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5VI5
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BU of 5vi5 by Molmil
Structure of Mycobacterium smegmatis transcription initiation complex with a full transcription bubble
分子名称: 1,2-ETHANEDIOL, DNA (44-MER), DNA (49-MER), ...
著者Darst, S.A, Campbell, E.A, Lilic, M.
登録日2017-04-14
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.196 Å)
主引用文献Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Nat Commun, 8, 2017
6M7J
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BU of 6m7j by Molmil
Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin
分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2018-08-20
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
2Z2S
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BU of 2z2s by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
分子名称: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
著者Darst, S.A, Campbell, E.A.
登録日2007-05-26
公開日2008-02-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
1GRJ
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BU of 1grj by Molmil
GREA TRANSCRIPT CLEAVAGE FACTOR FROM ESCHERICHIA COLI
分子名称: GREA PROTEIN
著者Darst, S.A, Stebbins, C.E.
登録日1995-05-02
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the GreA transcript cleavage factor from Escherichia coli.
Nature, 373, 1995
3BMB
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BU of 3bmb by Molmil
Crystal structure of a new RNA polymerase interacting protein
分子名称: CHLORIDE ION, Regulator of nucleoside diphosphate kinase, SULFATE ION
著者Darst, S.A, Lamour, V.
登録日2007-12-12
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of Escherichia coli Rnk, a new RNA polymerase-interacting protein.
J.Mol.Biol., 383, 2008
4G8X
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BU of 4g8x by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
分子名称: ORF067, RNA polymerase sigma factor rpoD
著者Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A.
登録日2012-07-23
公開日2013-08-07
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
4G6D
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BU of 4g6d by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
分子名称: ORF067, RNA polymerase sigma factor rpoD
著者Darst, S.A, Osmundson, J.S.
登録日2012-07-18
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9971 Å)
主引用文献Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
4G94
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BU of 4g94 by Molmil
G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex
分子名称: ORF067, RNA polymerase sigma factor rpoD
著者Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A.
登録日2012-07-23
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9971 Å)
主引用文献Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein.
Cell(Cambridge,Mass.), 151, 2012
3LTI
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BU of 3lti by Molmil
Crystal structure of the Escherichia coli RNA polymerase beta subunit beta2-betai4 domains
分子名称: DNA-directed RNA polymerase subunit beta
著者Darst, S.A, Opalka, N.
登録日2010-02-16
公開日2010-10-20
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
Plos Biol., 8, 2010
3LU0
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BU of 3lu0 by Molmil
Molecular model of Escherichia coli core RNA polymerase
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Darst, S.A.
登録日2010-02-16
公開日2010-09-29
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (11.2 Å)
主引用文献Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
Plos Biol., 8, 2010
3MLQ
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BU of 3mlq by Molmil
Crystal structure of the Thermus thermophilus transcription-repair coupling factor RNA polymerase interacting domain with the Thermus aquaticus RNA polymerase beta1 domain
分子名称: DNA-directed RNA polymerase subunit beta, PHOSPHATE ION, Transcription-repair coupling factor
著者Darst, S.A, Westblade, L.F, Campbell, E.A.
登録日2010-04-18
公開日2010-10-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction.
Nucleic Acids Res., 38, 2010
6EEC
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BU of 6eec by Molmil
Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin
分子名称: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2018-08-13
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6EDT
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BU of 6edt by Molmil
Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter
分子名称: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2018-08-10
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY
主引用文献Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
6EE8
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BU of 6ee8 by Molmil
Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter
分子名称: DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2018-08-13
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
Nature, 565, 2019
5UI5
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BU of 5ui5 by Molmil
Crystal structure of Aquifex aeolicus sigmaN bound to promoter DNA
分子名称: DNA (30-MER), DNA (31-MER), RNA polymerase sigma factor RpoN
著者Darst, S.A, Campbell, E.A, Rajashankar, K.
登録日2017-01-12
公開日2017-02-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TJG
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BU of 5tjg by Molmil
Thermus aquaticus delta1.1-sigmaA holoenzyme/downstream-fork promoter complex with an open clamp
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*A)-3'), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Bae, B.
登録日2016-10-04
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献RNA polymerase motions during promoter melting.
Science, 356, 2017
5UI8
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BU of 5ui8 by Molmil
structure of sigmaN-holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Darst, S.A, Campbell, E.A.
登録日2017-01-13
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.76 Å)
主引用文献Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6C05
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BU of 6c05 by Molmil
Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
登録日2017-12-27
公開日2018-03-28
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (5.15 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6C04
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BU of 6c04 by Molmil
Mtb RNAP Holo/RbpA/double fork DNA -closed clamp
分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
登録日2017-12-27
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6C06
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BU of 6c06 by Molmil
Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
登録日2017-12-27
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.15 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6BZO
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BU of 6bzo by Molmil
Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA
分子名称: DNA (26-MER), DNA (32-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2017-12-25
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
1L9Z
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BU of 1l9z by Molmil
Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution
分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
著者Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A.
登録日2002-03-27
公開日2002-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.
Science, 296, 2002
5VT0
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BU of 5vt0 by Molmil
Escherichia coli 6S RNA derivative in complex with Escherichia coli RNA polymerase sigma70-holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Chen, J, Darst, S.A.
登録日2017-05-15
公開日2017-11-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase.
Mol. Cell, 68, 2017
2EYQ
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BU of 2eyq by Molmil
Crystal structure of Escherichia coli transcription-repair coupling factor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Transcription-repair coupling factor
著者Deaconescu, A.M, Darst, S.A.
登録日2005-11-09
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for bacterial transcription-coupled DNA repair.
Cell(Cambridge,Mass.), 124, 2006
2ETN
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BU of 2etn by Molmil
Crystal structure of Thermus aquaticus Gfh1
分子名称: anti-cleavage anti-GreA transcription factor Gfh1
著者Lamour, V, Hogan, B.P, Erie, D.A, Darst, S.A.
登録日2005-10-27
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage.
J.Mol.Biol., 356, 2006

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