5IMR
| Structure of ribosome bound to cofactor at 5.7 angstrom resolution | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. | Deposit date: | 2016-03-06 | Release date: | 2016-05-18 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome J.Biol.Chem., 291, 2016
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5IMQ
| Structure of ribosome bound to cofactor at 3.8 angstrom resolution | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. | Deposit date: | 2016-03-06 | Release date: | 2016-05-18 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome J.Biol.Chem., 291, 2016
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4CXX
| Crystal structure of human FTO in complex with acylhydrazine inhibitor 16 | Descriptor: | (2E)-4-{N'-[4-(4-tert-Butyl-benzyl)-pyridine-3-carbonyl]-hydrazino}-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION | Authors: | Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. | Deposit date: | 2014-04-09 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO. Chem Sci, 6, 2015
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4CXY
| Crystal structure of human FTO in complex with acylhydrazine inhibitor 21 | Descriptor: | (E)-4-(2-Nicotinoylhydrazinyl)-4-oxobut-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION | Authors: | Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. | Deposit date: | 2014-04-09 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO. Chem Sci, 6, 2015
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4CXW
| Crystal structure of human FTO in complex with subfamily-selective inhibitor 12 | Descriptor: | (2E)-4-[N'-(4-benzyl-pyridine-3-carbonyl)-hydrazino]-4-oxo-but-2-enoic acid, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO, NICKEL (II) ION | Authors: | Toh, D.W, Sun, L, Tan, J, Chen, Y, Lau, L.Z.M, Hong, W, Woon, E.C.Y, Gao, Y.G. | Deposit date: | 2014-04-09 | Release date: | 2014-10-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO. Chem Sci, 6, 2015
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4D6V
| Crystal structure of signal transducing protein | Descriptor: | G PROTEIN BETA SUBUNIT GIB2 | Authors: | Ero, R, Dimitrova, V.T, Chen, Y, Bu, W, Feng, S, Liu, T, Wang, P, Xue, C, Tan, S.M, Gao, Y.G. | Deposit date: | 2014-11-17 | Release date: | 2015-03-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Gib2, a Signal-Transducing Protein Scaffold Associated with Ribosomes in Cryptococcus Neoformans. Sci.Rep., 5, 2015
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7WI4
| Cryo-EM structure of E.Coli FtsH protease cytosolic domains | Descriptor: | ATP-dependent zinc metalloprotease FtsH, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Qiao, Z, Gao, Y.G. | Deposit date: | 2022-01-02 | Release date: | 2022-06-01 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the entire FtsH-HflKC AAA protease complex. Cell Rep, 39, 2022
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7WI3
| Cryo-EM structure of E.Coli FtsH-HflkC AAA protease complex | Descriptor: | ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Modulator of FtsH protease HflK | Authors: | Qiao, Z, Gao, Y.G. | Deposit date: | 2022-01-02 | Release date: | 2022-06-01 | Last modified: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structure of the entire FtsH-HflKC AAA protease complex. Cell Rep, 39, 2022
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7VBS
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7VBW
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7WQ5
| Crystal structure of Arabidopsis transcriptional factor WRINKLED1 with dsDNA | Descriptor: | AMMONIUM ION, DNA (5'-D(P*GP*TP*GP*GP*AP*CP*GP*AP*TP*GP*AP*AP*AP*CP*CP*GP*AP*GP*GP*AP*AP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*TP*TP*CP*CP*TP*CP*GP*GP*TP*TP*TP*CP*AP*TP*CP*GP*TP*CP*CP*AP*C)-3'), ... | Authors: | Zhu, Q, Gao, Y.G. | Deposit date: | 2022-01-24 | Release date: | 2022-08-31 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular basis of the key regulator WRINKLED1 in plant oil biosynthesis. Sci Adv, 8, 2022
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5Y4S
| Structure of a methyltransferase complex | Descriptor: | Chemotaxis protein methyltransferase 1 | Authors: | Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. | Deposit date: | 2017-08-04 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.405 Å) | Cite: | Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein. J. Biol. Chem., 293, 2018
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5Y4R
| Structure of a methyltransferase complex | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Chemotaxis protein methyltransferase 1, Cyclic diguanosine monophosphate-binding protein PA4608, ... | Authors: | Yan, X, Xin, L, Tan, Y.J, Jin, S, Liang, Z.X, Gao, Y.G. | Deposit date: | 2017-08-04 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein. J. Biol. Chem., 293, 2018
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6ABS
| Actin interacting protein 5 (Aip5, mutant) | Descriptor: | Actin binding protein, PENTAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | Authors: | Sun, J, Ying, X, Toh, J, Hong, W, Miao, Y, Gao, Y.G. | Deposit date: | 2018-07-23 | Release date: | 2019-11-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization. Nat Commun, 10, 2019
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6ABR
| Actin interacting protein 5 (Aip5, wild type) | Descriptor: | Actin binding protein | Authors: | Sun, J, Xie, Y, Toh, J.D.W, Hong, W, MIao, Y, Gao, Y.G. | Deposit date: | 2018-07-23 | Release date: | 2019-11-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization. Nat Commun, 10, 2019
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1TTN
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4V5F
| The structure of the ribosome with elongation factor G trapped in the post-translocational state | Descriptor: | 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Gao, Y.-G, Selmer, M, Dunham, C.M, Weixlbaumer, A, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2009-09-01 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The structure of the ribosome with elongation factor G trapped in the posttranslocational state. Science, 326, 2009
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440D
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2MDJ
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1D22
| BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON | Descriptor: | DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'), U-58872, HYDROXY DERIVATIVE OF NOGALAMYCIN | Authors: | Gao, Y.-G, Liaw, Y.-C, Robinson, H, Wang, A.H.-J. | Deposit date: | 1990-08-08 | Release date: | 1991-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison. Biochemistry, 29, 1990
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1D38
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1D21
| BINDING OF THE ANTITUMOR DRUG NOGALAMYCIN AND ITS DERIVATIVES TO DNA: STRUCTURAL COMPARISON | Descriptor: | DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'), NOGALAMYCIN | Authors: | Gao, Y.-G, Liaw, Y.-C, Robinson, H, Wang, A.H.-J. | Deposit date: | 1990-08-08 | Release date: | 1991-07-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison. Biochemistry, 29, 1990
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1D37
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1D35
| FACILE FORMATION OF A CROSSLINKED ADDUCT BETWEEN DNA AND THE DAUNORUBICIN DERIVATIVE MAR70 MEDIATED BY FORMALDEHYDE: MOLECULAR STRUCTURE OF THE MAR70-D(CGTNACG) COVALENT ADDUC | Descriptor: | 4'-EPI-4'-(2-DEOXYFUCOSE)DAUNOMYCIN, DNA (5'-D(*CP*GP*TP*(A40)P*CP*G)-3'), MAGNESIUM ION | Authors: | Gao, Y.-G, Liaw, Y.-C, Li, Y.-K, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J. | Deposit date: | 1991-04-23 | Release date: | 1992-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct. Proc.Natl.Acad.Sci.USA, 88, 1991
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1D36
| FACILE FORMATION OF A CROSSLINKED ADDUCT BETWEEN DNA AND THE DAUNORUBICIN DERIVATIVE MAR70 MEDIATED BY FORMALDEHYDE: MOLECULAR STRUCTURE OF THE MAR70-D(CGTNACG) COVALENT ADDUC | Descriptor: | 4'-EPI-4'-(2-DEOXYFUCOSE)DAUNOMYCIN, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3'), MAGNESIUM ION | Authors: | Gao, Y.-G, Liaw, Y.-C, Li, Y.-K, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J. | Deposit date: | 1991-04-23 | Release date: | 1992-04-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct. Proc.Natl.Acad.Sci.USA, 88, 1991
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