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4U5E
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BU of 4u5e by Molmil
Crystal structure of GluA2 T625G, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5073 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5B
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BU of 4u5b by Molmil
Crystal structure of GluA2 A622T, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-25
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5037 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
4U5F
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BU of 4u5f by Molmil
Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex, GluA2cryst2 construct
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ...
Authors:Chen, L, Gouaux, E.
Deposit date:2014-07-24
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
3QS5
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BU of 3qs5 by Molmil
Crystal structure of LeuT mutant I359Q bound to sodium and L-tryptophan
Descriptor: Na(+):neurotransmitter symporter (Snf family), SODIUM ION, TRYPTOPHAN, ...
Authors:Piscitelli, C.L, Gouaux, E.
Deposit date:2011-02-19
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into transport mechanism from LeuT engineered to transport tryptophan.
Embo J., 31, 2012
3QS6
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BU of 3qs6 by Molmil
Crystal structure of LeuT mutant F259V,I359Q bound to sodium and L-tryptophan
Descriptor: Na(+):neurotransmitter symporter (Snf family), SODIUM ION, TRYPTOPHAN, ...
Authors:Piscitelli, C.L, Gouaux, E.
Deposit date:2011-02-19
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Insights into transport mechanism from LeuT engineered to transport tryptophan.
Embo J., 31, 2012
3QS4
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BU of 3qs4 by Molmil
Crystal structure of LeuT mutant F259V bound to sodium and L-tryptophan
Descriptor: Na(+):neurotransmitter symporter (Snf family), SODIUM ION, TRYPTOPHAN, ...
Authors:Piscitelli, C.L, Gouaux, E.
Deposit date:2011-02-19
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Insights into transport mechanism from LeuT engineered to transport tryptophan.
Embo J., 31, 2012
3RHW
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BU of 3rhw by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and ivermectin
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, ...
Authors:Hibbs, R.E, Gouaux, E.
Deposit date:2011-04-12
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Principles of activation and permeation in an anion-selective Cys-loop receptor.
Nature, 474, 2011
3RIF
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BU of 3rif by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate.
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, ...
Authors:Hibbs, R.E, Gouaux, E.
Deposit date:2011-04-13
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.345 Å)
Cite:Principles of activation and permeation in an anion-selective Cys-loop receptor.
Nature, 474, 2011
3RIA
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BU of 3ria by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and iodide.
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, CHLORIDE ION, ...
Authors:Hibbs, R.E, Gouaux, E.
Deposit date:2011-04-13
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Principles of activation and permeation in an anion-selective Cys-loop receptor.
Nature, 474, 2011
3RI5
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BU of 3ri5 by Molmil
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and picrotoxin
Descriptor: (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hibbs, R.E, Gouaux, E.
Deposit date:2011-04-12
Release date:2011-05-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Principles of activation and permeation in an anion-selective Cys-loop receptor.
Nature, 474, 2011
3TT3
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BU of 3tt3 by Molmil
Crystal Structure of LeuT in the inward-open conformation in complex with Fab
Descriptor: Leucine transporter LeuT, mouse monoclonal 1gG1 Fab fragment, heavy chain, ...
Authors:Krishnamurthy, H, Gouaux, E.
Deposit date:2011-09-13
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3TU0
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BU of 3tu0 by Molmil
Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium
Descriptor: ALANINE, Leucine transporter LeuT, SODIUM ION
Authors:Krishnamurthy, H, Gouaux, E.
Deposit date:2011-09-15
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3TT1
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BU of 3tt1 by Molmil
Crystal Structure of LeuT in the outward-open conformation in complex with Fab
Descriptor: Leucine transporter LeuT, SODIUM ION, mouse monoclonal 1gG2a Fab fragment, ...
Authors:Krishnamurthy, H, Gouaux, E.
Deposit date:2011-09-13
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.099 Å)
Cite:X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
3USG
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BU of 3usg by Molmil
Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, LEUCINE, ...
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USJ
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BU of 3usj by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
Descriptor: LEUCINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USK
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BU of 3usk by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
Descriptor: LEUCINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USL
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BU of 3usl by Molmil
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles
Descriptor: ACETATE ION, IODIDE ION, PHOSPHOCHOLINE, ...
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USO
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BU of 3uso by Molmil
Crystal structure of LeuT bound to L-selenomethionine in space group P21212 from lipid bicelles
Descriptor: SELENOMETHIONINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USI
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BU of 3usi by Molmil
Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles
Descriptor: LEUCINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USP
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BU of 3usp by Molmil
Crystal structure of LeuT in heptyl-beta-D-Selenoglucoside
Descriptor: CHLORIDE ION, LEUCINE, SODIUM ION, ...
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USM
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BU of 3usm by Molmil
Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A)
Descriptor: IODIDE ION, PHOSPHOCHOLINE, SELENOMETHIONINE, ...
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.008 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
1MQH
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BU of 1mqh by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution
Descriptor: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2
Authors:Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQI
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BU of 1mqi by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Fluoro-Willardiine at 1.35 Angstroms Resolution
Descriptor: 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2
Authors:Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQJ
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BU of 1mqj by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution
Descriptor: 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2
Authors:Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003
1MQG
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BU of 1mqg by Molmil
Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Iodo-Willardiine at 2.15 Angstroms Resolution
Descriptor: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E.
Deposit date:2002-09-16
Release date:2003-08-05
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for partial agonist action at ionotropic glutamate receptors
Nat.Neurosci., 6, 2003

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數據於2024-05-22公開中

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