7WTE
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | Descriptor: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTB
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTA
| Cryo-EM structure of human pyruvate carboxylase in apo state | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTD
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTC
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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8FCY
| Engineered human dynein motor domain in microtubule-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-01 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FDT
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-04 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FD6
| Engineered human dynein motor domain in the microtubule-unbound state in the buffer containing ATP-Vi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, ... | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-02 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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8FDU
| Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex in the buffer containing ATP-Vi (local refined on AAA3-AAA5 and LIS1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1,Serine--tRNA ligase, Platelet-activating factor acetylhydrolase IB subunit beta,Platelet-activating factor acetylhydrolase IB subunit beta,human LIS1 protein with a SNAP tag | Authors: | Ton, W, Wang, Y, Chai, P. | Deposit date: | 2022-12-04 | Release date: | 2023-06-21 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat.Struct.Mol.Biol., 30, 2023
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7UIM
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7UIN
| CryoEM Structure of an Group II Intron Retroelement | Descriptor: | AMMONIUM ION, DNA (37-MER), E.r IIC Intron, ... | Authors: | Chung, K, Xu, L. | Deposit date: | 2022-03-29 | Release date: | 2022-11-23 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of a mobile intron retroelement poised to attack its structured DNA target Science, 378, 2022
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7KEK
| Structure of the free outer-arm dynein in pre-parallel state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ... | Authors: | Rao, Q, Zhang, K. | Deposit date: | 2020-10-11 | Release date: | 2021-09-29 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
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7K5B
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7K58
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7N32
| protofilaments of microtubule doublets bound to outer-arm dynein | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Rao, Q, Zhang, K. | Deposit date: | 2021-05-31 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
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7MWG
| 16-nm repeat microtubule doublet | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Rao, Q, Zhang, K. | Deposit date: | 2021-05-17 | Release date: | 2021-09-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
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7N61
| structure of C2 projections and MIPs | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FAP147, FAP178, ... | Authors: | Han, L, Zhang, K. | Deposit date: | 2021-06-07 | Release date: | 2022-05-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of an active central apparatus. Nat.Struct.Mol.Biol., 29, 2022
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7N6G
| C1 of central pair | Descriptor: | CPC1, Calmodulin, DPY30, ... | Authors: | Han, L, Zhang, K. | Deposit date: | 2021-06-08 | Release date: | 2022-05-18 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of an active central apparatus. Nat.Struct.Mol.Biol., 29, 2022
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