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6HPC
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BU of 6hpc by Molmil
Crystal structure of the HicB antitoxin from E. coli
Descriptor: Antitoxin HicB
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
6HPB
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BU of 6hpb by Molmil
Crystal structure of the E.coli HicAB toxin-antitoxin complex
Descriptor: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
5IQQ
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BU of 5iqq by Molmil
Crystal structure of the human RBM7 RRM domain
Descriptor: RNA-binding protein 7
Authors:Sofos, N, Winkler, M.B.L, Brodersen, D.E.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:RRM domain of human RBM7: purification, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 72, 2016
4R71
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BU of 4r71 by Molmil
Structure of the Qbeta holoenzyme complex in the P1211 crystal form
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ...
Authors:Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R.
Deposit date:2014-08-26
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
6ZI1
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BU of 6zi1 by Molmil
Crystal structure of the isolated H. influenzae VapD toxin (D7N mutant)
Descriptor: Endoribonuclease VapD
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-06-24
Release date:2020-10-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021
6ZI0
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BU of 6zi0 by Molmil
Crystal structure of the isolated H. influenzae VapD toxin (wildtype)
Descriptor: Endoribonuclease VapD
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-06-24
Release date:2020-10-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021
6ZN8
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BU of 6zn8 by Molmil
Crystal structure of the H. influenzae VapXD toxin-antitoxin complex
Descriptor: Endoribonuclease VapD, VapX
Authors:Bertelsen, M.B, Senissar, M, Nielsen, M.H, Bisiak, F, Cunha, M.V, Molinaro, A.L, Daines, D.A, Brodersen, D.E.
Deposit date:2020-07-06
Release date:2020-11-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Structural Basis for Toxin Inhibition in the VapXD Toxin-Antitoxin System.
Structure, 29, 2021
5K8J
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BU of 5k8j by Molmil
Structure of Caulobacter crescentus VapBC1 (apo form)
Descriptor: GLYCEROL, Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
7AB3
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BU of 7ab3 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S57A)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB5
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BU of 7ab5 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB4
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BU of 7ab4 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S59A)
Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
Authors:Baerentsen, R.L, Brodersen, D.E.
Deposit date:2020-09-06
Release date:2022-01-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
5L6L
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BU of 5l6l by Molmil
Structure of Caulobacter crescentus VapBC1 bound to operator DNA
Descriptor: DNA (27-MER), Ribonuclease VapC, VapB family protein
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
5L6M
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BU of 5l6m by Molmil
Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form)
Descriptor: GLYCEROL, MALONATE ION, Ribonuclease VapC, ...
Authors:Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
Deposit date:2016-05-30
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
6EX0
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BU of 6ex0 by Molmil
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to pppGpp in the post-catalytic state
Descriptor: FE (II) ION, GTP pyrophosphokinase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2017-11-07
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.
J. Biol. Chem., 293, 2018
6EWZ
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BU of 6ewz by Molmil
Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to AMPCPP and GTP in the pre-catalytic state
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, FE (III) ION, GTP pyrophosphokinase, ...
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2017-11-07
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.
J. Biol. Chem., 293, 2018
6EXP
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BU of 6exp by Molmil
Crystal structure of the SIRV3 AcrID1 (gp02) anti-CRISPR protein
Descriptor: SIRV3 AcrID1 (gp02) anti-CRISPR protein
Authors:He, F, Bhoobalan-Chitty, Y, Van, L.B, Kjeldsen, A.L, Dedola, M, Makarova, K.S, Koonin, E.V, Brodersen, D.E, Peng, X.
Deposit date:2017-11-08
Release date:2018-01-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity.
Nat Microbiol, 3, 2018
6THH
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BU of 6thh by Molmil
Crystal structure of type I-D CRISPR-Cas nuclease Cas10d in complex with the SIRV3 AcrID1 (gp02) anti-CRISPR protein
Descriptor: CRISPR-associated protein, CscA, PHOSPHATE ION, ...
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2019-11-20
Release date:2020-10-28
Last modified:2021-06-30
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
Nat Commun, 11, 2020
4V7K
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BU of 4v7k by Molmil
Structure of RelE nuclease bound to the 70S ribosome (postcleavage state)
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
4V4S
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BU of 4v4s by Molmil
Crystal structure of the whole ribosomal complex.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.76 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V4T
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BU of 4v4t by Molmil
Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
Deposit date:2005-10-12
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.46 Å)
Cite:Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
5ED0
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BU of 5ed0 by Molmil
Structure of the Shigella flexneri VapC mutant D7N
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
5ECY
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BU of 5ecy by Molmil
Structure of the Shigella flexneri VapC mutant D98N crystal form 2
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-10-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis on the active site architecture of an activated VapC toxin from Shigella flexneri
to be published
5ECW
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BU of 5ecw by Molmil
Structure of the Shigella flexneri VapC mutant D7A
Descriptor: tRNA(fMet)-specific endonuclease VapC
Authors:Xu, K, Dedic, E, Brodersen, D.E.
Deposit date:2015-10-20
Release date:2016-02-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
1HR0
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BU of 1hr0 by Molmil
CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Morgan-Warren, R.J, Wimberly, B.T, Ramakrishnan, V.
Deposit date:2000-12-20
Release date:2001-01-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
Science, 291, 2001
1IBK
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BU of 1ibk by Molmil
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V.
Deposit date:2001-03-28
Release date:2001-05-04
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001

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數據於2024-05-15公開中

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