8KE1
 
 | | PylRS C-terminus domain mutant bound with L-3-bromophenylalanine and AMPNP | | 分子名称: | 3-bromo-L-phenylalanine, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2023-08-11 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.50081539 Å) | | 主引用文献 | Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
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8KE3
 | | PylRS C-terminus domain mutant bound with D-3-trifluoromethylphenylalanine and AMPNP | | 分子名称: | (2R)-2-azanyl-3-[3-(trifluoromethyl)phenyl]propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2023-08-11 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.89980984 Å) | | 主引用文献 | Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
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8KE5
 | | PylRS C-terminus domain mutant bound with D-3-chlorophenylalanine and AMPNP | | 分子名称: | (2R)-2-azanyl-3-(3-chlorophenyl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2023-08-11 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.900073 Å) | | 主引用文献 | Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
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8KE6
 | | PylRS C-terminus domain mutant bound with L-3-chlorophenylalanine and AMPNP | | 分子名称: | 3-CHLORO-L-PHENYLALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2023-08-11 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.89570856 Å) | | 主引用文献 | Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids.
Front Genet, 14, 2023
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8K1K
 | | KtrA bound with ATP and sodium | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, SODIUM ION | | 著者 | Chiang, W.T, Chang, Y.K, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-07-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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8K1T
 | | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of MgCl2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-07-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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8K16
 | | KtrA bound with ATP and thallium | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, THALLIUM (I) ION | | 著者 | Chiang, W.T, Chang, Y.K, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-07-10 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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8K1U
 | | Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-07-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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8K1S
 | | Potassium transporter KtrAB from Bacillus subtilis in ADP-bound state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A, Ktr system potassium uptake protein B, ... | | 著者 | Chang, Y.K, Chiang, W.T, Hu, N.J, Tsai, M.D. | | 登録日 | 2023-07-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural basis and synergism of ATP and Na + activation in bacterial K + uptake system KtrAB.
Nat Commun, 15, 2024
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2AFF
 | | The solution structure of the Ki67FHA/hNIFK(226-269)3P complex | | 分子名称: | Antigen KI-67, MKI67 FHA domain interacting nucleolar phosphoprotein | | 著者 | Byeon, I.-J.L, Li, H, Song, H, Gronenborn, A.M, Tsai, M.D. | | 登録日 | 2005-07-25 | | 公開日 | 2005-10-25 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.
Nat.Struct.Mol.Biol., 12, 2005
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5XZW
 | | Crystal structure of Rad53 1-466 | | 分子名称: | Serine/threonine-protein kinase RAD53 | | 著者 | Weng, J.H, Tsai, M.D. | | 登録日 | 2017-07-14 | | 公開日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
Biochemistry, 56, 2017
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6KPE
 | | 343 K cryoEM structure of Sso-KARI in complex with Mg2+ | | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KQJ
 | | 309 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-18 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KOU
 | | 277 K cryoEM structure of Sso-KARI in complex with magnesium ions | | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KPI
 | | 298 K cryoEM structure of Sso-KARI in complex with Mg2+ | | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KQ4
 | | 323 K cryoEM structure of Sso-KARI in complex with Mg2+ | | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-16 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KPJ
 | | 298 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KPA
 | | 277 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KQ8
 | | 328 K cryoEM structure of Sso-KARI in complex with Mg2+ | | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-16 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KPH
 | | 343 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KQO
 | | 328 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-18 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KPK
 | | 309 K cryoEM structure of Sso-KARI in complex with Mg2+ | | 分子名称: | Ketol-acid reductoisomerase, MAGNESIUM ION | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6KQK
 | | 323 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ... | | 著者 | Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D. | | 登録日 | 2019-08-18 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.17 Å) | | 主引用文献 | Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
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6LY6
 | | PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP | | 分子名称: | MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2020-02-13 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5001328 Å) | | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
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1GH4
 | | Structure of the triple mutant (K56M, K120M, K121M) of phospholipase A2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2 | | 著者 | Sekar, K, Velmurugan, D, Tsai, M.D. | | 登録日 | 2000-11-09 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2.
J.Mol.Biol., 324, 2002
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