3GS1
| An all-RNA Hairpin Ribozyme with mutation A38N1dA | Descriptor: | 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), ... | Authors: | Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. | Deposit date: | 2009-03-26 | Release date: | 2009-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
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3GS5
| An all-RNA hairpin ribozyme A38N1dA variant with a product mimic substrate strand | Descriptor: | 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (25-MER), ... | Authors: | Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. | Deposit date: | 2009-03-26 | Release date: | 2009-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
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3GS8
| An all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strand | Descriptor: | 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, COBALT HEXAMMINE(III), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), ... | Authors: | Spitale, R.C, Volpini, R, Heller, M.G, Krucinska, J, Cristalli, G, Wedekind, J.E. | Deposit date: | 2009-03-26 | Release date: | 2009-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Identification of an imino group indispensable for cleavage by a small ribozyme. J.Am.Chem.Soc., 131, 2009
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3I2R
| Crystal structure of the hairpin ribozyme with a 2',5'-linked substrate with N1-deazaadenosine at position A9 | Descriptor: | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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3I2S
| Crystal structure of the hairpin ribozyme with a 2'OMe substrate and N1-deazaadenosine at position A10 | Descriptor: | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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3I2Q
| Crystal structure of the hairpin ribozyme with 2'OMe substrate strand and N1-deazaadenosine at position A9 | Descriptor: | 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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3I2U
| Crystal structure of the haiprin ribozyme with a 2',5'-linked substrate and N1-deazaadenosine at position A10 | Descriptor: | 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3', 5'-R(*UP*CP*GP*UP*GP*GP*UP*AP*CP*AP*UP*UP*AP*CP*CP*UP*GP*CP*C)-3', COBALT HEXAMMINE(III), ... | Authors: | Wedekind, J.E, Spitale, R.C, Krucinska, J. | Deposit date: | 2009-06-29 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Single-atom imino substitutions at A9 and A10 reveal distinct effects on the fold and function of the hairpin ribozyme catalytic core. Biochemistry, 48, 2009
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