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Crystal structure of human carbonic anhydrase II in complex with a benzenesulfonamide inhibitor
Descriptor:	4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:	Avvaru, B.S, Wagner, J, Robbins, A.H, McKenna, R.
Deposit date:	2010-05-21
Release date:	2011-03-09
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Chem.Commun.(Camb.), 46, 2010

Crystal structure of human carbonic anhydrase II in complex with a benzenesulfonamide inhibitor
Descriptor:	4-{[(pentafluorophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:	Avvaru, B.S, Wagner, J, Robbins, A.H, McKenna, R.
Deposit date:	2010-05-14
Release date:	2011-03-16
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Chem.Commun.(Camb.), 46, 2010

hCarbonic anhydrase II bound to N-(2-fluoro.4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide
Descriptor:	Carbonic anhydrase 2, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:	Biswas, S, McKenna, R.
Deposit date:	2011-03-09
Release date:	2011-05-25
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Bioorg.Med.Chem., 19, 2011