2BUF
| Arginine Feed-Back Inhibitable Acetylglutamate Kinase | 分子名称: | ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Ramon-Maiques, S, Fernandez-Murga, M.L, Vagin, A, Fita, I, Rubio, V. | 登録日 | 2005-06-12 | 公開日 | 2005-12-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Bases of Feed-Back Control of Arginine Biosynthesis, Revealed by the Structure of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga Maritima and Pseudomonas Aeruginosa J.Mol.Biol., 356, 2006
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1E19
| Structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic archaeon Pyrococcus furiosus bound to ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CARBAMATE KINASE, MAGNESIUM ION | 著者 | Ramon-Maiques, S, Marina, A, Uriarte, M, Fita, I, Rubio, V. | 登録日 | 2000-04-28 | 公開日 | 2000-07-04 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The 1.5-A Resolution Crystal Structure of the Carbamate Kinase-Like Carbamoyl Phosphate Synthetase from the Hyperthermophilic Archaeon Pyrococcus Furiosus, Bound to Adp, Confirms that This Thermoestable Enzyme is a Carbamate Kinase, and Provides Insights Into Substrate Binding and Stability in Carbamate Kinases J.Mol.Biol., 299, 2000
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1GS5
| N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP | 分子名称: | ACETYLGLUTAMATE KINASE, MAGNESIUM ION, N-ACETYL-L-GLUTAMATE, ... | 著者 | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Fita, I, Rubio, V. | 登録日 | 2001-12-28 | 公開日 | 2002-05-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of Acetylglutamate Kinase, a Key Enzyme for Arginine Biosynthesis and a Prototype for the Amino Acid Kinase Enzyme Family, During Catalysis Structure, 10, 2002
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1GSJ
| Selenomethionine substituted N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate n-acetyl-L-glutamate and its substrate analog AMPPNP | 分子名称: | ACETYLGLUTAMATE KINASE, MAGNESIUM ION, N-ACETYL-L-GLUTAMATE, ... | 著者 | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Fita, I, Rubio, V. | 登録日 | 2002-01-07 | 公開日 | 2002-05-16 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of Acetylglutamate Kinase, a Key Enzyme for Arginine Biosynthesis and a Prototype for the Amino Acid Kinase Enzyme Family, During Catalysis Structure, 10, 2002
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2V87
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2V83
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2V85
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2V88
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2V86
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2WE4
| Carbamate kinase from Enterococcus faecalis bound to a sulfate ion and two water molecules, which mimic the substrate carbamyl phosphate | 分子名称: | CARBAMATE KINASE 1, SULFATE ION | 著者 | Ramon-Maiques, S, Marina, A, Gil-Ortiz, F, Rubio, V. | 登録日 | 2009-03-27 | 公開日 | 2010-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site-Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria. J.Mol.Biol., 397, 2010
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2WE5
| Carbamate kinase from Enterococcus faecalis bound to MgADP | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CARBAMATE KINASE 1, ... | 著者 | Ramon-Maiques, S, Marina, A, Rubio, V. | 登録日 | 2009-03-27 | 公開日 | 2010-03-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Substrate Binding and Catalysis in Carbamate Kinase Ascertained by Crystallographic and Site- Directed Mutagenesis Studies. Movements and Significance of a Unique Globular Subdomain of This Key Enzyme for Fermentative ATP Production in Bacteria. J.Mol.Biol., 397, 2010
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5NNL
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2V89
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7O0C
| Human phosphomannomutase 2 (PMM2) wild-type in apo state | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Phosphomannomutase 2, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-03-26 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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7O4G
| Human phosphomannomutase 2 (PMM2) wild-type soaked with the activator glucose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-04-06 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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7O1B
| Human phosphomannomutase 2 (PMM2) wild-type co-crystallized with the activator glucose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-03-29 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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7O5Z
| Human phosphomannomutase 2 (PMM2) with mutation T237M in apo state | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-04-09 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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7O58
| Human phosphomannomutase 2 (PMM2) with mutation T237M in complex with the activator glucose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Ramon-Maiques, S, Briso-Montiano, A, Del Cano-Ochoa, F, Vilas, A, Perez, B, Rubio, V. | 登録日 | 2021-04-08 | 公開日 | 2022-02-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45, 2022
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2WXB
| Acetylglutamate kinase from Escherichia coli free of substrates | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Ramon-Maiques, S, Gil-Ortiz, F, Rubio, V. | 登録日 | 2009-11-06 | 公開日 | 2010-05-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Two Crystal Structures of Escherichia Coli N-Acetyl-L-Glutamate Kinase Demonstrate the Cycling between Open and Closed Conformations. J.Mol.Biol., 399, 2010
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6HFF
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6HFQ
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6HFI
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6HFJ
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6HFS
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6HFE
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