7OIQ
 
 | | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) | | 分子名称: | AP-2 complex subunit mu, F-BAR domain only protein 2 | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-12 | | 公開日 | 2022-06-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OFP
 | | Apo Structure of Mu2 Adaptin Subunit (Ap50) Of AP2 Clathrin Adaptor | | 分子名称: | AP-2 complex subunit mu, CITRIC ACID, GLYCEROL | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-05 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OHO
 | | Crystal structure of AP2 FCHO2 chimera | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-11 | | 公開日 | 2022-06-01 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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8QQF
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6YAE
 | | AP2 core in physiological buffer | | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G. | | 登録日 | 2020-03-12 | | 公開日 | 2020-07-29 | | 最終更新日 | 2020-08-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
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7BLR
 | | Vps35/Vps29 arch of fungal membrane-assembled retromer:Vps5 (SNX-BAR) complex. | | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | 登録日 | 2021-01-18 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7BLN
 | | VPS35/VPS29 arch of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins | | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | 登録日 | 2021-01-18 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7BLP
 | | Vps35/Vps29 arch of fungal membrane-assembled retromer:Grd19 complex | | 分子名称: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35 | | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | 登録日 | 2021-01-18 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7BLO
 | | VPS26 dimer region of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins | | 分子名称: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, C-term (residues 493-54) of Wls (fitted sequence corresponds to hDMT1-II), Sorting nexin-3, ... | | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | 登録日 | 2021-01-18 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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7BLQ
 | | Vps26 dimer region of the fungal membrane-assembled retromer:Grd19 complex. | | 分子名称: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Sorting nexin-3, The C-terminal portion of Kex2 cargo, ... | | 著者 | Leneva, N, Kovtun, O, Morado, D.R, Briggs, J.A.G, Owen, D.J. | | 登録日 | 2021-01-18 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (9.2 Å) | | 主引用文献 | Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly.
Sci Adv, 7, 2021
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3I2W
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6QH5
 | | AP2 clathrin adaptor mu2T156-phosphorylated core in closed conformation | | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | | 登録日 | 2019-01-15 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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6QH6
 | | AP2 clathrin adaptor core with two cargo peptides in open+ conformation | | 分子名称: | AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | | 登録日 | 2019-01-15 | | 公開日 | 2019-09-04 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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6QH7
 | | AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation | | 分子名称: | ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ... | | 著者 | Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R. | | 登録日 | 2019-01-15 | | 公開日 | 2019-09-04 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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2PHK
 | | THE CRYSTAL STRUCTURE OF A PHOSPHORYLASE KINASE PEPTIDE SUBSTRATE COMPLEX: KINASE SUBSTRATE RECOGNITION | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Lowe, E.D, Noble, M.E.M, Skamnaki, V.T, Oikonomakos, N.G, Owen, D.J, Johnson, L.N. | | 登録日 | 1998-06-18 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.
EMBO J., 16, 1997
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4CCA
 | | Structure of human Munc18-2 | | 分子名称: | CHLORIDE ION, SYNTAXIN-BINDING PROTEIN 2 | | 著者 | Hackmann, Y, Graham, S.C, Ehl, S, Hoening, S, Lehmberg, K, Arico, M, Owen, D.J, Griffiths, G.G. | | 登録日 | 2013-10-21 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Syntaxin Binding Mechanism and Disease-Causing Mutations in Munc18-2
Proc.Natl.Acad.Sci.USA, 110, 2013
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4BX9
 | | Human Vps33A in complex with a fragment of human Vps16 | | 分子名称: | (2S)-2-hydroxybutanedioic acid, FORMIC ACID, MALONIC ACID, ... | | 著者 | Graham, S.C, Wartosch, L, Gray, S.R, Scourfield, E.J, Deane, J.E, Luzio, J.P, Owen, D.J. | | 登録日 | 2013-07-09 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.
Proc. Natl. Acad. Sci. U.S.A., 110, 2013
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4CYM
 | | Complex of human VARP-ANKRD1 with Rab32-GppCp | | 分子名称: | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R. | | 登録日 | 2014-04-13 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Dev.Cell, 29, 2014
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4CZ2
 | | Complex of human VARP-ANKRD1 with Rab32-GppCp. Selenomet derivative. | | 分子名称: | ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Perez-Dorado, I, Schaefer, I.B, McCoy, A.J, Owen, D.J, Evans, P.R. | | 登録日 | 2014-04-16 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Varp is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface.
Dev.Cell, 29, 2014
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2QYW
 | | Crystal structure of mouse vti1b Habc domain | | 分子名称: | Vesicle transport through interaction with t-SNAREs 1B homolog | | 著者 | Miller, S.E, Collins, B.M, McCoy, A.J, Robinson, M.S, Owen, D.J. | | 登録日 | 2007-08-15 | | 公開日 | 2007-11-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Nature, 450, 2007
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2QY7
 | | Crystal structure of human epsinR ENTH domain | | 分子名称: | Clathrin interactor 1 | | 著者 | Miller, S.E, Collins, B.M, McCoy, A.J, Robinson, M.S, Owen, D.J. | | 登録日 | 2007-08-13 | | 公開日 | 2007-11-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Nature, 450, 2007
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2VX8
 | | Vamp7 longin domain Hrb peptide complex | | 分子名称: | CHLORIDE ION, NUCLEOPORIN-LIKE PROTEIN RIP, VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 | | 著者 | Evans, P.R, Owen, D.J, Luzio, J.P. | | 登録日 | 2008-07-01 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular Basis for the Sorting of the Snare Vamp7 Into Endocytic Clathrin-Coated Vesicles by the Arfgap Hrb.
Cell(Cambridge,Mass.), 134, 2008
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2XA7
 | | AP2 clathrin adaptor core in active complex with cargo peptides | | 分子名称: | ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ... | | 著者 | Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J. | | 登録日 | 2010-03-29 | | 公開日 | 2010-07-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
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1NAF
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1NA8
 | | Crystal structure of ADP-ribosylation factor binding protein GGA1 | | 分子名称: | ADP-ribosylation factor binding protein GGA1 | | 著者 | Lui, W.W, Collins, B.M, Hirst, J, Motley, A, Millar, C, Schu, P, Owen, D.J, Robinson, M.S. | | 登録日 | 2002-11-27 | | 公開日 | 2003-07-29 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin
Mol.Cell.Biol., 14, 2003
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