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1QK9
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BU of 1qk9 by Molmil
The solution structure of the domain from MeCP2 that binds to methylated DNA
Descriptor: METHYL-CPG-BINDING PROTEIN 2
Authors:Wakefield, R.I.D, Smith, B.O, Nan, X, Free, A, Soteriou, A, Uhrin, D, Bird, A.P, Barlow, P.N.
Deposit date:1999-07-12
Release date:1999-10-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Solution Structure of the Domain from Mecp2 that Binds to Methylated DNA
J.Mol.Biol., 291, 1999
3C2I
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BU of 3c2i by Molmil
The Crystal Structure of Methyl-CpG Binding Domain of Human MeCP2 in Complex with a Methylated DNA Sequence from BDNF
Descriptor: DNA (5'-D(*DAP*DTP*DAP*DGP*DAP*DAP*DGP*DAP*DAP*DTP*DTP*DCP*(5CM)P*DGP*DTP*DTP*DCP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DCP*DTP*DGP*DGP*DAP*DAP*(5CM)P*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DTP*DA)-3'), Methyl-CpG-binding protein 2
Authors:Ho, K.L, McNae, I.W, Schmiedeberg, L, Klose, R.J, Bird, A.P, Walkinshaw, M.D.
Deposit date:2008-01-25
Release date:2008-05-13
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:MeCP2 binding to DNA depends upon hydration at methyl-CpG
Mol.Cell, 29, 2008
5NAF
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BU of 5naf by Molmil
Co-crystal structure of an MeCP2 peptide with TBLR1 WD40 domain
Descriptor: F-box-like/WD repeat-containing protein TBL1XR1, GLYCEROL, Methyl-CpG-binding protein 2
Authors:Kruusvee, V, Cook, A.G.
Deposit date:2017-02-27
Release date:2017-03-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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