6HJO
 
 | | Myxococcus xanthus MglA bound to GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA | | 著者 | Varela, P.F, Cherfils, J. | | 登録日 | 2018-09-04 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
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6HJH
 | | Myxococcus xanthus MglA bound to GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA | | 著者 | Varela, P.F, Cherfils, J. | | 登録日 | 2018-09-03 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
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1OIX
 | | X-ray structure of the small G protein Rab11a in complex with GDP and Pi | | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | | 登録日 | 2003-06-26 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystallographic Evidence for Substrate-Assisted GTP Hydrolysis by a Small GTP Binding Protein
Structure, 13, 2005
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4BEP
 | | Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein (apo-form) | | 分子名称: | MAGNESIUM ION, PHOSPHOCHOLINE TRANSFERASE ANKX, SULFATE ION | | 著者 | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | | 登録日 | 2013-03-12 | | 公開日 | 2013-04-24 | | 最終更新日 | 2013-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain.
Embo J., 32, 2013
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4BES
 | | Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate and phosphocholine | | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, PHOSPHOCHOLINE, PHOSPHOCHOLINE TRANSFERASE ANKX, ... | | 著者 | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | | 登録日 | 2013-03-12 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain.
Embo J., 32, 2013
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4BET
 | | Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein (inactive H229A mutant) in complex with cytidine-diphosphate-choline | | 分子名称: | GLYCEROL, PHOSPHOCHOLINE TRANSFERASE ANKX, SULFATE ION, ... | | 著者 | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | | 登録日 | 2013-03-12 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain.
Embo J., 32, 2013
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4BER
 | | Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate | | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | | 登録日 | 2013-03-12 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain.
Embo J., 32, 2013
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1OIV
 | | X-ray structure of the small G protein Rab11a in complex with GDP | | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, RAS-RELATED PROTEIN RAB-11A, ... | | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | | 登録日 | 2003-06-26 | | 公開日 | 2004-01-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes
J.Biol.Chem., 279, 2004
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5NLV
 | | Brag2 Sec7-PH (390-763) | | 分子名称: | IQ motif and SEC7 domain-containing protein 1 | | 著者 | Nawrotek, A, Cherfils, J. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NLY
 | | Brag2 Sec7-PH (390-763), P212121 | | 分子名称: | IQ motif and SEC7 domain-containing protein 1, PHOSPHATE ION | | 著者 | Nawrotek, A, Cherfils, J. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4C7P
 | | Crystal structure of Legionella pneumophila RalF F255K mutant | | 分子名称: | GLYCEROL, RALF | | 著者 | Folly-Klan, M, Alix, E, Stalder, D, Ray, P, Duarte, L.V, Delprato, A, Zeghouf, M, Antonny, B, Campanacci, V, Roy, C.R, Cherfils, J. | | 登録日 | 2013-09-24 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Novel Membrane Sensor Controls the Localization and Arfgef Activity of Bacterial Ralf.
Plos Pathog., 9, 2013
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4D7R
 | | Crystal structure of a chimeric protein with the Sec7 domain of Rickettsia prowazekii RalF and the capping domain of Legionella pneumophila RalF | | 分子名称: | PROLINE/BETAINE TRANSPORTER, RALF | | 著者 | Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V. | | 登録日 | 2014-11-27 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf.
J.Struct.Biol., 189, 2015
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4D7Q
 | | Crystal structure of a chimeric protein with the Sec7 domain of Legionella pneumophila RalF and the capping domain of Rickettsia prowazekii RalF | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V. | | 登録日 | 2014-11-27 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf.
J.Struct.Biol., 189, 2015
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1OIW
 | | X-ray structure of the small G protein Rab11a in complex with GTPgammaS | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, RAS-RELATED PROTEIN RAB-11A | | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | | 登録日 | 2003-06-26 | | 公開日 | 2004-01-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes
J.Biol.Chem., 279, 2004
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6EP0
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6ERB
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6EP5
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6EP2
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6ER8
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6FNE
 | | Structure of human Brag2 (Sec7-PH domains) with the inhibitor Bragsin bound to the PH domain | | 分子名称: | (2~{S})-6-methyl-5-nitro-2-(trifluoromethyl)-2,3-dihydrochromen-4-one, IQ motif and SEC7 domain-containing protein 1, NONAETHYLENE GLYCOL | | 著者 | Nawrotek, A, Zeghouf, M, Cherfils, J. | | 登録日 | 2018-02-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.
Nat.Chem.Biol., 15, 2019
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4A4P
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1KU1
 | | Crystal Structure of the Sec7 Domain of Yeast GEA2 | | 分子名称: | ARF guanine-nucleotide exchange factor 2 | | 著者 | Renault, L, Christova, P, Guibert, B, Pasqualato, S, Cherfils, J. | | 登録日 | 2002-01-20 | | 公開日 | 2002-03-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
Biochemistry, 41, 2002
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6H7E
 | | GEF regulatory domain | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ... | | 著者 | Ferrandez, Y, Cherfils, J, Peurois, F. | | 登録日 | 2018-07-31 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Membranes prime the RapGEF EPAC1 to transduce cAMP signaling.
Nat Commun, 14, 2023
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1ZNY
 | | Crystal Structure Of Mycobacterium tuberculosis Guanylate Kinase In Complex With GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase | | 著者 | Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J. | | 登録日 | 2005-05-12 | | 公開日 | 2005-11-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Proteins, 62, 2006
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1ZNZ
 | | Crystal Structure Of The Reduced Form Of Mycobacterium tuberculosis Guanylate Kinase In Complex With GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase | | 著者 | Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J. | | 登録日 | 2005-05-12 | | 公開日 | 2005-11-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase
Proteins, 62, 2006
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