1ULA
 
 | | APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | | 分子名称: | PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | | 著者 | Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E. | | 登録日 | 1991-11-05 | | 公開日 | 1993-01-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
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1ULB
 | | APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | | 分子名称: | GUANINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | | 著者 | Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E. | | 登録日 | 1991-11-05 | | 公開日 | 1993-01-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
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1HIG
 | | THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA. | | 分子名称: | INTERFERON-GAMMA | | 著者 | Ealick, S.E, Cook, W.J, Vijay-Kumar, S, Carson, M, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E. | | 登録日 | 1991-10-03 | | 公開日 | 1992-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Three-dimensional structure of recombinant human interferon-gamma.
Science, 252, 1991
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2HS0
 | | T. maritima PurL complexed with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase II | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-07-20 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006
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2HRY
 | | T. maritima PurL complexed with AMPPCP | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-07-20 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006
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2HS4
 | | T. maritima PurL complexed with FGAR and AMPPCP | | 分子名称: | MAGNESIUM ION, N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, ... | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-07-21 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006
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2HS3
 | | T. maritima PurL complexed with FGAR | | 分子名称: | N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, Phosphoribosylformylglycinamidine synthase II | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-07-21 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006
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2HRU
 | | T. maritima PurL complexed with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase II | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-07-20 | | 公開日 | 2007-01-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006
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5HFT
 | | Crystal structure of HpxW | | 分子名称: | Gamma-glutamyltranspeptidase | | 著者 | Ealick, S.E, Hicks, K.A. | | 登録日 | 2016-01-07 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.646 Å) | | 主引用文献 | Biochemical and structural characterization of Klebsiella pneumoniae oxamate amidohydrolase in the uric acid degradation pathway.
Acta Crystallogr D Struct Biol, 72, 2016
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1ZUD
 | | Structure of ThiS-ThiF protein complex | | 分子名称: | Adenylyltransferase thiF, CALCIUM ION, SODIUM ION, ... | | 著者 | Ealick, S.E, Lehmann, C. | | 登録日 | 2005-05-30 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structure of the Escherichia coli ThiS-ThiF Complex, a Key Component of the Sulfur Transfer System in Thiamin Biosynthesis.
Biochemistry, 45, 2006
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3D54
 | | Structure of PurLQS from Thermotoga maritima | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Formylglycinamide ribonucleotide amidotransferase, Phosphoribosylformylglycinamidine synthase 1, ... | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2008-05-15 | | 公開日 | 2008-07-22 | | 最終更新日 | 2017-02-01 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation.
Biochemistry, 47, 2008
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1T3T
 | | Structure of Formylglycinamide synthetase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ... | | 著者 | Ealick, S.E, Anand, R, Hoskin, A.A, Stubbe, J. | | 登録日 | 2004-04-27 | | 公開日 | 2004-09-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray crystallography
Biochemistry, 43, 2004
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2NSJ
 | | E. coli PurE H45Q mutant complexed with CAIR | | 分子名称: | 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-11-04 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
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2NSL
 | | E. coli PurE H45N mutant complexed with CAIR | | 分子名称: | 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-11-04 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
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2NSH
 | | E. coli PurE H45Q mutant complexed with nitro-AIR | | 分子名称: | ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE, Phosphoribosylaminoimidazole carboxylase catalytic subunit | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2006-11-04 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
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2QJI
 | | M. jannaschii ADH synthase complexed with dihydroxyacetone phosphate and glycerol | | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, GLYCEROL, Putative aldolase MJ0400 | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2007-07-07 | | 公開日 | 2007-10-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Biochemistry, 46, 2007
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2QQD
 | | N47A mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, AGMATINE, PYRUVIC ACID, ... | | 著者 | Ealick, S.E, Soriano, E.S. | | 登録日 | 2007-07-26 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
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2QRO
 | | Human Deoxycytidine kinase dAMP, UDP, Mg ion product complex | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | | 著者 | Ealick, S.E, Soriano, E.V. | | 登録日 | 2007-07-28 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Structures of human deoxycytidine kinase product complexes.
Acta Crystallogr.,Sect.D, 63, 2007
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2QQC
 | | E109Q mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, AGMATINE, Pyruvoyl-dependent arginine decarboxylase subunit alpha, ... | | 著者 | Ealick, S.E, Soriano, E.S. | | 登録日 | 2007-07-26 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
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2QRN
 | | Human Deoxycytidine kinase dCMP, UDP, Mg ion product complex | | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | | 著者 | Ealick, S.E, Soriano, E.V. | | 登録日 | 2007-07-28 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structures of human deoxycytidine kinase product complexes.
Acta Crystallogr.,Sect.D, 63, 2007
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2QJG
 | | M. jannaschii ADH synthase complexed with F1,6P | | 分子名称: | 1,6-DI-O-PHOSPHONO-D-ALLITOL, Putative aldolase MJ0400 | | 著者 | Ealick, S.E, Morar, M. | | 登録日 | 2007-07-07 | | 公開日 | 2007-10-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Biochemistry, 46, 2007
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2QRY
 | | Periplasmic thiamin binding protein | | 分子名称: | THIAMIN PHOSPHATE, Thiamine-binding periplasmic protein | | 著者 | Ealick, S.E, Soriano, E.V. | | 登録日 | 2007-07-30 | | 公開日 | 2008-02-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor
Biochemistry, 47, 2008
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2QJH
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1OV6
 | | M64V PNP + ALLO | | 分子名称: | 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | | 著者 | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | | 登録日 | 2003-03-25 | | 公開日 | 2004-02-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
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1OVG
 | | M64V PNP +MePdr | | 分子名称: | 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase | | 著者 | Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J. | | 登録日 | 2003-03-26 | | 公開日 | 2004-02-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
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