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8OUA
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Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11f
Descriptor: 4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2,5-bis(fluoranyl)-3-methoxy-benzamide, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Bischof, L, Hartmann, M.D.
Deposit date:2023-04-22
Release date:2023-11-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.
J.Med.Chem., 66, 2023
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