7RD1
| The Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25 | 分子名称: | Hexon protein, Hexon-interlacing protein, Penton protein, ... | 著者 | Baker, A.T, Boyd, R.J, Sarkar, D, Vermaas, J.V, Williams, D, Singharoy, A. | 登録日 | 2021-07-08 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Sci Adv, 7, 2021
|
|
6PNY
| X-ray Structure of Flpp3 | 分子名称: | Flpp3 | 著者 | Zook, J.D, Shekhar, M, Hansen, D.T, Conrad, C, Grant, T.D, Gupta, C, White, T, Barty, A, Basu, S, Zhao, Y, Zatsepin, N.A, Ishchenko, A, Batyuk, A, Gati, C, Li, C, Galli, L, Coe, J, Hunter, M, Liang, M, Weierstall, U, Nelson, G, James, D, Stauch, B, Craciunescu, F, Thifault, D, Liu, W, Cherezov, V, Singharoy, A, Fromme, P. | 登録日 | 2019-07-03 | 公開日 | 2020-02-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure, 28, 2020
|
|
4UTQ
| A structural model of the active ribosome-bound membrane protein insertase YidC | 分子名称: | ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC | 著者 | Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R. | 登録日 | 2014-07-22 | 公開日 | 2014-07-30 | 最終更新日 | 2018-10-03 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc. Elife, 3, 2014
|
|
7VW7
| Crystal structure of the 2 ADP-AlF4-bound V1 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Suzuki, K, Shekhar, M, Gupta, C, Singharoy, A, Murata, T. | 登録日 | 2021-11-09 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.818 Å) | 主引用文献 | Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations. Acs Cent.Sci., 8, 2022
|
|
5KTE
| Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter | 分子名称: | Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Bane, L.B, Gaudet, R, Weihofen, W.A, Singharoy, A. | 登録日 | 2016-07-11 | 公開日 | 2016-11-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.941 Å) | 主引用文献 | Crystal Structure and Conformational Change Mechanism of a Bacterial Nramp-Family Divalent Metal Transporter. Structure, 24, 2016
|
|
6M0R
| 2.7A Yeast Vo state3 | 分子名称: | (6~{E},10~{E},14~{E},18~{E},22~{E},26~{E},30~{R})-2,6,10,14,18,22,26,30-octamethyldotriaconta-2,6,10,14,18,22,26-heptaene, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, PYROPHOSPHATE, ... | 著者 | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, Singharoy, A, Chiu, W. | 登録日 | 2020-02-22 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex. Sci Adv, 6, 2020
|
|
6M0S
| 3.6A Yeast Vo state3 prime | 分子名称: | Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, vacuolar isoform, ... | 著者 | Roh, S.H, Shekhar, M, Pintilie, G, Chipot, C, Wilkens, S, SIngharoy, A, Chiu, W. | 登録日 | 2020-02-22 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM and MD infer water-mediated proton transport and autoinhibition mechanisms of V o complex. Sci Adv, 6, 2020
|
|
8FR7
| A hinge glycan regulates spike bending and impacts coronavirus infectivity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Pintilie, G, Wilson, E, Chmielewski, D, Schmid, M.F, Jin, J, Chen, M, Singharoy, A, Chiu, W. | 登録日 | 2023-01-06 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | A hinge glycan regulates spike bending and impacts coronavirus infectivity To Be Published
|
|
6PV6
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2019-07-19 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
|
|
7OP2
| Chadox1/ Chimpanzee adenovirus Y25 fiber knob protein | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Rizkallah, P.J, Baker, A.T, Parker, A.L, Teijeira Crespo, A, Lipka-Lloyd, M. | 登録日 | 2021-05-28 | 公開日 | 2021-06-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Sci Adv, 7, 2021
|
|
7JMJ
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 37 - State 5 (S5) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2020-07-31 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
|
|
7JMI
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 29 - State 3 (S3) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2020-07-31 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
|
|
7JMG
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 22 - State 2 (S2) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2020-07-31 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
|
|
7JMF
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 42 - State 6 (S6) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2020-07-31 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
|
|
7JMH
| Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 35 - State 4 (S4) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | 登録日 | 2020-07-31 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
|
|
6D9W
| Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter, in the inward-open apo state | 分子名称: | Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Gaudet, R, Bane, L.B, Weihofen, W.A, Singharoy, A, Zimanyi, C.M, Bozzi, A.T. | 登録日 | 2018-04-30 | 公開日 | 2019-02-13 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (3.941 Å) | 主引用文献 | Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter. Elife, 8, 2019
|
|
4G7Y
| |
4G80
| |
4G7V
| |
8E6L
| X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter D296A mutant in an inward-open, manganese-bound state | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Divalent metal cation transporter MntH, ... | 著者 | Ray, S, Gaudet, R. | 登録日 | 2022-08-22 | 公開日 | 2023-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter. Elife, 12, 2023
|
|
8E5S
| |
8E6H
| X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter A47W mutant in an occluded, manganese-bound state | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Ray, S, Gaudet, R. | 登録日 | 2022-08-22 | 公開日 | 2023-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter. Elife, 12, 2023
|
|
8E6N
| X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter G223W mutant in an outward-open, manganese-bound state | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Divalent metal cation transporter MntH, ... | 著者 | Bozzi, A.T, Ray, S, Zimanyi, C.M, Nicoludis, J.M, Gaudet, R. | 登録日 | 2022-08-22 | 公開日 | 2023-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter. Elife, 12, 2023
|
|
8E6M
| X-ray structure of the Deinococcus radiodurans Nramp/MntH divalent transition metal transporter WT in an inward-open, cadmium-bound state | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CADMIUM ION, CHLORIDE ION, ... | 著者 | Ray, S, Gaudet, R. | 登録日 | 2022-08-22 | 公開日 | 2023-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | High-resolution structures with bound Mn 2+ and Cd 2+ map the metal import pathway in an Nramp transporter. Elife, 12, 2023
|
|
8E5V
| |