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2YBF
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BU of 2ybf by Molmil
Complex of Rad18 (Rad6 binding domain) with Rad6b
分子名称: BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ...
著者Hibbert, R.G, Sixma, T.K.
登録日2011-03-08
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YB6
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BU of 2yb6 by Molmil
Native human Rad6
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B
著者Hibbert, R.G, Sixma, T.K.
登録日2011-03-02
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6.
Proc.Natl.Acad.Sci.USA, 108, 2011
1T8C
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BU of 1t8c by Molmil
Structure of the C-type lectin domain of CD23
分子名称: Low affinity immunoglobulin epsilon Fc receptor
著者Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M.
登録日2004-05-12
公開日2005-07-26
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The structure of human CD23 and its interactions with IgE and CD21
J.Exp.Med., 202, 2005
1T8D
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BU of 1t8d by Molmil
Structure of the C-type lectin domain of CD23
分子名称: Low affinity immunoglobulin epsilon Fc receptor
著者Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M.
登録日2004-05-12
公開日2005-07-26
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The structure of human CD23 and its interactions with IgE and CD21
J.Exp.Med., 202, 2005
2Y43
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BU of 2y43 by Molmil
Rad18 ubiquitin ligase RING domain structure
分子名称: E3 UBIQUITIN-PROTEIN LIGASE RAD18, ZINC ION
著者Hibbert, R.G, Sixma, T.K.
登録日2011-01-04
公開日2011-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Symmetry and Asymmetry of the Ring-Ring Dimer of Rad18.
J.Mol.Biol., 410, 2011
3G73
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BU of 3g73 by Molmil
Structure of the FOXM1 DNA binding
分子名称: DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*GP*CP*CP*CP*G)-3'), DNA (5'-D(P*TP*TP*CP*GP*GP*GP*CP*TP*GP*TP*TP*TP*AP*TP*AP*AP*AP*CP*AP*AP*T)-3'), Forkhead box protein M1, ...
著者Littler, D.R, Perrakis, A, Hibbert, R.G, Medema, R.H.
登録日2009-02-09
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
Nucleic Acids Res., 2010
8BYU
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BU of 8byu by Molmil
Crystal Structure of HexaBody-CD38 Fab in complex with CD38
分子名称: 1,2-ETHANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Fab Heavy Chain, ...
著者Freier, R, Krapp, S, Hibbert, R.G.
登録日2022-12-14
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity.
Ebiomedicine, 93, 2023
2Y4W
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BU of 2y4w by Molmil
Solution structure of human ubiquitin conjugating enzyme Rad6b
分子名称: UBIQUITIN-CONJUGATING ENZYME E2 B
著者Huang, A, Hibbert, R.G, deJong, R.N, Das, D, Sixma, T.K, Boelens, R.
登録日2011-01-11
公開日2011-05-11
最終更新日2012-06-27
実験手法SOLUTION NMR
主引用文献Symmetry and Asymmetry of the Ring-Ring Dimer of Rad18
J.Mol.Biol., 410, 2011
6T3J
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BU of 6t3j by Molmil
Dual Epitope Targeting by Anti-DR5 Antibodies
分子名称: IgG1-hDR5-01-Heavy Chain, IgG1-hDR5-01-Light Chain, IgG1-hDR5-05-Heavy Chain, ...
著者Tauchert, M.J, Augustin, M, Krapp, S, Overdijk, M.B, Breij, E.C.W, Hibbert, R.G.
登録日2019-10-11
公開日2020-09-16
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism.
Mol.Cancer Ther., 19, 2020
4G96
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BU of 4g96 by Molmil
Crystal structure of calcium2+-free wild-type CD23 lectin domain
分子名称: 1,2-ETHANEDIOL, Low affinity immunoglobulin epsilon Fc receptor, SULFATE ION
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-07-23
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
4GI0
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BU of 4gi0 by Molmil
Crystal structure of CD23 lectin domain mutant E249A
分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-08-08
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
4G9A
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BU of 4g9a by Molmil
Crystal structure of calcium2+-bound wild-type CD23 lectin domain
分子名称: CALCIUM ION, GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-07-23
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
4GJ0
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BU of 4gj0 by Molmil
Crystal structure of CD23 lectin domain mutant S252A
分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor, SULFATE ION
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-08-09
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
4GK1
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BU of 4gk1 by Molmil
Crystal structure of CD23 lectin domain mutant D270A
分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor, SULFATE ION
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-08-10
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.236 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
4GKO
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BU of 4gko by Molmil
Crystal structure of the calcium2+-bound human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23
分子名称: CALCIUM ION, Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, ...
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-08-13
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
4GJX
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BU of 4gjx by Molmil
Crystal structure of CD23 lectin domain mutant D258A
分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor
著者Yuan, D, Sutton, B.J, Dhaliwal, B.
登録日2012-08-10
公開日2013-06-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E.
J.Biol.Chem., 288, 2013
6QC0
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BU of 6qc0 by Molmil
PCNA complex with Cdt2 C-terminal PIP-box peptide
分子名称: Denticleless protein homolog, Proliferating cell nuclear antigen
著者Perrakis, A.P, von Castelmur, E.
登録日2018-12-25
公開日2019-01-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018
6QCG
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BU of 6qcg by Molmil
PCNA complex with Cdt1 N-terminal PIP-box peptide
分子名称: DNA replication factor Cdt1, Proliferating cell nuclear antigen
著者Perrakis, A, von Castelmur, E.
登録日2018-12-28
公開日2019-01-23
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1.
Life Sci Alliance, 1, 2018

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件を2024-04-24に公開中

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