4NIK
 
 | |
6ZWK
 | | Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody) | | 分子名称: | CHLORIDE ION, Histone H2AX, SODIUM ION, ... | | 著者 | McEwen, A.G, Moeglin, E, Desplancq, D, Weiss, E, Poterszman, A. | | 登録日 | 2020-07-28 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress.
Cancers (Basel), 13, 2021
|
|
6RZ5
 | | XFEL crystal structure of the human cysteinyl leukotriene receptor 1 in complex with zafirlukast | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Cysteinyl leukotriene receptor 1,Soluble cytochrome b562,Cysteinyl leukotriene receptor 1, OLEIC ACID, ... | | 著者 | Luginina, A, Gusach, A, Marin, E, Mishin, A, Brouillette, R, Popov, P, Shiryaeva, A, Besserer-Offroy, E, Longpre, J.M, Lyapina, E, Ishchenko, A, Patel, N, Polovinkin, V, Safronova, N, Bogorodskiy, A, Edelweiss, E, Liu, W, Batyuk, A, Gordeliy, V, Han, G.W, Sarret, P, Katritch, V, Borshchevskiy, V, Cherezov, V. | | 登録日 | 2019-06-12 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Sci Adv, 5, 2019
|
|
6RZ4
 | | Crystal structure of cysteinyl leukotriene receptor 1 in complex with pranlukast | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Cysteinyl leukotriene receptor 1,Soluble cytochrome b562,Cysteinyl leukotriene receptor 1, OLEIC ACID, ... | | 著者 | Luginina, A, Gusach, A, Marin, E, Mishin, A, Brouillette, R, Popov, P, Shiryaeva, A, Besserer-Offroy, E, Longpre, J.M, Lyapina, E, Ishchenko, A, Patel, N, Polovinkin, V, Safronova, N, Bogorodskiy, A, Edelweiss, E, Liu, W, Batyuk, A, Gordeliy, V, Han, G.W, Sarret, P, Katritch, V, Borshchevskiy, V, Cherezov, V. | | 登録日 | 2019-06-12 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Sci Adv, 5, 2019
|
|
2FK4
 | |
5NCL
 | | Crystal structure of the Cbk1-Mob2 kinase-coactivator complex with an SSD1 peptide | | 分子名称: | CBK1 kinase activator protein MOB2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein SSD1, ... | | 著者 | Gogl, G, Remenyi, A, Parker, B, Weiss, E. | | 登録日 | 2017-03-06 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface.
Biochemistry, 2020
|
|
5NCM
 | | Crystal structure Cbk1(NTR)-Mob2 complex | | 分子名称: | CBK1 kinase activator protein MOB2, Serine/threonine-protein kinase CBK1, ZINC ION | | 著者 | Gogl, G, Remenyi, A, Parker, B, Weiss, E. | | 登録日 | 2017-03-06 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface.
Biochemistry, 2020
|
|
6AW3
 | | Crystal structure of the HopQ-CEACAM3 L44Q complex | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 3, HopQ | | 著者 | Bonsor, D.A, Sundberg, E.J. | | 登録日 | 2017-09-05 | | 公開日 | 2018-05-16 | | 最終更新日 | 2018-07-11 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
|
|
6AW0
 | | Crystal structure of CEACAM3 L44Q | | 分子名称: | CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, ... | | 著者 | Bonsor, D.A, Sundberg, E.J. | | 登録日 | 2017-09-05 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
|
|
6AW1
 | | Crystal structure of CEACAM3 | | 分子名称: | CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Bonsor, D.A, Sundberg, E.J. | | 登録日 | 2017-09-05 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
|
|
6AW2
 | | Crystal structure of the HopQ-CEACAM1 complex | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, HopQ | | 著者 | Bonsor, D.A, Sundberg, E.J. | | 登録日 | 2017-09-05 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
|
|
6AVZ
 | | Crystal structure of the HopQ-CEACAM3 WT complex | | 分子名称: | CALCIUM ION, Carcinoembryonic antigen-related cell adhesion molecule 3, HopQ, ... | | 著者 | Bonsor, D.A, Sundberg, E.J. | | 登録日 | 2017-09-05 | | 公開日 | 2018-05-16 | | 最終更新日 | 2018-07-11 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA.
EMBO J., 37, 2018
|
|
1EI1
 | | DIMERIZATION OF E. COLI DNA GYRASE B PROVIDES A STRUCTURAL MECHANISM FOR ACTIVATING THE ATPASE CATALYTIC CENTER | | 分子名称: | DNA GYRASE B, GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Brino, L, Urzhumtsev, A, Oudet, P, Moras, D. | | 登録日 | 2000-02-23 | | 公開日 | 2000-03-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center.
J.Biol.Chem., 275, 2000
|
|
6FCM
 | | Crystal structure of human PCNA | | 分子名称: | Proliferating cell nuclear antigen | | 著者 | Housset, D, Frachet, P. | | 登録日 | 2017-12-20 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
|
|
6FCN
 | |
5NCN
 | | Crystal structure Dbf2(NTR)-Mob1 complex | | 分子名称: | CHLORIDE ION, Cell cycle protein kinase DBF2, DBF2 kinase activator protein MOB1, ... | | 著者 | Gogl, G, Remenyi, A, Parker, B, Weiss, E. | | 登録日 | 2017-03-06 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | | 主引用文献 | Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface.
Biochemistry, 2020
|
|
3UE8
 | | Kynurenine Aminotransferase II Inhibitors | | 分子名称: | (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ... | | 著者 | Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R. | | 登録日 | 2011-10-28 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett, 3, 2012
|
|
