2A3J
 
 | | Structure of URNdesign, a complete computational redesign of human U1A protein | | 分子名称: | U1 small nuclear ribonucleoprotein A | | 著者 | Varani, G, Dobson, N, Dantas, G, Baker, D. | | 登録日 | 2005-06-24 | | 公開日 | 2006-06-06 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-Resolution Structural Validation of the Computational Redesign of Human U1A Protein
Structure, 14, 2006
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1AUD
 | | U1A-UTRRNA, NMR, 31 STRUCTURES | | 分子名称: | RNA 3UTR, U1A 102 | | 著者 | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | 登録日 | 1997-08-22 | | 公開日 | 1998-02-25 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
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7VRL
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1ANR
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1ARJ
 | | ARG-BOUND TAR RNA, NMR | | 分子名称: | ARGININE, TAR RNA | | 著者 | Aboul-Ela, F, Varani, G, Karn, J. | | 登録日 | 1995-08-30 | | 公開日 | 1996-11-08 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.
J.Mol.Biol., 253, 1995
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1DZ5
 | | The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein | | 分子名称: | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | 著者 | Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. | | 登録日 | 2000-02-16 | | 公開日 | 2000-03-29 | | 最終更新日 | 2013-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
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1EI2
 | | STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS | | 分子名称: | NEOMYCIN, TAU EXON 10 SRE RNA | | 著者 | Varani, L, Spillantini, M.G, Goedert, M, Varani, G. | | 登録日 | 2000-02-23 | | 公開日 | 2000-03-06 | | 最終更新日 | 2017-02-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.
Nucleic Acids Res., 28, 2000
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6MXQ
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4M3O
 | | Crystal structure of K.lactis Rtr1 NTD | | 分子名称: | KLLA0F12672p, ZINC ION | | 著者 | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | | 登録日 | 2013-08-06 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
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7UMD
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7UMC
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7UME
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1QC8
 | | NMR STRUCTURE OF TAU EXON 10 SPLICING REGULATORY ELEMENT RNA | | 分子名称: | TAU EXON 10 SPLICING REGULATORY ELEMENT RNA | | 著者 | Varani, L, Spillantini, M.G, Klug, A, Goedert, M, Varani, G. | | 登録日 | 1999-05-18 | | 公開日 | 1999-08-31 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17.
Proc.Natl.Acad.Sci.USA, 96, 1999
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6NOA
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1UUD
 | | NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA | | 分子名称: | N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | | 著者 | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | | 登録日 | 2003-12-18 | | 公開日 | 2004-03-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
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1UUI
 | | NMR structure of a synthetic small molecule, rbt158, bound to HIV-1 TAR RNA | | 分子名称: | 4-[AMINO(IMINO)METHYL]-1-[2-(3-AMMONIOPROPOXY)-5-METHOXYBENZYL]PIPERAZIN-1-IUM, 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP* CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C)-3' | | 著者 | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | | 登録日 | 2003-12-19 | | 公開日 | 2004-02-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
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6PK9
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7SHX
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6U79
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6W3M
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7K4L
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2V3M
 | | Structure of the Gar1 domain of NAf1 | | 分子名称: | NAF1, SULFATE ION | | 著者 | Leulliot, N, Godin, K.S, Hoareau-Aveilla, C, Quevillon-Cheruel, S, Varani, G, Henry, Y, van Tilbeurgh, H. | | 登録日 | 2007-06-19 | | 公開日 | 2007-07-10 | | 最終更新日 | 2011-08-17 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | The Box H/Aca Rnp Assembly Factor Naf1P Contains a Domain Homologous to Gar1P Mediating its Interaction with Cbf5P.
J.Mol.Biol., 371, 2007
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3ZV0
 | | Structure of the SHQ1P-CBF5P complex | | 分子名称: | GLYCEROL, H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 4, PROTEIN SHQ1 | | 著者 | Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N. | | 登録日 | 2011-07-22 | | 公開日 | 2011-11-30 | | 最終更新日 | 2019-02-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
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3ZUZ
 | | Structure of Shq1p C-terminal domain | | 分子名称: | ISOPROPYL ALCOHOL, PROTEIN SHQ1 | | 著者 | Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N. | | 登録日 | 2011-07-22 | | 公開日 | 2011-11-30 | | 最終更新日 | 2019-02-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
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1HLX
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