E, Crowe, J.E.
登録日2020-07-06
公開日2020-12-23
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Cell, 183, 2020
6E47
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Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Glycochenodeoxycholic Acid
分子名称: 1,2-ETHANEDIOL, CMRF35-like molecule 1, GLYCOCHENODEOXYCHOLIC ACID, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-07-16
公開日2018-09-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E48
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Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid
分子名称: (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-07-16
公開日2018-09-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W2U
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Mayaro Virus glycoprotein E1 ectodomain and glycoportien E2 ectodomain asymmetric unit
分子名称: Spike glycoprotein E1, Spike glycoprotein E2
著者Miller, A.S, Kuhn, R.J.
登録日2020-03-08
公開日2020-10-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020

 

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