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2W79
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BU of 2w79 by Molmil
Establishing wild-type levels of catalytic activity on natural and artificial (ba)8-barrel protein scaffolds
Descriptor: 1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, CHLORIDE ION
Authors:Claren, J, Malisi, C, Hocker, B, Sterner, R.
Deposit date:2008-12-21
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Establishing Wild-Type Levels of Catalytic Activity on Natural and Artificial (Beta Alpha)8- Barrel Protein Scaffolds.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W6R
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BU of 2w6r by Molmil
Crystal structure of an artificial (ba)8-barrel protein designed from identical half barrels
Descriptor: IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF
Authors:Hocker, B, Lochner, A, Seitz, T, Claren, J, Sterner, R.
Deposit date:2008-12-18
Release date:2009-02-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-Resolution Crystal Structure of an Artificial (Betaalpha)(8)-Barrel Protein Designed from Identical Half-Barrels.
Biochemistry, 48, 2009
4EWN
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BU of 4ewn by Molmil
Structure of HisF-D130V+D176V with bound rCdRP
Descriptor: 1-(O-carboxy-phenylamino)-1-deoxy-D-ribulose-5-phosphate, Imidazole glycerol phosphate synthase subunit HisF
Authors:Reisinger, B, Bocola, M, Rajendran, C, List, F, Sterner, R.
Deposit date:2012-04-27
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:A sugar isomerization reaction established on various (beta-alpha)8-barrel scaffolds is based on substrate-assisted catalysis
Protein Eng.Des.Sel., 25, 2012
6VTY
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BU of 6vty by Molmil
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM483
Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Deng, X, Phillips, M.
Deposit date:2020-02-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
J.Med.Chem., 63, 2020
6VTN
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BU of 6vtn by Molmil
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM557
Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Deng, X, Phillips, M.
Deposit date:2020-02-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
J.Med.Chem., 63, 2020

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