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2V7J
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BU of 2v7j by Molmil
PrnB L-tryptophan complex
Descriptor: PRNB, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Naismith, J.H.
Deposit date:2007-07-30
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway is Related to the Heme-Dependent Dioxygenase Superfamily
Biochemistry, 46, 2007
2VG4
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BU of 2vg4 by Molmil
Rv2361 native
Descriptor: UNDECAPRENYL PYROPHOSPHATE SYNTHETASE
Authors:Naismith, J.H, Wang, W, Dong, C.
Deposit date:2007-11-08
Release date:2007-11-27
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
2V82
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BU of 2v82 by Molmil
KDPGal complexed to KDPGal
Descriptor: 2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE, 2-KETO-DEOXY-GALACTOSE
Authors:Naismith, J.H.
Deposit date:2007-08-02
Release date:2007-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization and crystal structure of Escherichia coli KDPGal aldolase.
Bioorg. Med. Chem., 16, 2008
2VFW
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BU of 2vfw by Molmil
Rv1086 native
Descriptor: SHORT-CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHETASE, SULFATE ION
Authors:Naismith, J.H, Wang, W, Dong, C.
Deposit date:2007-11-05
Release date:2007-11-13
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
2VG1
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BU of 2vg1 by Molmil
Rv1086 E,E-farnesyl diphosphate complex
Descriptor: FARNESYL DIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
Authors:Naismith, J.H, Wang, W, Dong, C.
Deposit date:2007-11-07
Release date:2007-11-13
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
2V7L
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BU of 2v7l by Molmil
PrnB 7Cl-L-tryptophan complex
Descriptor: 7-CHLOROTRYPTOPHAN, PRNB, PROTOPORPHYRIN IX CONTAINING FE
Authors:Naismith, J.H.
Deposit date:2007-07-30
Release date:2007-08-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway is Related to the Heme-Dependent Dioxygenase Superfamily.
Biochemistry, 46, 2007
2V7M
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BU of 2v7m by Molmil
PrnB 7-Cl-D-tryptophan complex
Descriptor: 7-CL-D-TRYPTOPHAN, PHOSPHATE ION, PRNB, ...
Authors:Naismith, J.H.
Deposit date:2007-07-30
Release date:2007-08-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Second Enzyme in Pyrrolnitrin Biosynthetic Pathway is Related to the Heme-Dependent Dioxygenase Superfamily
Biochemistry, 46, 2007
2XUV
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BU of 2xuv by Molmil
The structure of HdeB
Descriptor: HDEB, SULFATE ION
Authors:Naismith, J.H, Wang, W.
Deposit date:2010-10-21
Release date:2011-08-24
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Salt Bridges Regulate Both Dimer Formation and Monomeric Flexibility in Hdeb and May Have a Role in Periplasmic Chaperone Function.
J.Mol.Biol., 415, 2012
1BXH
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BU of 1bxh by Molmil
CONCANAVALIN A COMPLEXED TO METHYL ALPHA1-2 MANNOBIOSIDE
Descriptor: CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ...
Authors:Moothoo, D.N, Canaan, B, Field, R.A, Naismith, J.H.
Deposit date:1998-10-02
Release date:1998-10-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition.
Glycobiology, 9, 1999
8C0E
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BU of 8c0e by Molmil
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase Wzz form a complex in vivo and in vitro
Descriptor: ECA polysaccharide chain length modulation protein
Authors:Weckener, M, Woodward, L.S, Clarke, B.R, Liu, H, Ward, P.N, Le Bas, A, Bhella, D, Whitfield, C, Naismith, J.H.
Deposit date:2022-12-16
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex.
Open Biology, 13, 2023
8BJZ
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BU of 8bjz by Molmil
crystal structure of antibody Fab with SiaLac-amidine-Lys
Descriptor: (2~{S})-2-acetamido-6-(2-sulfanylethanimidoylamino)hexanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BAR-1 Fab heavy chain, ...
Authors:Moynie, L, Naismith, J.H.
Deposit date:2022-11-08
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:crystal structure of antibody Fab with SiaLac-amidine-Lys
To Be Published
8BSO
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BU of 8bso by Molmil
crystal structure of antibody Fab with SiaLac-amidine-Lys
Descriptor: (2~{S})-2-acetamido-6-(2-sulfanylethanimidoylamino)hexanamide, BAR-1 Fab heavy chain, BAR-1 Fab light chain, ...
Authors:Moynie, L, Naismith, J.H.
Deposit date:2022-11-25
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:crystal structure of antibody Fab with SiaLac-amidine-Lys
To Be Published
4UVQ
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BU of 4uvq by Molmil
PatG Domain of Unknown Function
Descriptor: THIAZOLINE OXIDASE/SUBTILISIN-LIKE PROTEASE, ZINC ION
Authors:Mann, G, Koehnke, J, Bent, A.F, Graham, R, Schwarz-Linek, U, Naismith, J.H.
Deposit date:2014-08-07
Release date:2014-09-17
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.724 Å)
Cite:The Structure of the Cyanobactin Domain of Unknown Function from Patg in the Patellamide Gene Cluster
Acta Crystallogr.,Sect.F, 70, 2014
4V1V
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BU of 4v1v by Molmil
Heterocyclase in complex with substrate and Cofactor
Descriptor: LYND, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Koehnke, J, Naismith, J.H.
Deposit date:2014-10-02
Release date:2015-01-14
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural Analysis of Leader Peptide Binding Enables Leader-Free Cyanobactin Processing.
Nat.Chem.Biol., 11, 2015
4V1T
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BU of 4v1t by Molmil
Heterocyclase in complex with substrate and Cofactor
Descriptor: ADENOSINE-5'-DIPHOSPHATE, LYND, MAGNESIUM ION, ...
Authors:Koehnke, J, Naismith, J.H.
Deposit date:2014-10-02
Release date:2015-01-14
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural Analysis of Leader Peptide Binding Enables Leader-Free Cyanobactin Processing
Nat.Chem.Biol., 11, 2015
4UW0
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BU of 4uw0 by Molmil
Low resolution structure of WbdD with C-terminal bundle ordered to residue 505
Descriptor: S-ADENOSYLMETHIONINE, WBDD
Authors:Hagelueken, G, Huang, H, Naismith, J.H.
Deposit date:2014-08-08
Release date:2014-08-27
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (3.87 Å)
Cite:A Coiled-Coil Domain Acts as a Molecular Ruler to Regulate O-Antigen Chain Length in Lipopolysaccharide.
Nat.Struct.Mol.Biol., 22, 2015
4UDS
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BU of 4uds by Molmil
Crystal structure of MbdR regulator from Azoarcus sp. CIB
Descriptor: MBDR REGULATOR
Authors:Liu, H, Liu, H.X, MacMahon, S.A, Juarez, J.F, Zamarro, M.T, Eberlein, C, Boll, M, Carmona, M, Diaz, E, Naismith, J.H.
Deposit date:2014-12-11
Release date:2014-12-24
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Unraveling the Specific Regulation of the Mbd Central Pathway for the Anaerobic Degradation of 3-Methylbenzoate.
J.Biol.Chem., 290, 2015
4V1U
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BU of 4v1u by Molmil
Heterocyclase in complex with substrate and Cofactor
Descriptor: ADENOSINE MONOPHOSPHATE, CALCIUM ION, LYND, ...
Authors:Koehnke, J, Naismith, J.H.
Deposit date:2014-10-02
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural Analysis of Leader Peptide Binding Enables Leader-Free Cyanobactin Processing.
Nat.Chem.Biol., 11, 2015
3FFE
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BU of 3ffe by Molmil
Structure of Achromobactin Synthetase Protein D, (AcsD)
Descriptor: AcsD
Authors:McMahon, S.A, Liu, H, Carter, L, Oke, M, Johnson, K.A, Schmelz, S, Challis, G.L, White, M.F, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF)
Deposit date:2008-12-03
Release date:2009-02-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis
Nat.Chem.Biol., 5, 2009
3TEK
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BU of 3tek by Molmil
ThermoDBP: a non-canonical single-stranded DNA binding protein with a novel structure and mechanism
Descriptor: ThermoDBP-single stranded DNA binding protein
Authors:White, M.F, Paytubi, S, Liu, H, Graham, S, McMahon, S.A, Naismith, J.H.
Deposit date:2011-08-15
Release date:2011-11-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales.
Proc.Natl.Acad.Sci.USA, 109, 2012
5AIT
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BU of 5ait by Molmil
A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink)
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 N, ...
Authors:Branigan, E, Naismith, J.H.
Deposit date:2015-02-17
Release date:2015-07-08
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains
Nat.Struct.Mol.Biol., 22, 2015
5AIU
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BU of 5aiu by Molmil
A complex of RNF4-RING domain, Ubc13-Ub (isopeptide crosslink)
Descriptor: 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE RNF4, POLYUBIQUITIN-C, ...
Authors:Branigan, E, Naismith, J.H.
Deposit date:2015-02-17
Release date:2015-07-08
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Basis for the Ring Catalyzed Synthesis of K63 Linked Ubiquitin Chains
Nat.Struct.Mol.Biol., 22, 2015
3ZFV
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BU of 3zfv by Molmil
Crystal structure of an archaeal CRISPR-associated Cas6 nuclease
Descriptor: CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1, GLYCEROL
Authors:Reeks, J, Liu, H, White, M.F, Naismith, J.H.
Deposit date:2012-12-12
Release date:2013-04-03
Last modified:2013-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Dimeric Crenarchaeal Cas6 Enzyme with an Atypical Active Site for Crispr RNA Processing
Biochem.J., 452, 2013
3ZC4
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BU of 3zc4 by Molmil
The structure of Csa5 from Sulfolobus solfataricus.
Descriptor: DI(HYDROXYETHYL)ETHER, SSO1398
Authors:Reeks, J, Anderson, L, White, M.F, Naismith, J.H.
Deposit date:2012-11-15
Release date:2013-02-20
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structure of the Archaeal Cascade Subunit Csa5: Relating the Small Subunits of Crispr Effector Complexes.
RNA Biol., 10, 2013
5O3X
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BU of 5o3x by Molmil
Structural characterization of the fast and promiscuous macrocyclase from plant - apo PCY1
Descriptor: CACODYLATE ION, Peptide cyclase 1
Authors:Ludewig, H, Czekster, C.M, Bent, A.F, Naismith, J.H.
Deposit date:2017-05-25
Release date:2018-02-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Characterization of the Fast and Promiscuous Macrocyclase from Plant PCY1 Enables the Use of Simple Substrates.
ACS Chem. Biol., 13, 2018

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