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PPARd complexed with a phenoxyacetic acid partial agonist
分子名称:	IODIDE ION, Peroxisome proliferator-activated receptor delta, [(4-{butyl[2-methyl-4'-(methylsulfanyl)biphenyl-3-yl]sulfamoyl}naphthalen-1-yl)oxy]acetic acid, ...
著者	Lambert, M.H, Evans, K.A, Shearer, B.G, Wisnoski, D.D, Shi, D, Jin, J, Rivero, R.A, Sparks, S.M, Winegar, D.A, Billin, A.N, Britt, C, Way, J.M, Leesnitzer, L.M, Merrihew, R.V.
登録日	2010-10-27
公開日	2011-10-12
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Phenoxyacetic acid PPARd partial agonists for the treatment of type 2 diabetes: synthesis, optimization, and in vivo efficacy Bioorg.Med.Chem.Lett., 21, 2011

Crystal Structure of human phosphorylated IRE1alpha in complex with a type III kinase inhibitor (GSK2850163A)
分子名称:	(5R)-2-(3,4-dichlorobenzyl)-N-(4-methylbenzyl)-2,7-diazaspiro[4.5]decane-7-carboxamide, Serine/threonine-protein kinase/endoribonuclease IRE1
著者	Concha, N.O.
登録日	2015-03-24
公開日	2015-11-11
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.463 Å)
主引用文献	Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity. Mol.Pharmacol., 88, 2015

Crystal structure of pIRE1alpha in complex with staurosporine
分子名称:	STAUROSPORINE, Serine/threonine-protein kinase/endoribonuclease IRE1
著者	Concha, N.O.
登録日	2015-03-24
公開日	2015-11-11
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.494 Å)
主引用文献	Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity. Mol.Pharmacol., 88, 2015

Crystal Structure of human phosphorylated IRE1alpha in complex with ADP-Mg
分子名称:	ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1
著者	Concha, N.O.
登録日	2015-03-24
公開日	2015-11-11
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (3.102 Å)
主引用文献	Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity. Mol.Pharmacol., 88, 2015