2PID
 
 | | Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with an adenylate analog | | 分子名称: | 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Tyrosyl-tRNA synthetase | | 著者 | Bonnefond, L, Frugier, M, Touze, E, Lorber, B, Florentz, C, Giege, R, Sauter, C, Rudinger-Thirion, J. | | 登録日 | 2007-04-13 | | 公開日 | 2007-10-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Human Mitochondrial Tyrosyl-tRNA Synthetase Reveals Common and Idiosyncratic Features.
Structure, 15, 2007
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3S7T
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4UP7
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4UPA
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4UP9
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4UP8
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3OQJ
 | | Crystal structure of B. licheniformis CDPS yvmC-BLIC in complex with CAPSO | | 分子名称: | (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Putative uncharacterized protein yvmC | | 著者 | Bonnefond, L, Arai, T, Suzuki, T, Ishitani, R, Nureki, O. | | 登録日 | 2010-09-03 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OQI
 | | Crystal structure of B. licheniformis CDPS yvmC-BLIC in complex with CHES | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Putative uncharacterized protein yvmC | | 著者 | Bonnefond, L, Arai, T, Suzuki, T, Ishitani, R, Nureki, O. | | 登録日 | 2010-09-03 | | 公開日 | 2011-02-23 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3OQH
 | | Crystal structure of B. licheniformis CDPS yvmC-BLIC | | 分子名称: | GLYCEROL, Putative uncharacterized protein yvmC | | 著者 | Bonnefond, L, Arai, T, Suzuki, T, Ishitani, R, Nureki, O. | | 登録日 | 2010-09-03 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3ZXI
 | | Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with a tyrosyl-adenylate analog | | 分子名称: | PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER, TYROSYL-TRNA SYNTHETASE, MITOCHONDRIAL | | 著者 | Bonnefond, L, Frugier, M, Rudinger-Thirion, J, Balg, C, Chenevert, R, Lorber, B, Giege, R, Sauter, C. | | 登録日 | 2011-08-11 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination
Cryst.Growth Des., 11, 2011
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6SQK
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6SQH
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6SQ4
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6SQ3
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6SQI
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4C07
 | | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CaCl2 at 1.5 Angstroms | | 分子名称: | CALCIUM ION, PROTEIN ARGININE N-METHYLTRANSFERASE 6 | | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
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4C03
 | | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 reduced | | 分子名称: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN | | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
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4C08
 | | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CaCl2 at 1.34 Angstroms | | 分子名称: | CALCIUM ION, PENTAETHYLENE GLYCOL, PROTEIN ARGININE N-METHYLTRANSFERASE 6 | | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.338 Å) | | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
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4C06
 | | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with MgCl2 | | 分子名称: | MAGNESIUM ION, PROTEIN ARGININE N-METHYLTRANSFERASE 6 | | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
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4C05
 | | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with SAH | | 分子名称: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.195 Å) | | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
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4C04
 | | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with inhibitor | | 分子名称: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN | | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.576 Å) | | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6.
J.Struct.Biol., 191, 2015
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5FQN
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5FIW
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5FQO
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7NUD
 | | Crystal structure of mouse PRMT6 in complex with inhibitor EML734 | | 分子名称: | Protein arginine N-methyltransferase 6, methyl 6-[3-[[~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]carbamimidoyl]amino]propylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate | | 著者 | Bonnefond, L, Cavarelli, J. | | 登録日 | 2021-03-11 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach.
J.Med.Chem., 65, 2022
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