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1L65
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BU of 1l65 by Molmil
TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Heinz, D, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence.
Proc.Natl.Acad.Sci.USA, 89, 1992
1L72
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BU of 1l72 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
1L42
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BU of 1l42 by Molmil
CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
Descriptor: T4 LYSOZYME
Authors:Daopin, S, Matthews, B.W.
Deposit date:1991-01-28
Release date:1991-10-15
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability.
J.Mol.Biol., 221, 1991
1L59
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BU of 1l59 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
1L70
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BU of 1l70 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
1L75
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BU of 1l75 by Molmil
MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1991-09-23
Release date:1991-10-15
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
4BPQ
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BU of 4bpq by Molmil
Structure and substrate induced conformational changes of the secondary citrate-sodium symporter CitS revealed by electron crystallography
Descriptor: CITRATE:SODIUM SYMPORTER
Authors:Kebbel, F, Kurz, M, Arheit, M, Gruetter, M.G, Stahlberg, H.
Deposit date:2013-05-27
Release date:2013-07-17
Last modified:2013-09-11
Method:ELECTRON CRYSTALLOGRAPHY (6 Å)
Cite:Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter Cits Revealed by Electron Crystallography.
Structure, 21, 2013
4DX7
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BU of 4dx7 by Molmil
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
Descriptor: Acriflavine resistance protein B, DARPIN, DECANE, ...
Authors:Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M.
Deposit date:2012-02-27
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.253 Å)
Cite:Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DX6
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BU of 4dx6 by Molmil
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
Descriptor: Acriflavine resistance protein B, DARPIN, DODECYL-BETA-D-MALTOSIDE
Authors:Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M.
Deposit date:2012-02-27
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DX5
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BU of 4dx5 by Molmil
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, DARPIN, ...
Authors:Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M.
Deposit date:2012-02-27
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.
Proc.Natl.Acad.Sci.USA, 109, 2012
3N2W
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BU of 3n2w by Molmil
Crystal structure of the N-terminal beta-aminopeptidase BapA from Sphingosinicella xenopeptidilytica
Descriptor: Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION
Authors:Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G.
Deposit date:2010-05-19
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
3N33
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BU of 3n33 by Molmil
Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with pefabloc SC (AEBSF)
Descriptor: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-peptidyl aminopeptidase, ...
Authors:Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G.
Deposit date:2010-05-19
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
3N5I
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BU of 3n5i by Molmil
Crystal structure of the precursor (S250A mutant) of the N-terminal beta-aminopeptidase BapA
Descriptor: Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION
Authors:Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G.
Deposit date:2010-05-25
Release date:2011-06-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012
3NOG
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BU of 3nog by Molmil
Designed ankyrin repeat protein (DARPin) Binders to AcrB: Plasticity of the Interface
Descriptor: Acriflavine resistance protein B, Designed ankyrin repeat protein
Authors:Monroe, N, Briand, C, Gruetter, M.G.
Deposit date:2010-06-25
Release date:2011-05-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface
J.Struct.Biol., 174, 2011
3NOC
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BU of 3noc by Molmil
Designed ankyrin repeat protein (DARPin) binders to AcrB: Plasticity of the Interface
Descriptor: Acriflavine resistance protein B, Designed ankyrin repeat protein
Authors:Monroe, N, Briand, C, Gruetter, M.G.
Deposit date:2010-06-25
Release date:2011-05-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface
J.Struct.Biol., 174, 2011
3QF4
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BU of 3qf4 by Molmil
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Descriptor: ABC transporter, ATP-binding protein, MAGNESIUM ION, ...
Authors:Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A.
Deposit date:2011-01-21
Release date:2012-03-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Nat.Struct.Mol.Biol., 19, 2012
1L10
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BU of 1l10 by Molmil
STRUCTURAL STUDIES OF MUTANTS OF THE LYSOZYME OF BACTERIOPHAGE T4. THE TEMPERATURE-SENSITIVE MUTANT PROTEIN THR157 (RIGHT ARROW) ILE
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural studies of mutants of the lysozyme of bacteriophage T4. The temperature-sensitive mutant protein Thr157----Ile.
J.Mol.Biol., 197, 1987
1L01
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BU of 1l01 by Molmil
STRUCTURAL STUDIES OF MUTANTS OF THE LYSOZYME OF BACTERIOPHAGE T4. THE TEMPERATURE-SENSITIVE MUTANT PROTEIN THR157 (RIGHT ARROW) ILE
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural studies of mutants of the lysozyme of bacteriophage T4. The temperature-sensitive mutant protein Thr157----Ile.
J.Mol.Biol., 197, 1987
1L02
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BU of 1l02 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L09
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BU of 1l09 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Bell, J, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L06
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BU of 1l06 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L15
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BU of 1l15 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L13
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BU of 1l13 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L12
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BU of 1l12 by Molmil
CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Dao-Pin, S, Alber, T, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
1L16
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BU of 1l16 by Molmil
STRUCTURAL ANALYSIS OF THE TEMPERATURE-SENSITIVE MUTANT OF BACTERIOPHAGE T4 LYSOZYME, GLYCINE 156 (RIGHT ARROW) ASPARTIC ACID
Descriptor: T4 LYSOZYME
Authors:Gray, T.M, Matthews, B.W.
Deposit date:1988-02-05
Release date:1988-04-16
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of the temperature-sensitive mutant of bacteriophage T4 lysozyme, glycine 156----aspartic acid.
J.Biol.Chem., 262, 1987

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