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1DVF
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BU of 1dvf by Molmil
IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX
分子名称: FV D1.3, FV E5.2, ZINC ION
著者Braden, B.C, Fields, B.A, Ysern, X, Dall'Acqua, W, Goldbaum, F.A, Poljak, R.J, Mariuzza, R.A.
登録日1996-04-13
公開日1996-08-17
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution.
J.Mol.Biol., 264, 1996
1A2Y
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BU of 1a2y by Molmil
HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ...
著者Tsuchiya, D, Mariuzza, R.A.
登録日1998-01-13
公開日1998-04-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
1KIP
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BU of 1kip by Molmil
FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
分子名称: LYSOZYME, MONOCLONAL ANTIBODY D1.3
著者Fields, B.A, Poljak, R.J, Mariuzza, R.A.
登録日1996-10-23
公開日1996-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIR
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BU of 1kir by Molmil
FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
分子名称: LYSOZYME, MONOCLONAL ANTIBODY D1.3
著者Fields, B.A, Poljak, R.J, Mariuzza, R.A.
登録日1996-10-23
公開日1996-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIQ
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BU of 1kiq by Molmil
FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
分子名称: LYSOZYME, MONOCLONAL ANTIBODY D1.3
著者Fields, B.A, Poljak, R.J, Mariuzza, R.A.
登録日1996-10-23
公開日1996-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
6ATT
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BU of 6att by Molmil
39S Fab bound to HER2 ecd
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 39S Fab heavy chain, ...
著者Oganesyan, V.Y, Dall'Acqua, W.F.
登録日2017-08-29
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
J. Biol. Chem., 293, 2018
4UB0
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BU of 4ub0 by Molmil
New design for monovalent bispecific IgG through cysteine engineering of the CH1-CL interface
分子名称: IgG1, heavy chain, light chain
著者Oganesyan, V.Y, Dall'Acqua, W.F.
登録日2014-08-11
公開日2015-07-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Improving target cell specificity using a novel monovalent bispecific IgG design.
Mabs, 7, 2015
6WIB
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BU of 6wib by Molmil
Next generation monomeric IgG4 Fc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 4, ZINC ION
著者Oganesyan, V.Y, Shan, L, Dall'Acqua, W, van Dyk, N.
登録日2020-04-09
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
1VFB
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BU of 1vfb by Molmil
BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
分子名称: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Bhat, T.N, Poljak, R.J.
登録日1993-12-03
公開日1994-05-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Proc.Natl.Acad.Sci.USA, 91, 1994
1VFA
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BU of 1vfa by Molmil
BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Bhat, T.N, Poljak, R.J.
登録日1993-12-03
公開日1994-05-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Proc.Natl.Acad.Sci.USA, 91, 1994
1A7N
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BU of 1a7n by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Marks, C, Henrick, K, Winter, G.
登録日1998-03-16
公開日1998-04-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7P
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BU of 1a7p by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) ENGINEERED MUTANT PRO95L->SER ON VARIANT CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
分子名称: ACETIC ACID, IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Marks, C, Henrick, K, Winter, G.
登録日1998-03-16
公開日1998-04-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7Q
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BU of 1a7q by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Marks, C, Henrick, K, Winter, G.
登録日1998-03-16
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7O
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BU of 1a7o by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R96L DELETION MUTANT ON VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Marks, C, Henrick, K, Winter, G.
登録日1998-03-16
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7R
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BU of 1a7r by Molmil
FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT CHAIN L GLU81->ASP
分子名称: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN)
著者Marks, C, Henrick, K, Winter, G.
登録日1998-03-16
公開日1998-04-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献X-Ray Structures of D1.3 Fv Mutants
To be Published

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