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STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1991-08-05
公開日	1993-01-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

6LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1991-08-05
公開日	1993-01-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

1P04

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ISOLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P03

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P05

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P06

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.34 Å)
主引用文献	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P02

STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry, 28, 1989

1P09

STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称:	ALPHA-LYTIC PROTEASE, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural plasticity broadens the specificity of an engineered protease. Nature, 339, 1989

1P10

STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Structural plasticity broadens the specificity of an engineered protease. Nature, 339, 1989

1IMB

STRUCTURAL ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES
分子名称:	GADOLINIUM ATOM, INOSITOL MONOPHOSPHATASE, L-MYO-INOSITOL-1-PHOSPHATE
著者	Bone, R.
登録日	1994-02-08
公開日	1995-02-27
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural analysis of inositol monophosphatase complexes with substrates. Biochemistry, 33, 1994

1IMA

STRUCTURAL ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES
分子名称:	D-MYO-INOSITOL-1-PHOSPHATE, GADOLINIUM ATOM, INOSITOL MONOPHOSPHATASE
著者	Bone, R.
登録日	1994-02-08
公開日	1995-02-27
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural analysis of inositol monophosphatase complexes with substrates. Biochemistry, 33, 1994

1P01

Serine protease mechanism. structure of an inhibitory complex oF ALPHA-LYTIC Protease and a tightly bound peptide boronic acid
分子名称:	ALPHA-LYTIC PROTEASE, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1R)-1-(dihydroxyboranyl)-2-methylpropyl]-L-prolinamide, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1989-04-24
公開日	1990-04-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Serine protease mechanism: structure of an inhibitory complex of alpha-lytic protease and a tightly bound peptide boronic acid. Biochemistry, 26, 1987

2LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1991-08-05
公開日	1993-01-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

3LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1991-08-05
公開日	1993-01-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

1IMF

STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:	INOSITOL MONOPHOSPHATASE
著者	Bone, R.
登録日	1994-02-08
公開日	1995-02-27
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis. Biochemistry, 33, 1994

1IMC

STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:	CHLORIDE ION, INOSITOL MONOPHOSPHATASE, MANGANESE (II) ION
著者	Bone, R.
登録日	1994-02-08
公開日	1995-02-27
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis. Biochemistry, 33, 1994

1IME

STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:	CALCIUM ION, INOSITOL MONOPHOSPHATASE
著者	Bone, R.
登録日	1994-02-08
公開日	1995-02-27
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis. Biochemistry, 33, 1994

1IMD

STRUCTURAL STUDIES OF METAL BINDING BY INOSITOL MONOPHOSPHATASE: EVIDENCE FOR TWO-METAL ION CATALYSIS
分子名称:	INOSITOL MONOPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION
著者	Bone, R.
登録日	1994-02-08
公開日	1995-02-27
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis. Biochemistry, 33, 1994

4PHV

X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY
分子名称:	HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE
著者	Bone, R.
登録日	1991-10-04
公開日	1993-10-31
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry J.Am.Chem.Soc., 113, 1991

1P11

CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS
分子名称:	ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR A, PHOSPHONATE ESTER INHIBITOR B(TRANSITION STATE), ...
著者	Bone, R, Agard, D.A.
登録日	1990-10-26
公開日	1993-01-15
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.93 Å)
主引用文献	Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry, 30, 1991

1P12

CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS
分子名称:	ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR, SULFATE ION
著者	Bone, R, Agard, D.A.
登録日	1990-10-26
公開日	1993-01-15
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry, 30, 1991

2HHM

STRUCTURE OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM THERAPY
分子名称:	GADOLINIUM ATOM, INOSITOL MONOPHOSPHATASE, SULFATE ION
著者	Bone, R.
登録日	1992-10-20
公開日	1993-10-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structure of inositol monophosphatase, the putative target of lithium therapy. Proc.Natl.Acad.Sci.USA, 89, 1992

1QBV

CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR
分子名称:	Hirudin, THROMBIN (HEAVY CHAIN), THROMBIN (LIGHT CHAIN), ...
著者	Bone, R, Lu, T, Illig, C.R, Soll, R.M, Spurlino, J.C.
登録日	1999-04-27
公開日	1999-10-27
最終更新日	2017-10-04
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes. J.Med.Chem., 41, 1998

8LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Fujishige, A, Bone, R, Agard, D.A.
登録日	1991-08-05
公開日	1993-01-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

5LPR

STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS
分子名称:	ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者	Fujishige, A, Bone, R, Agard, D.A.
登録日	1991-08-05
公開日	1993-01-15
最終更新日	2012-12-12
実験手法	X-RAY DIFFRACTION (2.13 Å)
主引用文献	Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991

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