6GQ3
 
 | | Human asparagine synthetase (ASNS) in complex with 6-diazo-5-oxo-L-norleucine (DON) at 1.85 A resolution | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-OXO-L-NORLEUCINE, ... | | 著者 | Zhu, W, Radadiya, A, Bisson, C, Jin, Y, Nordin, B.E, Imasaki, T, Wenzel, S, Sedelnikova, S.E, Berry, A.H, Nomanbhoy, T.K, Kozarich, J.W, Takagi, Y, Rice, D.W, Richards, N.G.J. | | 登録日 | 2018-06-07 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Commun Biol, 2, 2019
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1QHM
 | | ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN | | 分子名称: | PYRUVATE FORMATE-LYASE | | 著者 | Leppanen, V.-M, Merckel, M.C, Ollis, D.L, Wong, K.K, Kozarich, J.W, Goldman, A. | | 登録日 | 1999-05-19 | | 公開日 | 2000-05-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase.
Structure Fold.Des., 7, 1999
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1JOF
 | | Neurospora crassa 3-carboxy-cis,cis-mucoante lactonizing enzyme | | 分子名称: | BETA-MERCAPTOETHANOL, CARBOXY-CIS,CIS-MUCONATE CYCLASE, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ... | | 著者 | Kajander, T, Merckel, M.C, Thompson, A, Deacon, A.M, Mazur, P, Kozarich, J.W, Goldman, A. | | 登録日 | 2001-07-28 | | 公開日 | 2002-04-12 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of Neurospora crassa 3-carboxy-cis,cis-muconate lactonizing enzyme, a beta propeller cycloisomerase.
Structure, 10, 2002
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1MDR
 | | THE ROLE OF LYSINE 166 IN THE MECHANISM OF MANDELATE RACEMASE FROM PSEUDOMONAS PUTIDA: MECHANISTIC AND CRYSTALLOGRAPHIC EVIDENCE FOR STEREOSPECIFIC ALKYLATION BY (R)-ALPHA-PHENYLGLYCIDATE | | 分子名称: | ATROLACTIC ACID (2-PHENYL-LACTIC ACID), MAGNESIUM ION, MANDELATE RACEMASE | | 著者 | Landro, J.A, Gerlt, J.A, Kozarich, J.W, Koo, C.W, Shah, V.J, Kenyon, G.L, Neidhart, D.J, Fujita, S, Petsko, G.A. | | 登録日 | 1993-11-19 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The role of lysine 166 in the mechanism of mandelate racemase from Pseudomonas putida: mechanistic and crystallographic evidence for stereospecific alkylation by (R)-alpha-phenylglycidate.
Biochemistry, 33, 1994
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1MNS
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1MZO
 | | Crystal structure of pyruvate formate-lyase with pyruvate | | 分子名称: | PYRUVIC ACID, Pyruvate formate-lyase, TRIETHYLENE GLYCOL | | 著者 | Lehtio, L, Leppanen, V.-M, Kozarich, J.W, Goldman, A. | | 登録日 | 2002-10-09 | | 公開日 | 2002-12-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of Escherichia coli pyruvate formate-lyase with pyruvate.
Acta Crystallogr.,Sect.D, 58, 2002
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1RE5
 | | Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-carboxy-cis,cis-muconate cycloisomerase, CITRIC ACID | | 著者 | Yang, J, Wang, Y, Woolridge, E.M, Petsko, G.A, Kozarich, J.W, Ringe, D. | | 登録日 | 2003-11-06 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of 3-Carboxy-cis,cis-muconate Lactonizing Enzyme from Pseudomonas putida, a Fumarase Class II Type Cycloisomerase: Enzyme Evolution in Parallel Pathways.
Biochemistry, 43, 2004
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1MRA
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1A8T
 | | METALLO-BETA-LACTAMASE IN COMPLEX WITH L-159,061 | | 分子名称: | 2-BUTYL-6-HYDROXY-3-[2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-3H-QUINAZOLIN-4-ONE, METALLO-BETA-LACTAMASE, ZINC ION | | 著者 | Fitzgerald, P.M.D, Toney, J.H, Grover, N, Vanderwall, D. | | 登録日 | 1998-03-23 | | 公開日 | 1998-10-14 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Antibiotic sensitization using biphenyl tetrazoles as potent inhibitors of Bacteroides fragilis metallo-beta-lactamase.
Chem.Biol., 5, 1998
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1MDL
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4L7F
 | | Co-crystal Structure of JNK1 and AX13587 | | 分子名称: | Mitogen-activated protein kinase 8, N-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide | | 著者 | Walter, R.L, Ranieri, G.M, Riggs, A.M, Weissig, H, Li, B, Shreder, K.R. | | 登録日 | 2013-06-13 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
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1DTN
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