3EOA
 
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3EO9
 | | Crystal structure the Fab fragment of Efalizumab | | 分子名称: | Efalizumab Fab fragment, heavy chain, light chain | | 著者 | Li, S, Ding, J. | | 登録日 | 2008-09-26 | | 公開日 | 2009-04-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4QTJ
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4QTK
 | | Complex of WOPR domain of Wor1 in Candida albicans with the 17bp dsDNA | | 分子名称: | DNA (5'-D(*AP*AP*GP*TP*TP*AP*AP*AP*CP*TP*TP*TP*TP*TP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*AP*AP*AP*AP*AP*GP*TP*TP*TP*AP*AP*CP*TP*T)-3'), White-opaque regulator 1 | | 著者 | Zhang, S, Zhang, T, Ding, J. | | 登録日 | 2014-07-08 | | 公開日 | 2014-08-13 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Crystal structure of the WOPR-DNA complex and implications for Wor1 function in white-opaque switching of Candida albicans.
Cell Res., 24, 2014
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4HK6
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4HK7
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4HK5
 | | Crystal structure of Cordyceps militaris IDCase in apo form | | 分子名称: | Uracil-5-carboxylate decarboxylase, ZINC ION | | 著者 | Xu, S, Zhu, J, Ding, J. | | 登録日 | 2012-10-15 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4HJW
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7E1T
 | | Crystal structure of Rab9A-GTP-Nde1 | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Isoform 2 of Nuclear distribution protein nudE homolog 1, MAGNESIUM ION, ... | | 著者 | Zhang, Y, Zhang, T, Ding, J. | | 登録日 | 2021-02-03 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Nde1 is a Rab9 effector for loading late endosomes to cytoplasmic dynein motor complex.
Structure, 30, 2022
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4L44
 | | Crystal structures of human p70S6K1-T389A (form II) | | 分子名称: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... | | 著者 | Wang, J, Zhong, C, Ding, J. | | 登録日 | 2013-06-07 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
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4L46
 | | Crystal structures of human p70S6K1-WT | | 分子名称: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... | | 著者 | Wang, J, Zhong, C, Ding, J. | | 登録日 | 2013-06-07 | | 公開日 | 2013-07-24 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
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4L42
 | | Crystal structures of human p70S6K1-PIF | | 分子名称: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, SULFATE ION, ... | | 著者 | Wang, J, Zhong, C, Ding, J. | | 登録日 | 2013-06-07 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
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4LAL
 | | Crystal structure of Cordyceps militaris IDCase D323A mutant in complex with 5-carboxyl-uracil | | 分子名称: | 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, HEXAETHYLENE GLYCOL, Uracil-5-carboxylate decarboxylase, ... | | 著者 | Xu, S, Li, W, Zhu, J, Ding, J. | | 登録日 | 2013-06-20 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4L45
 | | Crystal structures of human p70S6K1-T389E | | 分子名称: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein | | 著者 | Wang, J, Zhong, C, Ding, J. | | 登録日 | 2013-06-07 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
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4LAM
 | | Crystal structure of Cordyceps militaris IDCase D323N mutant in complex with 5-carboxyl-uracil | | 分子名称: | 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, HEXAETHYLENE GLYCOL, Uracil-5-carboxylate decarboxylase, ... | | 著者 | Xu, S, Li, W, Zhu, J, Ding, J. | | 登録日 | 2013-06-20 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4L3J
 | | Crystal structures of human p70S6K1 kinase domain | | 分子名称: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein, ZINC ION | | 著者 | Wang, J, Zhong, C, Ding, J. | | 登録日 | 2013-06-06 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
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4L43
 | | Crystal structures of human p70S6K1-T389A (form I) | | 分子名称: | 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, RPS6KB1 protein | | 著者 | Wang, J, Zhong, C, Ding, J. | | 登録日 | 2013-06-07 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of S6K1 provide insights into the regulation mechanism of S6K1 by the hydrophobic motif
Biochem.J., 454, 2013
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4LAN
 | | Crystal structure of Cordyceps militaris IDCase H195A mutant | | 分子名称: | Uracil-5-carboxylate decarboxylase, ZINC ION | | 著者 | Xu, S, Li, W, Zhu, J, Ding, J. | | 登録日 | 2013-06-20 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4L3L
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4LAO
 | | Crystal structure of Cordyceps militaris IDCase H195A mutant (Zn) | | 分子名称: | Cordyceps militaris IDCase, DI(HYDROXYETHYL)ETHER, ZINC ION | | 著者 | Xu, S, Li, W, Zhu, J, Ding, J. | | 登録日 | 2013-06-20 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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4LAK
 | | Crystal structure of Cordyceps militaris IDCase D323N mutant in apo form | | 分子名称: | Uracil-5-carboxylate decarboxylase, ZINC ION | | 著者 | Xu, S, Li, W, Zhu, J, Wang, R, Li, Z, Xu, G.L, Ding, J. | | 登録日 | 2013-06-20 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
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3PPV
 | | Crystal structure of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | CALCIUM ION, SULFATE ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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3PPX
 | | Crystal structure of the N1602A mutant of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | SODIUM ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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3PPW
 | | Crystal structure of the D1596A mutant of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | SODIUM ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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3PPY
 | | Crystal structure of the D1596A/N1602A double mutant of an engineered VWF A2 domain (N1493C and C1670S) | | 分子名称: | SODIUM ION, von Willebrand factor | | 著者 | Zhou, M, Dong, X, Zhong, C, Ding, J. | | 登録日 | 2010-11-25 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13
Blood, 117, 2011
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