6HSR
 
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6HSB
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6HSU
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6HS9
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6HSQ
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6HSA
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6HS8
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1HRP
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6SMF
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6SME
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2SHK
 | | THE THREE-DIMENSIONAL STRUCTURE OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI COMPLEXED WITH ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SHIKIMATE KINASE | | 著者 | Krell, T, Coggins, J.R, Lapthorn, A.J. | | 登録日 | 1997-10-27 | | 公開日 | 1998-11-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of shikimate kinase from Erwinia chrysanthemi.
Acta Crystallogr.,Sect.D, 53, 1997
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1V1J
 | | Crystal structure of type II Dehydroquintae Dehydratase from Streptomyces coelicolor in complex with 3-fluoro | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-ANHYDRO-3-FLUORO-QUINIC ACID, 3-DEHYDROQUINATE DEHYDRATASE | | 著者 | Roszak, A.W, Coggins, J.R, Lapthorn, A.J. | | 登録日 | 2004-04-16 | | 公開日 | 2005-01-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | (1R,4S,5R)-3-Fluoro-1,4,5-Trihydroxy-2-Cyclohexene-1-Carboxylic Acid: The Fluoro Analogue of the Enolate Intermediate in the Reaction Catalyzed by Type II Dehydroquinases
Org.Biomol.Chem., 2, 2004
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1SHK
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2BT4
 | | Type II Dehydroquinase inhibitor complex | | 分子名称: | (1S,3R,4R,5S)-1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)CYCLOHEXANECARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-DEHYDROQUINATE DEHYDRATASE, ... | | 著者 | Toscano, M.D, Stewart, K.A, Coggins, J.R, Lapthorn, A.J, Abell, C. | | 登録日 | 2005-05-26 | | 公開日 | 2006-02-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Rational Design of New Bifunctional Inhibitors of Type II Dehydroquinase.
Org.Biomol.Chem., 3, 2005
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5EL8
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5ELA
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5ELG
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1E6C
 | | K15M MUTANT OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | | 著者 | Maclean, J, Krell, T, Coggins, J.R, Lapthorn, A.J. | | 登録日 | 2000-08-10 | | 公開日 | 2001-06-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Biochemical and X-Ray Crystallographic Studies on Shikimate Kinase: The Important Structural Role of the P-Loop Lysine
Protein Sci., 10, 2001
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2VD3
 | | The structure of histidine inhibited HisG from Methanobacterium thermoautotrophicum | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ATP PHOSPHORIBOSYLTRANSFERASE, ... | | 著者 | Lohkamp, B, Schweikert, T, Lapthorn, A.J. | | 登録日 | 2007-09-28 | | 公開日 | 2008-11-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The Structure of Histidine Inhibited Hisg from Methanobacterium Thermoautotrophicum
To be Published
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2VD2
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1NYT
 | | SHIKIMATE DEHYDROGENASE AroE COMPLEXED WITH NADP+ | | 分子名称: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... | | 著者 | Roszak, A.W, Lapthorn, A.J. | | 登録日 | 2003-02-13 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities.
J.Biol.Chem., 278, 2003
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1OYJ
 | | Crystal structure solution of Rice GST1 (OsGSTU1) in complex with glutathione. | | 分子名称: | CHLORIDE ION, GLUTATHIONE, GLYCEROL, ... | | 著者 | Dixon, D.P, McEwen, A.G, Lapthorn, A.J, Edwards, R. | | 登録日 | 2003-04-04 | | 公開日 | 2003-07-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Forced evolution of a herbicide detoxifying glutathione transferase.
J.Biol.Chem., 278, 2003
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2XD9
 | | STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-4,6,7-Trihydroxy-2-((E)-prop-1- enyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid | | 分子名称: | (4R,6R,7S)-4,6,7-TRIHYDROXY-2-[(1E)-PROP-1-EN-1-YL]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC ACID, 3-DEHYDROQUINATE DEHYDRATASE | | 著者 | Paz, S, Tizon, L, Otero, J.M, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J, Lamb, H, Hawkins, A.R, Lapthorn, A.J, Castedo, L, Gonzalez-Bello, C. | | 登録日 | 2010-04-30 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase.
ChemMedChem, 6, 2011
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1Q1K
 | | Structure of ATP-phosphoribosyltransferase from E. coli complexed with PR-ATP | | 分子名称: | ATP phosphoribosyltransferase, L(+)-TARTARIC ACID, PHOSPHORIBOSYL ATP | | 著者 | Lohkamp, B, McDermott, G, Coggins, J.R, Lapthorn, A.J. | | 登録日 | 2003-07-21 | | 公開日 | 2004-03-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The structure of Escherichia coli ATP-phosphoribosyltransferase: identification of substrate binding sites and mode of AMP inhibition
J.Mol.Biol., 336, 2004
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1GU0
 | | CRYSTAL STRUCTURE OF TYPE II DEHYDROQUINASE FROM STREPTOMYCES COELICOLOR | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-DEHYDROQUINATE DEHYDRATASE | | 著者 | Roszak, A.W, Krell, T, Robinson, D, Hunter, I.S, Coggins, J.R, Lapthorn, A.J. | | 登録日 | 2002-01-22 | | 公開日 | 2002-04-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structure and Mechanism of the Type II Dehydroquinase from Streptomyces Coelicolor
Structure, 10, 2002
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