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5AHA
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BU of 5aha by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aR)-4-(2-methoxyethoxy)hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[(2Z)-2-(methylimino)-2,3-dihydro-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-05
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AH7
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BU of 5ah7 by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aS)-4-chlorohexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-05
Release date:2015-02-18
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AH8
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BU of 5ah8 by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aR)-4-(3,3,3-trifluoropropoxy)hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-05
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AH9
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BU of 5ah9 by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aR)-4-(2-methoxyethoxy)hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Enstrom, O, Unge, J.
Deposit date:2015-02-05
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AGZ
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BU of 5agz by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aR)-4-[(2-fluoroprop-2-en-1-yl)oxy]hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-04
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AHB
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BU of 5ahb by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aR)-4-[2-(methylamino)-2-oxoethoxy]hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[(2Z)-2-(methylimino)-2,3-dihydro-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-05
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AH6
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BU of 5ah6 by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aS)-4-chlorohexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[2-(methylamino)-1,3-benzoxazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-05
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5AHC
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BU of 5ahc by Molmil
Disubstituted bis-THF moieties as new P2 ligands in non-peptidal HIV- 1 Protease Inhibitors (II)
Descriptor: (3R,3aS,4R,6aR)-4-[2-(methylamino)-2-oxoethoxy]hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, PROTEASE
Authors:Hohlfeld, K, Wegner, J.K, Kesteleyn, B, Linclau, B, Unge, J.
Deposit date:2015-02-05
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Disubstituted Bis-Thf Moieties as New P2 Ligands in Non-Peptidal HIV-1 Protease Inhibitors (II).
J.Med.Chem., 58, 2015
5W6U
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BU of 5w6u by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP121068 (P2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-ARG-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2017-06-16
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.878 Å)
Cite:Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W5U
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BU of 5w5u by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141037 (P4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-MLE-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2017-06-15
Release date:2017-10-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.461 Å)
Cite:Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6T
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BU of 5w6t by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP151070 (P7)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-MLE-GLU-TYR-ZCL-GLU-TRP-LEU-SER-9WV, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2017-06-16
Release date:2017-10-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6I
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BU of 5w6i by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141046 (P3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2017-06-16
Release date:2017-10-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.104 Å)
Cite:Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W5S
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BU of 5w5s by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141019 (P5)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-LEU-GLU-TYR-ZCL-GLU-TRP-LEU-SER-BAL, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2017-06-15
Release date:2017-10-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.284 Å)
Cite:Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017
5W6R
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BU of 5w6r by Molmil
Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141099 (P6)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-9WV, ...
Authors:Wilson, I.A, Kadam, R.U.
Deposit date:2017-06-16
Release date:2017-10-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.731 Å)
Cite:Potent peptidic fusion inhibitors of influenza virus.
Science, 358, 2017

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