9ENP
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![BU of 9enp by Molmil](/molmil-images/mine/9enp) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2024-03-13 | Release date: | 2024-05-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.12 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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9ENQ
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![BU of 9enq by Molmil](/molmil-images/mine/9enq) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site with 1-bp DNA mismatch | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2024-03-13 | Release date: | 2024-05-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.12 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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8OJ6
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![BU of 8oj6 by Molmil](/molmil-images/mine/8oj6) | HSV-1 DNA polymerase-processivity factor complex in pre-translocation state | Descriptor: | DNA (22-MER), DNA (48-MER), DNA polymerase catalytic subunit, ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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8OJ7
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![BU of 8oj7 by Molmil](/molmil-images/mine/8oj7) | HSV-1 DNA polymerase-processivity factor complex in halted elongation state | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (53-MER), DNA (67-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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8OJB
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![BU of 8ojb by Molmil](/molmil-images/mine/8ojb) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site | Descriptor: | CALCIUM ION, DNA (47-MER), DNA polymerase catalytic subunit | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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8OJC
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![BU of 8ojc by Molmil](/molmil-images/mine/8ojc) | HSV-1 DNA polymerase active site in alternative exonuclease state | Descriptor: | CALCIUM ION, DNA (47-MER), DNA polymerase catalytic subunit | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.08 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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8OJA
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![BU of 8oja by Molmil](/molmil-images/mine/8oja) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state | Descriptor: | CALCIUM ION, DNA (47-MER), DNA (68-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (1.87 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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8OJD
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![BU of 8ojd by Molmil](/molmil-images/mine/8ojd) | HSV-1 DNA polymerase beta-hairpin loop | Descriptor: | CALCIUM ION, DNA (47-MER), DNA (68-MER), ... | Authors: | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | Deposit date: | 2023-03-24 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024
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5CZX
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![BU of 5czx by Molmil](/molmil-images/mine/5czx) | Crystal structure of Notch3 NRR in complex with 20358 Fab | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 20358 Fab heavy chain, ... | Authors: | Hu, T, Fryer, C, Chopra, R, Clark, K. | Deposit date: | 2015-08-01 | Release date: | 2016-06-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies. Oncogene, 35, 2016
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5CZV
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![BU of 5czv by Molmil](/molmil-images/mine/5czv) | Crystal structure of Notch3 NRR in complex with 20350 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 20350 heavy chain, ... | Authors: | Hu, T, Fryer, C, Chopra, R, Clark, K. | Deposit date: | 2015-08-01 | Release date: | 2016-06-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies. Oncogene, 35, 2016
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