1H6I
 
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6V5D
 | | EROS3 RDC and NOE Derived Ubiquitin Ensemble | | 分子名称: | Ubiquitin | | 著者 | Lange, O.F, Lakomek, N.A, Smith, C.A, Griesinger, C, de Groot, B.L. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-01 | | 最終更新日 | 2020-02-26 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Enhancing NMR derived ensembles with kinetics on multiple timescales.
J.Biomol.Nmr, 74, 2020
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4UN2
 | | Crystal structure of the UBA domain of Dsk2 in complex with Ubiquitin | | 分子名称: | UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2 | | 著者 | Michielssens, S, Peters, J.H, Ban, D, Pratihar, S, Seeliger, D, Sharma, M, Giller, K, Sabo, T.M, Becker, S, Lee, D, Griesinger, C, de Groot, B.L. | | 登録日 | 2014-05-23 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
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2K39
 | | Recognition dynamics up to microseconds revealed from RDC derived ubiquitin ensemble in solution | | 分子名称: | Ubiquitin | | 著者 | Lange, O.F, Lakomek, N.A, Fares, C, Schroder, G, Walter, K, Becker, S, Meiler, J, Grubmuller, H, Griesinger, C, de Groot, B.L. | | 登録日 | 2008-04-25 | | 公開日 | 2008-06-24 | | 最終更新日 | 2019-11-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Science, 320, 2008
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2W1P
 | | 1.4 Angstrom crystal structure of P.pastoris aquaporin, Aqy1, in a closed conformation at pH 8.0 | | 分子名称: | AQUAPORIN PIP2-7 7;, CHLORIDE ION, octyl beta-D-glucopyranoside | | 著者 | Fischer, G, Kosinska-Eriksson, U, Aponte-Santamaria, C, Palmgren, M, Geijer, C, Hedfalk, K, Hohmann, S, de Groot, B.L, Neutze, R, Lindkvist-Petersson, K. | | 登録日 | 2008-10-20 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism
Plos Biol., 7, 2009
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2W2E
 | | 1.15 Angstrom crystal structure of P.pastoris aquaporin, Aqy1, in a closed conformation at pH 3.5 | | 分子名称: | AQUAPORIN PIP2-7 7, CHLORIDE ION, octyl beta-D-glucopyranoside | | 著者 | Fischer, G, Kosinska-Eriksson, U, Aponte-Santamaria, C, Palmgren, M, Geijer, C, Hedfalk, K, Hohmann, S, de Groot, B.L, Neutze, R, Lindkvist-Petersson, K. | | 登録日 | 2008-10-29 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism.1.15 A
Plos Biol., 7, 2009
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8A4L
 | | Lipidic alpha-synuclein fibril - polymorph L2A | | 分子名称: | Alpha-synuclein | | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | | 登録日 | 2022-06-12 | | 公開日 | 2022-08-17 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
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8ADV
 | | Lipidic alpha-synuclein fibril - polymorph L1B | | 分子名称: | Alpha-synuclein | | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | | 登録日 | 2022-07-11 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
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8ADS
 | | Lipidic alpha-synuclein fibril - polymorph L2B | | 分子名称: | Alpha-synuclein | | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | | 登録日 | 2022-07-11 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
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8ADU
 | | Lipidic alpha-synuclein fibril - polymorph L1A | | 分子名称: | Alpha-synuclein | | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | | 登録日 | 2022-07-11 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
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8AEX
 | | Lipidic alpha-synuclein fibril - polymorph L3A | | 分子名称: | Alpha-synuclein | | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | | 登録日 | 2022-07-14 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
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8ADW
 | | Lipidic alpha-synuclein fibril - polymorph L1C | | 分子名称: | Alpha-synuclein | | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | | 登録日 | 2022-07-11 | | 公開日 | 2022-10-12 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
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1LOH
 | | Streptococcus pneumoniae Hyaluronate Lyase in Complex with Hexasaccharide Hyaluronan Substrate | | 分子名称: | Hyaluronate Lyase, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Jedrzejas, M.J, Mello, L.V, De Groot, B.L, Li, S. | | 登録日 | 2002-05-06 | | 公開日 | 2002-08-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
J.Biol.Chem., 277, 2002
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1LXK
 | | Streptococcus pneumoniae Hyaluronate Lyase in Complex with Tetrasaccharide Hyaluronan Substrate | | 分子名称: | Hyaluronate Lyase, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Jedrzejas, M.J, Mello, L.V, De Groot, B.L, Li, S. | | 登録日 | 2002-06-05 | | 公開日 | 2002-08-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
J.Biol.Chem., 277, 2002
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1LXM
 | | Crystal Structure of Streptococcus agalactiae Hyaluronate Lyase Complexed with Hexasaccharide Unit of Hyaluronan | | 分子名称: | HYALURONATE Lyase, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Mello, L.V, de Groot, B.L, Li, S, Jedrzejas, M.J. | | 登録日 | 2002-06-05 | | 公開日 | 2002-10-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and flexibility of Streptococcus agalactiae hyaluronate lyase complex with its substrate. Insights into the mechanism of processive degradation of hyaluronan.
J.Biol.Chem., 277, 2002
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5NFE
 | | Neutron structure of human transthyretin (TTR) T119M mutant at room temperature to 1.85A resolution | | 分子名称: | Transthyretin | | 著者 | Yee, A.W, Moulin, M, Blakeley, M.P, Ostermann, A, Cooper, J.B, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | | 登録日 | 2017-03-14 | | 公開日 | 2019-01-02 | | 最終更新日 | 2019-03-20 | | 実験手法 | NEUTRON DIFFRACTION (1.853 Å), X-RAY DIFFRACTION | | 主引用文献 | A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
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5NFW
 | | Neutron structure of human transthyretin (TTR) S52P mutant at room temperature to 1.8A resolution (quasi-Laue) | | 分子名称: | Transthyretin | | 著者 | Yee, A.W, Moulin, M, Blakeley, M.P, Cooper, J.B, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | | 登録日 | 2017-03-16 | | 公開日 | 2019-01-02 | | 最終更新日 | 2019-03-20 | | 実験手法 | NEUTRON DIFFRACTION (1.8 Å), X-RAY DIFFRACTION | | 主引用文献 | A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
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6VYM
 | | Cryo-EM structure of mechanosensitive channel MscS in PC-18:1 nanodiscs treated with beta-cyclodextran | | 分子名称: | Mechanosensitive channel MscS | | 著者 | Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. | | 登録日 | 2020-02-27 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Visualization of the mechanosensitive ion channel MscS under membrane tension.
Nature, 590, 2021
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6VYL
 | | Cryo-EM structure of mechanosensitive channel MscS in PC-10 nanodiscs | | 分子名称: | Mechanosensitive channel MscS | | 著者 | Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. | | 登録日 | 2020-02-27 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Visualization of the mechanosensitive ion channel MscS under membrane tension.
Nature, 590, 2021
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6VYK
 | | Cryo-EM structure of mechanosensitive channel MscS in PC-18:1 nanodiscs | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mechanosensitive channel MscS | | 著者 | Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. | | 登録日 | 2020-02-27 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Visualization of the mechanosensitive ion channel MscS under membrane tension.
Nature, 590, 2021
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6FFT
 | | Neutron structure of human transthyretin (TTR) S52P mutant in complex with tafamidis at room temperature to 2A resolution (quasi-Laue) | | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | | 著者 | Yee, A.W, Moulin, M, Blakeley, M.P, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | | 登録日 | 2018-01-09 | | 公開日 | 2019-01-02 | | 最終更新日 | 2019-03-20 | | 実験手法 | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | | 主引用文献 | A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun, 10, 2019
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7OOJ
 | | Structure of D-Thr53 Ubiquitin | | 分子名称: | CADMIUM ION, Ubiquitin | | 著者 | Becker, S. | | 登録日 | 2021-05-27 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A litmus test for classifying recognition mechanisms of transiently binding proteins.
Nat Commun, 13, 2022
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2BRV
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2BRW
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6QZJ
 | | Crystal structure of human Aquaporin 7 at 2.2 A resolution | | 分子名称: | Aquaporin-7, GLYCEROL, PHOSPHATE ION | | 著者 | de Mare, S.W.-H, Venskutonyte, R, Eltschkner, S, Lindkvist-Petersson, K. | | 登録日 | 2019-03-11 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7.
Structure, 28, 2020
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