3S3L
 
 | | Crystal Structure of CerJ from Streptomyces tendae | | Descriptor: | ACETATE ION, CHLORIDE ION, CerJ | | Authors: | Zocher, G, Hertweck, C, Bretschneider, T, Stehle, T. | | Deposit date: | 2011-05-18 | | Release date: | 2011-12-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis.
Nat.Chem.Biol., 8, 2011
|
|
3T6S
 | | Crystal structure of CerJ from Streptomyces tendae in Complex with CoA | | Descriptor: | COENZYME A, CerJ | | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | | Deposit date: | 2011-07-29 | | Release date: | 2011-12-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis.
Nat.Chem.Biol., 8, 2011
|
|
3T8E
 | | Crystal structure of CerJ from Streptomyces tendae soaked with CerviK | | Descriptor: | ACETATE ION, CerJ | | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | | Deposit date: | 2011-08-01 | | Release date: | 2011-12-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis.
Nat.Chem.Biol., 8, 2011
|
|
3T5Y
 | | Crystal structure of CerJ from Streptomyces tendae - malonic acid covalently linked to the catalytic Cystein C116 | | Descriptor: | ACETATE ION, CerJ | | Authors: | Zocher, G, Bretschneider, T, Hertweck, C, Stehle, T. | | Deposit date: | 2011-07-28 | | Release date: | 2011-12-21 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis.
Nat.Chem.Biol., 8, 2011
|
|
4KC5
 | |
8P01
 | | Crystal structure of human STING ectodomain in complex with BI 7446, a potent cyclic dinucleotide STING agonist with broad-spectrum variant activity for the treatment of cancer | | Descriptor: | 3-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{R})-8-(6-aminopurin-9-yl)-9-fluoranyl-18-oxidanyl-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-6~{H}-imidazo[4,5-d]pyridazin-7-one, Stimulator of interferon genes protein | | Authors: | Nar, H. | | Deposit date: | 2023-05-09 | | Release date: | 2023-07-26 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.094 Å) | | Cite: | Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer.
J.Med.Chem., 66, 2023
|
|
5OHI
 | | Crystal structure of autotaxin in complex with BI-2545 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15-PENTAOXAHEPTADECANE, CALCIUM ION, ... | | Authors: | Hoerer, S. | | Deposit date: | 2017-07-17 | | Release date: | 2018-01-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.
ACS Med Chem Lett, 8, 2017
|
|
5OLB
 | | crystal structure of autotaxin in complex with PF-8380 | | Descriptor: | (3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Hoerer, S, Lammens, A. | | Deposit date: | 2017-07-27 | | Release date: | 2018-01-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.
ACS Med Chem Lett, 8, 2017
|
|
