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7UEK
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BU of 7uek by Molmil
Crystal structure of a de novo designed ovoid TIM barrel OT3
Descriptor: OT3
Authors:Chu, A.E, Fernandez, D, Huang, P.-S.
Deposit date:2022-03-21
Release date:2023-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design.
Biodes Res, 2022, 2022
7RAA
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BU of 7raa by Molmil
Designed StabIL-2 seq15
Descriptor: Interleukin-2, MAGNESIUM ION
Authors:Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C.
Deposit date:2021-06-30
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RA9
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BU of 7ra9 by Molmil
Designed StabIL-2 seq1
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Interleukin-2, PHOSPHATE ION
Authors:Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C.
Deposit date:2021-06-30
Release date:2022-03-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
7KCH
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BU of 7kch by Molmil
Myosin XI-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gong, R, Alushin, G.M.
Deposit date:2020-10-05
Release date:2021-01-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.33 Å)
Cite:Optical control of fast and processive engineered myosins in vitro and in living cells.
Nat.Chem.Biol., 17, 2021
8TCE
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BU of 8tce by Molmil
Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3353871
Descriptor: (2S)-3-phenyl-2-[(3R)-pyrrolidin-3-yl]propanoic acid, Apolipoprotein(a)
Authors:Hendle, J, Weichert, K, Sauder, J.M.
Deposit date:2023-06-30
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
8V9B
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BU of 8v9b by Molmil
Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732
Descriptor: (2S,2'S)-3,3'-[carbonylbis(azanediyl-3,1-phenylene)]bis{2-[(3R)-pyrrolidin-1-ium-3-yl]propanoate}, Apolipoprotein(a), MAGNESIUM ION, ...
Authors:Hendle, J, Weichert, K, Sauder, J.M.
Deposit date:2023-12-07
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
8V8Z
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BU of 8v8z by Molmil
Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3473329
Descriptor: Apolipoprotein(a), muvalaplin
Authors:Hendle, J, Weichert, K, Sauder, J.M.
Deposit date:2023-12-06
Release date:2024-05-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024

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