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DIRECT OBSERVATION OF BETTER HYDRATION AT THE N-TERMINUS OF AN ALPHA-HELIX WITH GLYCINE RATHER THAN ALANINE AS N-CAP
分子名称:	CHYMOTRYPSIN INHIBITOR 2
著者	Harpaz, Y, Elmasry, N, Fersht, A.R, Henrick, K.
登録日	1993-01-10
公開日	1994-01-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Direct observation of better hydration at the N terminus of an alpha-helix with glycine rather than alanine as the N-cap residue. Proc.Natl.Acad.Sci.USA, 91, 1994

1ZT4

The crystal structure of human CD1d with and without alpha-Galactosylceramide
分子名称:	Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE, T-cell surface glycoprotein CD1d
著者	Koch, M, Stronge, V.S, Shepherd, D, Gadola, S.D, Mathew, B, Ritter, G, Fersht, A.R, Besra, G.S, Schmidt, R.R, Jones, E.Y, Cerundolo, V, Structural Proteomics in Europe (SPINE)
登録日	2005-05-26
公開日	2005-07-19
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	The crystal structure of human CD1d with and without alpha-galactosylceramide Nat.Immunol., 6, 2005

1ZTR

Solution structure of Engrailed homeodomain L16A mutant
分子名称:	Segmentation polarity homeobox protein engrailed
著者	Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R.
登録日	2005-05-27
公開日	2005-10-18
最終更新日	2021-11-10
実験手法	SOLUTION NMR
主引用文献	Solution structure of a protein denatured state and folding intermediate. Nature, 437, 2005

1BRS

PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION
分子名称:	BARNASE, BARSTAR
著者	Buckle, A.M, Schreiber, G, Fersht, A.R.
登録日	1994-03-11
公開日	1994-06-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution. Biochemistry, 33, 1994

1CIR

COMPLEX OF TWO FRAGMENTS OF CI2 [(1-40)(DOT)(41-64)]
分子名称:	CHYMOTRYPSIN INHIBITOR 2
著者	Davis, B.J, Fersht, A.R.
登録日	1995-10-02
公開日	1996-01-29
最終更新日	2022-02-16
実験手法	SOLUTION NMR
主引用文献	Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996

1CIQ

COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64
分子名称:	CHYMOTRYPSIN INHIBITOR 2
著者	Buckle, A.M, Fersht, A.R.
登録日	1995-10-02
公開日	1996-03-08
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996

5AOJ

Structure of the p53 cancer mutant Y220C in complex with 2-hydroxy-3, 5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid
分子名称:	2-hydroxy-3,5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ...
著者	Joerger, A.C, Baud, M.G, Bauer, M.R, Fersht, A.R.
登録日	2015-09-10
公開日	2015-12-16
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.47 Å)
主引用文献	Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53. Structure, 23, 2015

1P7I

CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A
分子名称:	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed
著者	Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F.
登録日	2003-05-02
公開日	2003-10-14
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003

1P7J

Crystal structure of engrailed homeodomain mutant K52E
分子名称:	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed
著者	Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F.
登録日	2003-05-02
公開日	2003-10-14
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003

1QPU

SOLUTION STRUCTURE OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562
分子名称:	CYTOCHROME B562, PROTOPORPHYRIN IX CONTAINING FE
著者	Arnesano, F, Banci, L, Bertini, I, Faraone-Mennella, J, Rosato, A, Barker, P.D, Fersht, A.R.
登録日	1999-05-30
公開日	1999-06-02
最終更新日	2022-03-02
実験手法	SOLUTION NMR
主引用文献	The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry, 38, 1999

1SS1

STAPHYLOCOCCAL PROTEIN A, B-DOMAIN, Y15W MUTANT, NMR, 25 STRUCTURES
分子名称:	Immunoglobulin G binding protein A
著者	Sato, S, Religa, T.L, Daggett, V, Fersht, A.R.
登録日	2004-03-23
公開日	2004-04-06
最終更新日	2021-10-27
実験手法	SOLUTION NMR
主引用文献	From The Cover: Testing protein-folding simulations by experiment: B domain of protein A. Proc.Natl.Acad.Sci.USA, 101, 2004

2KZG

A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution
分子名称:	Pre-mRNA-processing factor 40 homolog A
著者	Korzhnev, D.M, Religa, T.L, Banachewicz, W, Fersht, A.R, Kay, L.E.
登録日	2010-06-17
公開日	2010-09-29
最終更新日	2024-05-01
実験手法	SOLUTION NMR
主引用文献	A transient and low-populated protein-folding intermediate at atomic resolution. Science, 329, 2010

2L9V

NMR structure of the FF domain L24A mutant's folding transition state
分子名称:	Pre-mRNA-processing factor 40 homolog A
著者	Korzhnev, D.M, Vernon, R.M, Religa, T.L, Hansen, A, Baker, D, Fersht, A.R, Kay, L.E.
登録日	2011-02-24
公開日	2011-09-28
最終更新日	2024-05-01
実験手法	SOLUTION NMR
主引用文献	Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study. J.Am.Chem.Soc., 133, 2011

2NNT

General structural motifs of amyloid protofilaments
分子名称:	Transcription elongation regulator 1
著者	Ferguson, N, Becker, J, Tidow, H, Tremmel, S, Sharpe, T.D, Krause, G, Flinders, J, Petrovich, M, Berriman, J, Oschkinat, H, Fersht, A.R.
登録日	2006-10-24
公開日	2006-11-14
最終更新日	2023-12-27
実験手法	SOLID-STATE NMR
主引用文献	General structural motifs of amyloid protofilaments. Proc.Natl.Acad.Sci.Usa, 103, 2006

2UWQ

Solution structure of ASPP2 N-terminus
分子名称:	APOPTOSIS-STIMULATING OF P53 PROTEIN 2
著者	Tidow, H, Rutherford, T.J, Andreeva, A, Fersht, A.R.
登録日	2007-03-22
公開日	2007-07-10
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold. J. Mol. Biol., 371, 2007

2VY5

U11-48K CHHC Zn-finger protein domain
分子名称:	U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
著者	Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
登録日	2008-07-18
公開日	2009-02-17
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure, 17, 2009

2VYR

Structure of human MDM4 N-terminal domain bound to a single domain antibody
分子名称:	HUMAN SINGLE DOMAIN ANTIBODY, MDM4 PROTEIN, SULFATE ION
著者	Yu, G.W, Vaysburd, M, Allen, M.D, Settanni, G, Fersht, A.R.
登録日	2008-07-28
公開日	2008-11-25
最終更新日	2013-03-06
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structure of Human Mdm4 N-Terminal Domain Bound to a Single-Domain Antibody. J.Mol.Biol., 385, 2009

2VY4

U11-48K CHHC ZN-FINGER DOMAIN
分子名称:	U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN, ZINC ION
著者	Tidow, H, Andreeva, A, Rutherford, T.J, Fersht, A.R.
登録日	2008-07-17
公開日	2009-02-17
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns. Structure, 17, 2009

1BAN

THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS
分子名称:	BARNASE
著者	Chen, Y.W, Fersht, A.R, Henrick, K.
登録日	1993-05-19
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants. J.Mol.Biol., 234, 1993

1BAO

THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS
分子名称:	BARNASE, ZINC ION
著者	Chen, Y.W, Fersht, A.R, Henrick, K.
登録日	1993-05-19
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants. J.Mol.Biol., 234, 1993

1BSE

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BSA

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BSD

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

1BRG

CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE
分子名称:	BARNASE, ZINC ION
著者	Chen, Y.W, Fersht, A.R, Henrick, K.
登録日	1994-03-30
公開日	1994-06-22
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Crystallographic analysis of Phe-->Leu substitution in the hydrophobic core of barnase. Acta Crystallogr.,Sect.D, 51, 1995

1BSB

CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
分子名称:	BARNASE
著者	Buckle, A.M, Henrick, K, Fersht, A.R.
登録日	1993-07-19
公開日	1994-01-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structural analysis of mutations in the hydrophobic cores of barnase. J.Mol.Biol., 234, 1993

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