8VAL
 
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8VAM
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8VAR
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8VAP
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3TVI
 | | Crystal structure of Clostridium acetobutylicum aspartate kinase (CaAK): An important allosteric enzyme for industrial amino acids production | | Descriptor: | ASPARTIC ACID, Aspartokinase, LYSINE | | Authors: | Manjasetty, B.A, Chance, M.R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2011-09-20 | | Release date: | 2011-11-09 | | Last modified: | 2021-02-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of Clostridium acetobutylicum Aspartate kinase (CaAK): An important allosteric enzyme for amino acids production.
Biotechnol Rep (Amst), 3, 2014
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3U60
 | | Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | | Deposit date: | 2011-10-11 | | Release date: | 2012-01-04 | | Method: | X-RAY DIFFRACTION (3.34 Å) | | Cite: | How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
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3U48
 | | From soil to structure: a novel dimeric family 3-beta-glucosidase isolated from compost using metagenomic analysis | | Descriptor: | CALCIUM ION, JMB19063, beta-D-glucopyranose | | Authors: | McAndrew, R.P, Park, J.I, Reindl, W, Friedland, G.D, D'haeseleer, P, Northen, T, Sale, K.L, Simmons, B.A, Adams, P.D. | | Deposit date: | 2011-10-07 | | Release date: | 2013-04-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | From soil to structure: a novel dimeric family 3-beta-glucosidase isolated from compost using metagenomic analysis
To be Published
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3U61
 | | Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | | Deposit date: | 2011-10-11 | | Release date: | 2012-01-04 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | How a DNA polymerase clamp loader opens a sliding clamp.
Science, 334, 2011
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3UJT
 | | Structure of the Fab fragment of Ab-52, an antibody that binds the O-antigen of Francisella tularensis | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ab-52 heavy chain, Ab-52 light chain, ... | | Authors: | Rynkiewicz, M.J, Lu, Z, Hui, J.H, Sharon, J, Seaton, B.A. | | Deposit date: | 2011-11-08 | | Release date: | 2012-07-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Analysis of a Protective Epitope of the Francisella tularensis O-Polysaccharide.
Biochemistry, 51, 2012
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3URE
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3URC
 | | T181G mutant of alpha-Lytic Protease | | Descriptor: | Alpha-lytic protease, GLYCEROL, SULFATE ION | | Authors: | Kelch, B.A, Agard, D.A. | | Deposit date: | 2011-11-22 | | Release date: | 2012-05-23 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3URD
 | | T181A mutant of alpha-Lytic Protease | | Descriptor: | Alpha-lytic protease, GLYCEROL, SULFATE ION | | Authors: | Kelch, B.A, Agard, D.A. | | Deposit date: | 2011-11-22 | | Release date: | 2012-05-23 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.08 Å) | | Cite: | Functional modulation of a protein folding landscape via side-chain distortion.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4AON
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4AE7
 | | Crystal structure of human THEM5 | | Descriptor: | THIOESTERASE SUPERFAMILY MEMBER 5 | | Authors: | Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A. | | Deposit date: | 2012-01-09 | | Release date: | 2012-07-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
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4AE8
 | | Crystal structure of human THEM4 | | Descriptor: | THIOESTERASE SUPERFAMILY MEMBER 4 | | Authors: | Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A. | | Deposit date: | 2012-01-09 | | Release date: | 2012-07-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.594 Å) | | Cite: | Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
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4ACP
 | | Deactivation of human IgG1 Fc by endoglycosidase treatment | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG GAMMA-1 CHAIN C REGION | | Authors: | Raman, K, Bowden, T.A, Krishna, B.A, Dwek, R.A, Crispin, M, Scanlan, C.N. | | Deposit date: | 2011-12-16 | | Release date: | 2012-04-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Selective Deactivation of Serum Igg: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions.
J.Mol.Biol., 420, 2012
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4AQC
 | | Triazolopyridine-based Inhibitor of Janus Kinase 2 | | Descriptor: | 8-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine, SULFATE ION, TYROSINE-PROTEIN KINASE JAK2 | | Authors: | Dugan, B.J, Gingrich, D.E, Mesaros, E.F, Milkiewicz, K.L, Curry, M.A, Zulli, A.L, Dobrzanski, P, Serdikoff, C, Jan, M, Angeles, T.S, Albom, M.S, Mason, J.L, Aimone, L.D, Meyer, S.L, Huang, Z, Wells-Knecht, K.J, Ator, M.A, Ruggeri, B.A, Dorsey, B.D. | | Deposit date: | 2012-04-16 | | Release date: | 2012-04-25 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-A]Pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of Cep-33779.
J.Med.Chem., 55, 2012
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4AOK
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4AZD
 | | T57V mutant of aspartate decarboxylase | | Descriptor: | ASPARTATE 1-DECARBOXYLASE, MALONATE ION | | Authors: | Webb, M.E, Yorke, B.A, Kershaw, T, Lovelock, S, Lobley, C.M.C, Kilkenny, M.L, Smith, A.G, Blundell, T.L, Pearson, A.R, Abell, C. | | Deposit date: | 2012-06-25 | | Release date: | 2012-07-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Threonine 57 is Required for the Post-Translational Activation of Escherichia Coli Aspartate Alpha-Decarboxylase
Acta Crystallogr.,Sect.D, 70, 2014
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4C3C
 | | Thaumatin refined against hatrx data for time-point 1 | | Descriptor: | L(+)-TARTARIC ACID, THAUMATIN-1 | | Authors: | Yorke, B.A, Beddard, G.S, Owen, R.L, Pearson, A.R. | | Deposit date: | 2013-08-22 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Time-Resolved Crystallography Using the Hadamard Transform.
Nat.Methods, 11, 2014
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6OP7
 | | Structure of oxidized VIM-20 | | Descriptor: | ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION | | Authors: | Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C. | | Deposit date: | 2019-04-24 | | Release date: | 2019-10-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
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6P5W
 | | Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide | | Descriptor: | 3-methyl-N-[(4S,5S)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide, Lysozyme,DCN1-like protein 1 chimera | | Authors: | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | | Deposit date: | 2019-05-31 | | Release date: | 2019-09-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation.
J.Med.Chem., 62, 2019
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6PEI
 | | Structure of sorbitol dehydrogenase from Sinorhizobium meliloti 1021 | | Descriptor: | Sorbitol dehydrogenase (L-iditol 2-dehydrogenase) | | Authors: | Bailey-Elkin, B.A, Kohlmeier, M.G, Oresnik, I.J, Mark, B.L. | | Deposit date: | 2019-06-20 | | Release date: | 2020-06-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of the sorbitol dehydrogenase SmoS from Sinorhizobium meliloti 1021
Acta Crystallogr.,Sect.D, 77, 2021
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6P5V
 | | Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme,DCN1-like protein 1 fusion, N-[(4S,5S)-1-[(1S)-cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide | | Authors: | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | | Deposit date: | 2019-05-31 | | Release date: | 2019-09-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.398 Å) | | Cite: | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation.
J.Med.Chem., 62, 2019
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6PEJ
 | | Structure of sorbitol dehydrogenase from Sinorhizobium meliloti 1021 bound to sorbitol | | Descriptor: | Sorbitol dehydrogenase (L-iditol 2-dehydrogenase), sorbitol | | Authors: | Bailey-Elkin, B.A, Kohlmeier, M.G, Oresnik, I.J, Mark, B.L. | | Deposit date: | 2019-06-20 | | Release date: | 2020-06-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Characterization of the sorbitol dehydrogenase SmoS from Sinorhizobium meliloti 1021
Acta Crystallogr.,Sect.D, 77, 2021
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