6CCY
| Crystal structure of Akt1 in complex with a selective inhibitor | 分子名称: | (5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one, RAC-alpha serine/threonine-protein kinase,PIFtide | 著者 | Wang, Y, Stout, S. | 登録日 | 2018-02-07 | 公開日 | 2018-05-02 | 最終更新日 | 2018-05-16 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT. Bioorg. Med. Chem. Lett., 28, 2018
|
|
1ZCT
| structure of glycogenin truncated at residue 270 in a complex with UDP | 分子名称: | Glycogenin-1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE | 著者 | Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J. | 登録日 | 2005-04-13 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Requirements for catalysis in mammalian glycogenin. J.Biol.Chem., 280, 2005
|
|
1ZDF
| Ser162 mutant of glycogenin complexed with UDP-glucose and manganese | 分子名称: | Glycogenin-1, MANGANESE (II) ION, SULFATE ION, ... | 著者 | Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J. | 登録日 | 2005-04-14 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Requirements for catalysis in mammalian glycogenin. J.Biol.Chem., 280, 2005
|
|
1ZCY
| apo form of a mutant of glycogenin in which Asp159 is replaced by Ser | 分子名称: | Glycogenin-1, SULFATE ION | 著者 | Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J. | 登録日 | 2005-04-13 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Requirements for catalysis in mammalian glycogenin. J.Biol.Chem., 280, 2005
|
|
1ZCU
| apo form of the 162S mutant of glycogenin | 分子名称: | Glycogenin-1 | 著者 | Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J. | 登録日 | 2005-04-13 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Requirements for catalysis in mammalian glycogenin. J.Biol.Chem., 280, 2005
|
|
1ZCV
| apo form of a mutant of glycogenin in which Asp159 is replaced by Asn | 分子名称: | Glycogenin-1, SULFATE ION | 著者 | Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J. | 登録日 | 2005-04-13 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Requirements for catalysis in mammalian glycogenin. J.Biol.Chem., 280, 2005
|
|
1ZDG
| Ser159 mutant of glycogenin complexed with UDP-glucose and manganese | 分子名称: | Glycogenin-1, MANGANESE (II) ION, SULFATE ION, ... | 著者 | Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J. | 登録日 | 2005-04-14 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Requirements for catalysis in mammalian glycogenin. J.Biol.Chem., 280, 2005
|
|