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8DLF
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BU of 8dlf by Molmil
EBNA1 DNA binding domain (DBD) (458-617)+2 repeats of family repeat (FR) region
分子名称: 2XFR DNA (56-MER), Epstein-Barr nuclear antigen 1
著者Mei, Y, Lieberman, P.M, Murakami, K.
登録日2022-07-07
公開日2023-05-17
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM Structure and Functional Studies of EBNA1 Binding to the Family of Repeats and Dyad Symmetry Elements of Epstein-Barr Virus oriP.
J.Virol., 96, 2022
6VH6
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BU of 6vh6 by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragment
分子名称: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Epstein-Barr nuclear antigen 1
著者Messick, T.E, Lieberman, P.M.
登録日2020-01-09
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.
Molecules, 25, 2020
5T7X
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BU of 5t7x by Molmil
Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA
分子名称: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1
著者Malecka, K.A, Messick, T.E, Lieberman, P.M.
登録日2016-09-06
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Oncotarget, 8, 2017
6PW2
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BU of 6pw2 by Molmil
Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication
分子名称: DNA (62-MER), DNA (62-MER) complementary DNA strand, Epstein-Barr nuclear antigen 1
著者Messick, T.E, Malecka, K.A, Lieberman, P.M.
登録日2019-07-22
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
J.Virol., 93, 2019
5KDM
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BU of 5kdm by Molmil
Crystal structure of EBV tegument protein BNRF1 in complex with histone chaperone DAXX and histones H3.3-H4
分子名称: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
著者Huang, H, Patel, D.
登録日2016-06-08
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis underlying viral hijacking of a histone chaperone complex.
Nat Commun, 7, 2016
4K2J
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BU of 4k2j by Molmil
Decameric ring structure of KSHV (HHV-8) latency-associated nuclear antigen (LANA) DNA binding domain
分子名称: CHLORIDE ION, FORMIC ACID, KSHV (HHV-8) latency-associated nuclear antigen (LANA)
著者Domsic, J.F, Marmorstein, R.
登録日2013-04-09
公開日2013-11-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANA.
Plos Pathog., 9, 2013
5W2L
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BU of 5w2l by Molmil
Structure of a central domain of human Ctc1
分子名称: CST complex subunit CTC1, MERCURY (II) ION
著者Rice, C, Skordalakes, E.
登録日2017-06-06
公開日2017-11-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.
Nucleic Acids Res., 46, 2018
5WMF
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BU of 5wmf by Molmil
Crystal structure of the Hexameric Ring of Epstein-Barr Virus Nuclear Antigen-1, EBNA1
分子名称: Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2017-07-28
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance.
J. Virol., 91, 2017
6NPP
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Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
分子名称: 3-(phenylethynyl)-2-(1H-pyrrol-1-yl)benzoic acid, EBNA1, Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2019-01-18
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
6NPM
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BU of 6npm by Molmil
Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
分子名称: 5-(phenylethynyl)pyridine-3-carboxylic acid, Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2019-01-17
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019
6NPI
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Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragments
分子名称: ({2-[(4-bromo-5-methyl-1,2-oxazol-3-yl)amino]-2-oxoethyl}sulfanyl)acetic acid, 2-pyrrol-1-ylbenzoic acid, Epstein-Barr nuclear antigen 1
著者Messick, T.E.
登録日2019-01-17
公開日2019-03-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth.
Sci Transl Med, 11, 2019

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件を2024-04-24に公開中

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