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Crystal structure of PDE10A in complex with ASP9436
Descriptor:	1-methyl-5-(1-methyl-3-{[4-(1-methyl-1H-benzimidazol-4-yl)phenoxy]methyl}-1H-pyrazol-4-yl)pyridin-2(1H)-one, MAGNESIUM ION, ZINC ION, ...
Authors:	Amano, Y, Honbou, K.
Deposit date:	2015-02-02
Release date:	2015-06-17
Last modified:	2024-03-20
Method:	X-RAY DIFFRACTION (2.03 Å)
Cite:	Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436 Bioorg.Med.Chem., 23, 2015

Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor
Descriptor:	2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1
Authors:	Kinoshita, T.
Deposit date:	2003-08-13
Release date:	2004-01-27
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase. Febs Lett., 556, 2004