1BK6
 
 | | KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS | | 分子名称: | KARYOPHERIN ALPHA, LARGE T ANTIGEN | | 著者 | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | 登録日 | 1998-07-14 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
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1BK5
 | | KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | COBALT (II) ION, KARYOPHERIN ALPHA | | 著者 | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | | 登録日 | 1998-07-14 | | 公開日 | 1999-01-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
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1BCU
 | | ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN | | 分子名称: | ALPHA-THROMBIN, HIRUGEN, PROFLAVIN | | 著者 | Conti, E, Rivetti, C, Wonacott, A, Brick, P. | | 登録日 | 1998-05-02 | | 公開日 | 1998-10-14 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
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1AMU
 | | PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE | | 分子名称: | ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ... | | 著者 | Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P. | | 登録日 | 1997-06-18 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
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1EE4
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1EE5
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2FAL
 | | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | | 分子名称: | CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | | 登録日 | 1993-06-14 | | 公開日 | 1993-10-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
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2FAM
 | | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | | 著者 | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | | 登録日 | 1993-07-20 | | 公開日 | 1993-10-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
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1LCI
 | | FIREFLY LUCIFERASE | | 分子名称: | LUCIFERASE | | 著者 | Conti, E, Franks, N.P, Brick, P. | | 登録日 | 1996-06-01 | | 公開日 | 1997-03-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
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8R8R
 | | Cryo-EM structure of the human mPSF with PAPOA C-terminus peptide (PAPOAc) | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*A)-3'), ... | | 著者 | Todesca, S, Sandmeir, F, Keidel, A, Conti, E. | | 登録日 | 2023-11-29 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Molecular basis of human polyA polymerase recruitment by mPSF.
Rna, 2024
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1BA3
 | | FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM | | 分子名称: | LUCIFERASE, TRIBROMOMETHANE | | 著者 | Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P. | | 登録日 | 1998-04-21 | | 公開日 | 1998-11-11 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
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5JEA
 | | Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ... | | 著者 | Kowalinski, E, Ebert, J, Stegmann, E, Conti, E. | | 登録日 | 2016-04-18 | | 公開日 | 2016-07-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex.
Mol.Cell, 63, 2016
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8QCB
 | | CryoEM structure of a S. Cerevisiae Ski2387 complex in the open state | | 分子名称: | Antiviral helicase SKI2, Antiviral protein SKI8, Superkiller protein 3, ... | | 著者 | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | 登録日 | 2023-08-25 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
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8QCA
 | | CryoEM structure of a S. Cerevisiae Ski2387 complex in the closed state bound to RNA | | 分子名称: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | | 著者 | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | 登録日 | 2023-08-25 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
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8Q9T
 | | CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA | | 分子名称: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | | 著者 | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | 登録日 | 2023-08-21 | | 公開日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
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8QCF
 | | yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ... | | 著者 | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | | 登録日 | 2023-08-25 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
Mol.Cell, 83, 2023
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6YVH
 | | CWC22-CWC27-EIF4A3 Complex | | 分子名称: | Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog | | 著者 | Basquin, J, Busetto, V, LeHir, H, Conti, E. | | 登録日 | 2020-04-28 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Nucleic Acids Res., 48, 2020
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1A0E
 | | XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA | | 分子名称: | COBALT (II) ION, XYLOSE ISOMERASE | | 著者 | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | 登録日 | 1997-11-28 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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4N0L
 | | Methanopyrus kandleri Csm3 crystal structure | | 分子名称: | Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain, ZINC ION | | 著者 | Hrle, A, Su, A.A, Ebert, J, Benda, C, Conti, E, Randau, L. | | 登録日 | 2013-10-02 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3.
Rna Biol., 10, 2013
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1W3B
 | | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | | 分子名称: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | | 著者 | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | | 登録日 | 2004-07-14 | | 公開日 | 2004-09-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
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1YA0
 | | Crystal structure of the N-terminal domain of human SMG7 | | 分子名称: | SMG-7 transcript variant 2, SULFATE ION | | 著者 | Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E. | | 登録日 | 2004-12-17 | | 公開日 | 2005-03-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
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3N89
 | | KH domains | | 分子名称: | Defective in germ line development protein 3, isoform a | | 著者 | Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E. | | 登録日 | 2010-05-28 | | 公開日 | 2010-09-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.789 Å) | | 主引用文献 | Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
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7AQO
 | | yeast THO-Sub2 complex dimer | | 分子名称: | BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... | | 著者 | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | | 登録日 | 2020-10-22 | | 公開日 | 2020-12-02 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
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7APX
 | | yeast THO-Sub2 complex | | 分子名称: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... | | 著者 | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | | 登録日 | 2020-10-20 | | 公開日 | 2020-12-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex.
Elife, 9, 2020
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5JNB
 | | structure of GLD-2/RNP-8 complex | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Poly(A) RNA polymerase gld-2, ... | | 著者 | Nakel, K, Bonneau, F, Basquin, C, Eckmann, C.R, Conti, E. | | 登録日 | 2016-04-29 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.486 Å) | | 主引用文献 | Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity.
Rna, 22, 2016
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