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STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:	Daopin, S, Matthews, B.W.
Deposit date:	1991-01-28
Release date:	1991-10-15
Last modified:	2022-11-23
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991

1L51

STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME
Descriptor:	T4 LYSOZYME
Authors:	Daopin, S, Matthews, B.W.
Deposit date:	1991-01-28
Release date:	1991-10-15
Last modified:	2022-11-23
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991

1L60

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor:	T4 LYSOZYME
Authors:	Nicholson, H, Matthews, B.W.
Deposit date:	1991-05-06
Release date:	1991-10-15
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers, 32, 1992

1L74

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Zhang, X, Matthews, B.W.
Deposit date:	1991-09-23
Release date:	1991-10-15
Last modified:	2020-07-22
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L03

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:	Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W.
Deposit date:	1988-02-05
Release date:	1988-04-16
Last modified:	2022-11-23
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L32

REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY
Descriptor:	T4 LYSOZYME
Authors:	Bell, J.A, Dao-Pin, S, Matthews, B.W.
Deposit date:	1989-05-01
Release date:	1990-01-15
Last modified:	2022-11-23
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability. Science, 239, 1988

1L37

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
Descriptor:	T4 LYSOZYME
Authors:	Daopin, S, Matthews, B.W.
Deposit date:	1991-01-28
Release date:	1991-10-15
Last modified:	2022-11-23
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L56

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:	Nicholson, H, Matthews, B.W.
Deposit date:	1991-05-06
Release date:	1991-10-15
Last modified:	2017-11-29
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme. Biopolymers, 32, 1992

7RFQ

STRUCTURE OF BACTERIAL SYLF DOMAIN CONTAINING PROTEIN, BETA CELL EXPANSION FACTOR A (BEFA)
Descriptor:	BETA CELL EXPANSION FACTOR A (BEFA), CITRIC ACID
Authors:	Sweeney, E.G.
Deposit date:	2021-07-14
Release date:	2022-07-20
Last modified:	2022-11-09
Method:	X-RAY DIFFRACTION (1.27 Å)
Cite:	BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases beta cell mass. Cell Metab., 34, 2022

1L58

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
Authors:	Nicholson, H, Matthews, B.W.
Deposit date:	1991-05-06
Release date:	1991-10-15
Last modified:	2017-11-29
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	To be Published

1L64

TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Heinz, D, Matthews, B.W.
Deposit date:	1991-09-23
Release date:	1991-10-15
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc.Natl.Acad.Sci.USA, 89, 1992

1L63

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Nicholson, H, Matthews, B.W.
Deposit date:	1991-05-06
Release date:	1991-10-15
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L55

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:	Nicholson, H, Matthews, B.W.
Deposit date:	1991-05-06
Release date:	1991-10-15
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

3CBE

Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments
Descriptor:	Green fluorescent protein, MAGNESIUM ION
Authors:	Lohman, J.R.
Deposit date:	2008-02-21
Release date:	2008-08-19
Last modified:	2021-10-20
Method:	X-RAY DIFFRACTION (1.488 Å)
Cite:	Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments Biochemistry, 47, 2008

3CD9

Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments
Descriptor:	Green fluorescent protein
Authors:	Lohman, J.R.
Deposit date:	2008-02-26
Release date:	2008-08-19
Last modified:	2021-10-20
Method:	X-RAY DIFFRACTION (1.502 Å)
Cite:	Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments Biochemistry, 47, 2008

3CB9

Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments
Descriptor:	Green fluorescent protein, MAGNESIUM ION
Authors:	Lohman, J.R.
Deposit date:	2008-02-21
Release date:	2008-08-19
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.31 Å)
Cite:	Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments Biochemistry, 47, 2008

3CV1

Atomic Resolution Structures of Escherichia coli and Bacillis anthracis Malate Synthase A: Comparison with Isoform G and Implications for Structure Based Drug Design
Descriptor:	ACETATE ION, CALCIUM ION, GLYCEROL, ...
Authors:	Lohman, J.R.
Deposit date:	2008-04-17
Release date:	2008-11-11
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	Atomic resolution structures of Escherichia coli and Bacillus anthracis malate synthase A: comparison with isoform G and implications for structure-based drug discovery Protein Sci., 17, 2008

3CD1

Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments
Descriptor:	Green fluorescent protein
Authors:	Lohman, J.R.
Deposit date:	2008-02-26
Release date:	2008-08-19
Last modified:	2021-10-20
Method:	X-RAY DIFFRACTION (1.312 Å)
Cite:	Development of a family of redox-sensitive green fluorescent protein indicators for use in relatively oxidizing subcellular environments Biochemistry, 47, 2008

1EMB

GREEN FLUORESCENT PROTEIN (GFP) FROM AEQUOREA VICTORIA, GLN 80 REPLACED WITH ARG
Descriptor:	GREEN FLUORESCENT PROTEIN
Authors:	Brejc, K, Sixma, T.
Deposit date:	1997-01-08
Release date:	1997-06-16
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.13 Å)
Cite:	Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein. Proc.Natl.Acad.Sci.USA, 94, 1997

6B7L

Aeromonas veronii immune modulator A
Descriptor:	CHLORIDE ION, FORMIC ACID, immune modulator A
Authors:	Sweeney, E.S, Remington, S.J, Perkins, A.
Deposit date:	2017-10-04
Release date:	2018-10-03
Last modified:	2022-03-23
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	A bacterial immunomodulatory protein with lipocalin-like domains facilitates host-bacteria mutualism in larval zebrafish. Elife, 7, 2018

3HTC

THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN
Descriptor:	ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2
Authors:	Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W.
Deposit date:	1993-06-11
Release date:	1994-01-31
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249, 1990

4BCL

FMO protein from Prosthecochloris aestuarii 2K at Room Temperature
Descriptor:	BACTERIOCHLOROPHYLL A, BACTERIOCHLOROPHYLL A PROTEIN
Authors:	Tronrud, D.E, Matthews, B.W.
Deposit date:	1998-04-17
Release date:	1998-09-16
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Refinement of the Structure of a Water-Soluble Antenna Complex from Green Photosynthetic Bacteria by Incorporation of the Chemically Determined Amino Acid Sequence Photosynthetic Reaction Center, 1, 1993

1PTD

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Descriptor:	PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Authors:	Heinz, D.W, Ryan, M, Bullock, T.L, Griffith, O.H.
Deposit date:	1995-05-24
Release date:	1996-07-11
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal structure of the phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with myo-inositol. EMBO J., 14, 1995

1PTG

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN COMPLEX WITH MYO-INOSITOL
Descriptor:	1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Authors:	Heinz, D.W, Ryan, M, Bullock, T.L, Griffith, O.H.
Deposit date:	1995-05-24
Release date:	1996-07-11
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal structure of the phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with myo-inositol. EMBO J., 14, 1995

2OKW

A non-invasive GFP-based biosensor for mercury ions
Descriptor:	Green fluorescent protein
Authors:	Chapleau, R.R, Blomberg, R, Ford, P.C, Sagermann, M.
Deposit date:	2007-01-17
Release date:	2007-12-04
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Design of a highly specific and noninvasive biosensor suitable for real-time in vivo imaging of mercury (II) uptake. Protein Sci., 17, 2008

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