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1DRZ
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BU of 1drz by Molmil
U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX
Descriptor: MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ...
Authors:Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A.
Deposit date:1998-09-01
Release date:1999-02-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
1AN2
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BU of 1an2 by Molmil
RECOGNITION BY MAX OF ITS COGNATE DNA THROUGH A DIMERIC B/HLH/Z DOMAIN
Descriptor: DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3'), PROTEIN (TRANSCRIPTION FACTOR MAX (TF MAX))
Authors:Ferre-D'Amare, A.R, Prendergast, G.C, Ziff, E.B, Burley, S.K.
Deposit date:1996-09-06
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain.
Nature, 363, 1993
1AN4
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BU of 1an4 by Molmil
STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF
Descriptor: DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR)
Authors:Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K.
Deposit date:1997-03-15
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and function of the b/HLH/Z domain of USF.
EMBO J., 13, 1994
3IWN
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BU of 3iwn by Molmil
Co-crystal structure of a bacterial c-di-GMP riboswitch
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A
Authors:Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R.
Deposit date:2009-09-02
Release date:2009-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch.
Nat.Struct.Mol.Biol., 16, 2009
4W90
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BU of 4w90 by Molmil
Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.118 Å)
Cite:Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
Embo J., 33, 2014
4TS0
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BU of 4ts0 by Molmil
Crystal structure of the Spinach RNA aptamer in complex with DFHBI, barium ions
Descriptor: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, BARIUM ION, POTASSIUM ION, ...
Authors:Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R.
Deposit date:2014-06-18
Release date:2014-07-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for activity of highly efficient RNA mimics of green fluorescent protein.
Nat.Struct.Mol.Biol., 21, 2014
1M5K
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BU of 1m5k by Molmil
Crystal structure of a hairpin ribozyme in the catalytically-active conformation
Descriptor: CALCIUM ION, CHLORIDE ION, PROTEIN (U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A), ...
Authors:Rupert, P.B, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
7SXP
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BU of 7sxp by Molmil
G-quadruplex structure formed in the NRAS mRNA with a G8U substitution
Descriptor: CACODYLIC ACID, NRAS mRNA, POTASSIUM ION
Authors:Banco, M.T, Ferre-D'Amare, A.R.
Deposit date:2021-11-24
Release date:2023-05-31
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Investigating the NRAS 5' UTR as a target for small molecules.
Cell Chem Biol, 30, 2023
8F5G
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BU of 8f5g by Molmil
NusG-RNA complex
Descriptor: DI(HYDROXYETHYL)ETHER, RNA, Transcription termination/antitermination protein NusG
Authors:Elghondakly, A.T, Ferre-D'Amare, A.R.
Deposit date:2022-11-14
Release date:2023-11-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Major-groove sequence-specific RNA recognition by LoaP, a paralog of transcription elongation factor NusG.
Structure, 32, 2024
1ZL3
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BU of 1zl3 by Molmil
Coupling of active site motions and RNA binding
Descriptor: 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA pseudouridine synthase B
Authors:Hoang, C, Hamilton, C.S, Mueller, E.G, Ferre-D'Amare, A.R.
Deposit date:2005-05-05
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain
Protein Sci., 14, 2005
4TZW
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BU of 4tzw by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and replacing Mg2+ with Sr2+ post crystallization
Descriptor: Ribosome-associated protein L7Ae-like, STRONTIUM ION, T-box Stem I, ...
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (4.671 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZP
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BU of 4tzp by Molmil
As Grown, Untreated Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its cognate tRNAGly, and B. subtilis YbxF protein
Descriptor: Ribosome-associated protein L7Ae-like, engineered tRNA, glyQ T-box Stem I
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-10
Release date:2014-09-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (8.503 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZV
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BU of 4tzv by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate post crystallization
Descriptor: Ribosome-associated protein L7Ae-like, T-box stem I, engineered tRNA
Authors:Zhang, J, Ferre-D'Amare, A.R.
Deposit date:2014-07-11
Release date:2014-09-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (5.03 Å)
Cite:Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
8VX1
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BU of 8vx1 by Molmil
Cryo-EM Structure of DHX36 bound to the cMyc DNA G-quadruplex, Class 2
Descriptor: ATP-dependent DNA/RNA helicase DHX36, DNA (27-MER)
Authors:Banco, M.T, Ferre-D'Amare, A.R.
Deposit date:2024-02-02
Release date:2025-08-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Inter-domain synergy enables both DNA and RNA G-quadruplex unwinding by the DEAH-box helicase DHX36
To Be Published
8VV2
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BU of 8vv2 by Molmil
Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 1
Descriptor: ATP-dependent DNA/RNA helicase DHX36, RNA (27-MER)
Authors:Banco, M.T, Ferre-D'Amare, A.R.
Deposit date:2024-01-30
Release date:2025-07-30
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Inter-domain synergy enables both DNA and RNA G-quadruplex unwinding by the DEAH-box helicase DHX36
To Be Published
8VVD
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BU of 8vvd by Molmil
Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 2
Descriptor: ATP-dependent DNA/RNA helicase DHX36, RNA (27-MER)
Authors:Banco, M.T, Ferre-D'Amare, A.R.
Deposit date:2024-01-30
Release date:2025-07-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Inter-domain synergy enables both DNA and RNA G-quadruplex unwinding by the DEAH-box helicase DHX36
To Be Published
9BZC
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BU of 9bzc by Molmil
Cocrystal structure of Clostridium beijerinckii ZTP riboswitch with ZMP and Cs
Descriptor: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, CESIUM ION, MAGNESIUM ION, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2024-05-24
Release date:2024-11-27
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Cocrystal structure of Clostridium beijerinckii ZTP riboswitch with ZMP and Cs
To Be Published
6PUQ
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BU of 6puq by Molmil
1.56 A crystal structure of flavodoxin-like domain of Schizosaccharomyces japonicus putative tRNAPhe 4-demethylwyosine synthase Tyw1 in complex with FMN
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ...
Authors:Sjekloca, L, Ferre-D'Amare, A.R.
Deposit date:2019-07-18
Release date:2020-07-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Biochemical and structural characterization of the flavodoxin-like domain of the Schizosaccharomyces japonicus putative tRNAPhe 4-demethylwyosine synthase Tyw1 in complex with FMN.
MicroPubl Biol, 2022, 2022
1M5V
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BU of 1m5v by Molmil
Transition State Stabilization by a Catalytic RNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, RNA HAIRPIN RIBOZYME, ...
Authors:Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5P
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BU of 1m5p by Molmil
Transition State Stabilization by a Catalytic RNA
Descriptor: CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ...
Authors:Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
1M5O
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BU of 1m5o by Molmil
Transition State Stabilization by a Catalytic RNA
Descriptor: CALCIUM ION, RNA SUBSTRATE, RNA HAIRPIN RIBOZYME, ...
Authors:Rupert, P.B, Massey, A.P, Sigurdsson, S.T, Ferre-D'Amare, A.R.
Deposit date:2002-07-09
Release date:2002-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Transition state stabilization by a catalytic RNA
Science, 298, 2002
9DIG
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BU of 9dig by Molmil
Rous sarcoma virus frameshifting pseudoknot RNA EM straight dimer
Descriptor: MAGNESIUM ION, POTASSIUM ION, frameshifting pseudoknot RNA
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2024-09-05
Release date:2025-04-09
Last modified:2025-04-16
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element.
Proc.Natl.Acad.Sci.USA, 122, 2025
9DIB
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BU of 9dib by Molmil
Rous sarcoma virus frameshifting pseudoknot RNA
Descriptor: IRIDIUM HEXAMMINE ION, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2024-09-05
Release date:2025-04-09
Last modified:2025-04-16
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element.
Proc.Natl.Acad.Sci.USA, 122, 2025
9DII
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BU of 9dii by Molmil
Rous sarcoma virus frameshifting pseudoknot RNA EM straight dimer
Descriptor: frameshifting pseudoknot RNA
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2024-09-05
Release date:2025-04-09
Last modified:2025-04-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element.
Proc.Natl.Acad.Sci.USA, 122, 2025
9DID
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BU of 9did by Molmil
Rous sarcoma virus frameshifting pseudoknot RNA
Descriptor: IRIDIUM HEXAMMINE ION, POTASSIUM ION, TRIS(HYDROXYETHYL)AMINOMETHANE, ...
Authors:Jones, C.P, Ferre-D'Amare, A.R.
Deposit date:2024-09-05
Release date:2025-04-09
Last modified:2025-04-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element.
Proc.Natl.Acad.Sci.USA, 122, 2025

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