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Processed Aspartate Decarboxylase Mutant with Ser25 mutated to Cys
分子名称:	Aspartate 1-decarboxylase alfa chain, Aspartate 1-decarboxylase beta chain, SULFATE ION
著者	Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
登録日	2003-07-09
公開日	2003-11-18
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural Constraints on protein self-processing in L-aspartate-alpha-decarboxylase Embo J., 22, 2003

1PQE

S25A mutant of pyruvoyl dependent aspartate decarboxylase
分子名称:	Aspartate 1-decarboxylase
著者	Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
登録日	2003-06-18
公開日	2003-11-18
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase Embo J., 22, 2003

1PT0

Unprocessed Pyruvoyl Dependent Aspartate Decarboxylase with an Alanine insertion at position 26
分子名称:	Aspartate 1-decarboxylase, SULFATE ION
著者	Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
登録日	2003-06-22
公開日	2003-11-11
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase Embo J., 22, 2003

1PT1

Unprocessed Pyruvoyl Dependent Aspartate Decarboxylase with Histidine 11 Mutated to Alanine
分子名称:	Aspartate 1-decarboxylase, SULFATE ION
著者	Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
登録日	2003-06-22
公開日	2003-11-11
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase Embo J., 22, 2003

1PQH

Serine 25 to Threonine mutation of aspartate decarboxylase
分子名称:	Aspartate 1-decarboxylase, MALONIC ACID, SODIUM ION
著者	Schmitzberger, F, Kilkenny, M.L, Lobley, C.M.C, Webb, M.E, Vinkovic, M, Matak-Vinkovic, D, Witty, M, Chirgadze, D.Y, Smith, A.G, Abell, C, Blundell, T.L.
登録日	2003-06-18
公開日	2003-11-18
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (1.29 Å)
主引用文献	Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase Embo J., 22, 2003

5OGS

Crystal structure of human AND-1 SepB domain
分子名称:	MALONATE ION, WD repeat and HMG-box DNA-binding protein 1
著者	Pellegrini, L, Simon, A.C.
登録日	2017-07-13
公開日	2017-11-29
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.503 Å)
主引用文献	The human CTF4-orthologue AND-1 interacts with DNA polymerase alpha /primase via its unique C-terminal HMG box. Open Biol, 7, 2017

5HOI

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
分子名称:	DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
著者	Simon, A.C, Pellegrini, L.
登録日	2016-01-19
公開日	2016-06-22
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase. Mol.Cell, 63, 2016

5HOG

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
分子名称:	DNA polymerase alpha-binding protein, Dna2p
著者	Simon, A.C, Pellegrini, L.
登録日	2016-01-19
公開日	2016-06-22
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (3.092 Å)
主引用文献	Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase. Mol.Cell, 63, 2016

6T9Q

Crystal structure of the second, C-terminal repeat of the DNA-binding domain of human TImeless
分子名称:	Protein timeless homolog
著者	Pellegrini, L, Holzer, S.
登録日	2019-10-28
公開日	2020-07-01
最終更新日	2024-05-15
実験手法	X-RAY DIFFRACTION (1.15 Å)
主引用文献	Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication. Embo J., 39, 2020

8QJ7

Cryo-EM structure of human DNA polymerase alpha-primase in pre-initiation stage 1
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者	Yin, Z, Pellegrini, L.
登録日	2023-09-12
公開日	2024-02-21
最終更新日	2024-05-01
実験手法	ELECTRON MICROSCOPY (3.07 Å)
主引用文献	CryoEM insights into RNA primer synthesis by the human primosome. Febs J., 291, 2024

5OFN

Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
分子名称:	DNA primase large subunit PriL,PriL-X fusion protein, DNA primase small subunit PriS, ZINC ION
著者	Pellegrini, L, Holzer, S.
登録日	2017-07-11
公開日	2017-11-29
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (3.005 Å)
主引用文献	Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster. Nat Commun, 8, 2017

5OF3

Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
分子名称:	DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA primase large subunit PriL, DNA primase small subunit PriS, ...
著者	Pellegrini, L, Holzer, S.
登録日	2017-07-10
公開日	2017-11-29
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.906 Å)
主引用文献	Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster. Nat Commun, 8, 2017

4C8H

Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein.
分子名称:	CTF4
著者	Simon, A.C, Pellegrini, L.
登録日	2013-10-01
公開日	2014-04-30
最終更新日	2014-06-18
実験手法	X-RAY DIFFRACTION (2.691 Å)
主引用文献	A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome Nature, 510, 2014

4C8S

Crystal structure of the C-terminal region of yeast Ctf4
分子名称:	DNA POLYMERASE ALPHA-BINDING PROTEIN
著者	Simon, A.C, Pellegrini, L.
登録日	2013-10-01
公開日	2014-04-30
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome Nature, 510, 2014

4C95

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5
分子名称:	DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5
著者	Simon, A.C, Pellegrini, L.
登録日	2013-10-02
公開日	2014-04-30
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.694 Å)
主引用文献	A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome Nature, 510, 2014

4C93

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.
分子名称:	DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN
著者	Simon, A.C, Pellegrini, L.
登録日	2013-10-02
公開日	2014-04-30
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.694 Å)
主引用文献	A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome Nature, 510, 2014

4FYD

Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA and dGTP
分子名称:	2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(TPGPAPGPCPGPTPGTPGPTPAPCPCPCPCPTPGPCPCPCPGPCPCP*G)-3'), DNA polymerase alpha catalytic subunit A, ...
著者	Perera, R.L, Pellegrini, L.
登録日	2012-07-04
公開日	2013-02-27
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha eLife, 2, 2013

4FVM

Crystal structure of yeast DNA polymerase alpha
分子名称:	DNA polymerase alpha catalytic subunit A
著者	Perera, R.L, Pellegrini, L.
登録日	2012-06-29
公開日	2013-02-27
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha eLife, 2, 2013

2C45

NATIVE PRECURSOR OF PYRUVOYL DEPENDENT ASPARTATE DECARBOXYLASE
分子名称:	Aspartate 1-decarboxylase
著者	Gopalan, G, Chopra, S, Ranganathan, A, Swaminathan, K.
登録日	2005-10-15
公開日	2007-03-06
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.99 Å)
主引用文献	Crystal structure of uncleaved L-aspartate-alpha-decarboxylase from Mycobacterium tuberculosis. Proteins, 65, 2006

5NXQ

Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP
分子名称:	DNA polymerase alpha-binding protein, GLYCEROL, MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU
著者	Wu, Y, Pellegrini, L.
登録日	2017-05-10
公開日	2017-08-30
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.413 Å)
主引用文献	Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design. Angew. Chem. Int. Ed. Engl., 56, 2017

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表示件数:	20
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