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1APL
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BU of 1apl by Molmil
CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS
分子名称: DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN)
著者Wolberger, C, Vershon, A.K, Liu, B, Johnson, A.D, Pabo, C.O.
登録日1993-10-04
公開日1993-10-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 67, 1991
4WA6
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BU of 4wa6 by Molmil
Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution
分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ...
著者Wolberger, C, Yan, M.
登録日2014-08-28
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution
To Be Published
4W4U
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BU of 4w4u by Molmil
Structure of yeast SAGA DUBm with Sgf73 Y57A mutant at 2.8 angstroms resolution
分子名称: SAGA-associated factor 11, SAGA-associated factor 73, Transcription and mRNA export factor SUS1, ...
著者Wolberger, C, Yan, M.
登録日2014-08-15
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.
J.Mol.Biol., 427, 2015
5H84
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BU of 5h84 by Molmil
Human Gcn5 bound to propionyl-CoA
分子名称: 1,2-ETHANEDIOL, Histone acetyltransferase KAT2A, ISOPROPYL ALCOHOL, ...
著者Wolberger, C, Ringel, A.E.
登録日2015-12-23
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for acyl-group discrimination by human Gcn5L2.
Acta Crystallogr D Struct Biol, 72, 2016
5H86
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BU of 5h86 by Molmil
Human Gcn5 bound to butyryl-CoA
分子名称: 1,2-ETHANEDIOL, Butyryl Coenzyme A, Histone acetyltransferase KAT2A
著者Wolberger, C, Ringel, A.E.
登録日2015-12-23
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural basis for acyl-group discrimination by human Gcn5L2.
Acta Crystallogr D Struct Biol, 72, 2016
3PDH
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BU of 3pdh by Molmil
Structure of Sir2Tm bound to a propionylated peptide
分子名称: Cellular tumor antigen p53 18-residue peptide, NAD-dependent deacetylase, ZINC ION
著者Wolberger, C, Bheda, P.
登録日2010-10-22
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Sir2Tm bound to a propionylated peptide.
Protein Sci., 20, 2011
2GMI
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BU of 2gmi by Molmil
Mms2/Ubc13~Ubiquitin
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 13, Ubiquitin-conjugating enzyme variant MMS2
著者Wolberger, C, Eddins, M.J, Carlile, C.M, Gomez, K.G, Pickart, C.M.
登録日2006-04-06
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.
Nat.Struct.Mol.Biol., 13, 2006
1AKH
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BU of 1akh by Molmil
MAT A1/ALPHA2/DNA TERNARY COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ...
著者Li, T, Jin, Y, Vershon, A.K, Wolberger, C.
登録日1997-05-19
公開日1998-05-20
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
1B72
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BU of 1b72 by Molmil
PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX
分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*AP*TP*GP*AP*TP*TP*GP*AP*TP*CP*GP*GP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*CP*CP*GP*AP*TP*CP*AP*AP*TP*CP*AP*TP*AP*GP*AP*G)-3'), PROTEIN (HOMEOBOX PROTEIN HOX-B1), ...
著者Piper, D.E, Batchelor, A.H, Chang, C.-P, Cleary, M.L, Wolberger, C.
登録日1999-01-27
公開日1999-02-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.
Cell(Cambridge,Mass.), 96, 1999
7UD5
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BU of 7ud5 by Molmil
Complex between MLL1-WRAD and an H2B-ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C.
登録日2022-03-18
公開日2022-09-21
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
8DU4
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BU of 8du4 by Molmil
Complex between RbBP5-WDR5 and an H2B-ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C.
登録日2022-07-26
公開日2022-09-21
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
6VEN
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BU of 6ven by Molmil
Yeast COMPASS in complex with a ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), COMPASS component BRE2, COMPASS component SDC1, ...
著者Worden, E.J, Wolberger, C.
登録日2020-01-02
公開日2020-01-15
最終更新日2020-01-22
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome.
Elife, 9, 2020
8T3Y
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BU of 8t3y by Molmil
Structure of Bre1-nucleosome complex - state1
分子名称: 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-08
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
8T3T
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BU of 8t3t by Molmil
Structure of Bre1-nucleosome complex - state3
分子名称: 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
8T3W
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BU of 8t3w by Molmil
Structure of Bre1-nucleosome complex - state2
分子名称: 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
4ZUX
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BU of 4zux by Molmil
SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Morgan, M, Wolberger, C.
登録日2015-05-17
公開日2016-02-24
最終更新日2016-03-09
実験手法X-RAY DIFFRACTION (3.82 Å)
主引用文献Structural basis for histone H2B deubiquitination by the SAGA DUB module.
Science, 351, 2016
1AWC
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BU of 1awc by Molmil
MOUSE GABP ALPHA/BETA DOMAIN BOUND TO DNA
分子名称: DNA (5'-D(*AP*AP*(BRU)P*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*AP*(CBR)P*AP*CP*(CBR)P*GP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*GP*GP*(BRU)P*GP*(BRU)P*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP*AP*T)-3'), PROTEIN (GA BINDING PROTEIN ALPHA), ...
著者Batchelor, A.H, Wolberger, C.
登録日1997-10-01
公開日1998-03-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA.
Science, 279, 1998
1ERJ
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BU of 1erj by Molmil
CRYSTAL STRUCTURE OF THE C-TERMINAL WD40 DOMAIN OF TUP1
分子名称: TRANSCRIPTIONAL REPRESSOR TUP1
著者Sprague, E.R, Redd, M.J, Johnson, A.D, Wolberger, C.
登録日2000-04-06
公開日2000-07-26
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast.
EMBO J., 19, 2000
6AQR
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BU of 6aqr by Molmil
SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin
分子名称: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ...
著者Morrow, M.E, Morgan, M.T, Wolberger, C.
登録日2017-08-21
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins.
EMBO Rep., 19, 2018
4LDT
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BU of 4ldt by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ...
著者Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C.
登録日2013-06-25
公開日2013-08-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat.Struct.Mol.Biol., 20, 2013
2O6V
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BU of 2o6v by Molmil
Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, Ubiquitin
著者Eddins, M.J, Wolberger, C.
登録日2006-12-08
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure and Solution NMR Studies of Lys48-linked Tetraubiquitin at Neutral pH
J.Mol.Biol., 367, 2007
8G6G
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BU of 8g6g by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 5
分子名称: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
8G6S
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BU of 8g6s by Molmil
H2AK119ub-modified nucleosome ubiquitin position 2
分子名称: 601 DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
8G6Q
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BU of 8g6q by Molmil
H2AK119ub-modified nucleosome ubiquitin position 1
分子名称: 601 DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
8G6H
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BU of 8g6h by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 6
分子名称: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published

 

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