1YPA
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1ZT4
| The crystal structure of human CD1d with and without alpha-Galactosylceramide | Descriptor: | Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE, T-cell surface glycoprotein CD1d | Authors: | Koch, M, Stronge, V.S, Shepherd, D, Gadola, S.D, Mathew, B, Ritter, G, Fersht, A.R, Besra, G.S, Schmidt, R.R, Jones, E.Y, Cerundolo, V, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-05-26 | Release date: | 2005-07-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of human CD1d with and without alpha-galactosylceramide Nat.Immunol., 6, 2005
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1ZTR
| Solution structure of Engrailed homeodomain L16A mutant | Descriptor: | Segmentation polarity homeobox protein engrailed | Authors: | Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R. | Deposit date: | 2005-05-27 | Release date: | 2005-10-18 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Solution structure of a protein denatured state and folding intermediate. Nature, 437, 2005
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1BRS
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1CIR
| COMPLEX OF TWO FRAGMENTS OF CI2 [(1-40)(DOT)(41-64)] | Descriptor: | CHYMOTRYPSIN INHIBITOR 2 | Authors: | Davis, B.J, Fersht, A.R. | Deposit date: | 1995-10-02 | Release date: | 1996-01-29 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996
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1CIQ
| COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64 | Descriptor: | CHYMOTRYPSIN INHIBITOR 2 | Authors: | Buckle, A.M, Fersht, A.R. | Deposit date: | 1995-10-02 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996
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5AOJ
| Structure of the p53 cancer mutant Y220C in complex with 2-hydroxy-3, 5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid | Descriptor: | 2-hydroxy-3,5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ... | Authors: | Joerger, A.C, Baud, M.G, Bauer, M.R, Fersht, A.R. | Deposit date: | 2015-09-10 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53. Structure, 23, 2015
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1P7I
| CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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1P7J
| Crystal structure of engrailed homeodomain mutant K52E | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
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1QPU
| SOLUTION STRUCTURE OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562 | Descriptor: | CYTOCHROME B562, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Arnesano, F, Banci, L, Bertini, I, Faraone-Mennella, J, Rosato, A, Barker, P.D, Fersht, A.R. | Deposit date: | 1999-05-30 | Release date: | 1999-06-02 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry, 38, 1999
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1SS1
| STAPHYLOCOCCAL PROTEIN A, B-DOMAIN, Y15W MUTANT, NMR, 25 STRUCTURES | Descriptor: | Immunoglobulin G binding protein A | Authors: | Sato, S, Religa, T.L, Daggett, V, Fersht, A.R. | Deposit date: | 2004-03-23 | Release date: | 2004-04-06 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | From The Cover: Testing protein-folding simulations by experiment: B domain of protein A. Proc.Natl.Acad.Sci.USA, 101, 2004
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2KZG
| A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution | Descriptor: | Pre-mRNA-processing factor 40 homolog A | Authors: | Korzhnev, D.M, Religa, T.L, Banachewicz, W, Fersht, A.R, Kay, L.E. | Deposit date: | 2010-06-17 | Release date: | 2010-09-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A transient and low-populated protein-folding intermediate at atomic resolution. Science, 329, 2010
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2L9V
| NMR structure of the FF domain L24A mutant's folding transition state | Descriptor: | Pre-mRNA-processing factor 40 homolog A | Authors: | Korzhnev, D.M, Vernon, R.M, Religa, T.L, Hansen, A, Baker, D, Fersht, A.R, Kay, L.E. | Deposit date: | 2011-02-24 | Release date: | 2011-09-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study. J.Am.Chem.Soc., 133, 2011
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2NNT
| General structural motifs of amyloid protofilaments | Descriptor: | Transcription elongation regulator 1 | Authors: | Ferguson, N, Becker, J, Tidow, H, Tremmel, S, Sharpe, T.D, Krause, G, Flinders, J, Petrovich, M, Berriman, J, Oschkinat, H, Fersht, A.R. | Deposit date: | 2006-10-24 | Release date: | 2006-11-14 | Last modified: | 2023-12-27 | Method: | SOLID-STATE NMR | Cite: | General structural motifs of amyloid protofilaments. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2UWQ
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2VY5
| U11-48K CHHC Zn-finger protein domain | Descriptor: | U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION | Authors: | Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R. | Deposit date: | 2008-07-18 | Release date: | 2009-02-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure, 17, 2009
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2VYR
| Structure of human MDM4 N-terminal domain bound to a single domain antibody | Descriptor: | HUMAN SINGLE DOMAIN ANTIBODY, MDM4 PROTEIN, SULFATE ION | Authors: | Yu, G.W, Vaysburd, M, Allen, M.D, Settanni, G, Fersht, A.R. | Deposit date: | 2008-07-28 | Release date: | 2008-11-25 | Last modified: | 2013-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Human Mdm4 N-Terminal Domain Bound to a Single-Domain Antibody. J.Mol.Biol., 385, 2009
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2VY4
| U11-48K CHHC ZN-FINGER DOMAIN | Descriptor: | U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION | Authors: | Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R. | Deposit date: | 2008-07-17 | Release date: | 2009-02-17 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure, 17, 2009
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1BAN
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1BAO
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1BSE
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1BSA
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1BSD
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1BRG
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1BSB
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