5OYG
| Structure of calcium-free mTMEM16A chloride channel at 4.06 A resolution | Descriptor: | Anoctamin-1 | Authors: | Paulino, C, Kalienkova, V, Lam, K.M, Neldner, Y, Dutzler, R. | Deposit date: | 2017-09-08 | Release date: | 2017-12-20 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM. Nature, 552, 2017
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5HEJ
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5HEW
| Pentameric ligand-gated ion channel ELIC mutant T28D | Descriptor: | Gamma-aminobutyric-acid receptor subunit beta-1 | Authors: | Engeler, S, Dutzler, R. | Deposit date: | 2016-01-06 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels. Plos Biol., 14, 2016
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5HEO
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5HEU
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5HEH
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2HT3
| Structure of the Escherichia coli ClC chloride channel Y445L mutant and Fab complex | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | Deposit date: | 2006-07-25 | Release date: | 2006-09-19 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger J.Mol.Biol., 362, 2006
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2HT4
| Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | Deposit date: | 2006-07-25 | Release date: | 2006-09-19 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006
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2HTL
| Structure of the Escherichia coli ClC chloride channel Y445F mutant and Fab complex | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | Deposit date: | 2006-07-26 | Release date: | 2006-09-19 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006
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2HTK
| Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex | Descriptor: | BROMIDE ION, Fab fragment, Heavy chain, ... | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | Deposit date: | 2006-07-26 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | Synergism between halide binding and proton transport in a CLC-type exchanger J.Mol.Biol., 362, 2006
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2J9L
| Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5, CHLORIDE ION | Authors: | Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R. | Deposit date: | 2006-11-13 | Release date: | 2007-01-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5 Nat.Struct.Mol.Biol., 14, 2006
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2JA3
| Cytoplasmic Domain of the Human Chloride Transporter ClC-5 in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE CHANNEL PROTEIN 5 | Authors: | Meyer, S, Savaresi, S, Forster, I.C, Dutzler, R. | Deposit date: | 2006-11-21 | Release date: | 2007-01-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Nucleotide Recognition by the Cytoplasmic Domain of the Human Chloride Transporter Clc-5 Nat.Struct.Mol.Biol., 14, 2006
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2EXW
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2EXY
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2EZ0
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2HT2
| Structure of the Escherichia coli ClC chloride channel Y445H mutant and Fab complex | Descriptor: | BROMIDE ION, Fab fragment, heavy chain, ... | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | Deposit date: | 2006-07-25 | Release date: | 2006-09-19 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger. J.Mol.Biol., 362, 2006
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2HLF
| Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex | Descriptor: | BROMIDE ION, Fab Fragment, Heavy chain, ... | Authors: | Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R. | Deposit date: | 2006-07-07 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Synergism Between Halide Binding and Proton Transport in a CLC-type Exchanger J.Mol.Biol., 362, 2006
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7P16
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7P14
| Structure of full-length rXKR9 in complex with a sybody at 3.66A | Descriptor: | DIUNDECYL PHOSPHATIDYL CHOLINE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sybody, ... | Authors: | Straub, M.S, Sawicka, M, Dutzler, R. | Deposit date: | 2021-07-01 | Release date: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Cryo-EM structures of the caspase activated protein XKR9 involved in apoptotic lipid scrambling. Elife, 10, 2021
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7P5M
| Cryo-EM structure of human TTYH2 in lipid nanodiscs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 2 | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | Deposit date: | 2021-07-14 | Release date: | 2021-08-11 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. Nat Commun, 12, 2021
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7P5C
| Cryo-EM structure of human TTYH3 in Ca2+ and GDN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 3 | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | Deposit date: | 2021-07-14 | Release date: | 2021-08-11 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. Nat Commun, 12, 2021
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7P54
| Cryo-EM structure of human TTYH2 in GDN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 2 | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | Deposit date: | 2021-07-14 | Release date: | 2021-08-11 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. Nat Commun, 12, 2021
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7P5J
| Cryo-EM structure of human TTYH1 in GDN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein tweety homolog 1 | Authors: | Sukalskaia, A, Straub, M.S, Sawicka, M, Deneka, D, Dutzler, R. | Deposit date: | 2021-07-14 | Release date: | 2021-08-11 | Last modified: | 2021-09-08 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions. Nat Commun, 12, 2021
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6QMB
| Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (closed state) | Descriptor: | CALCIUM ION, Predicted protein | Authors: | Kalienkova, V, Clerico Mosina, V, Bryner, L, Oostergetel, G.T, Dutzler, R, Paulino, C. | Deposit date: | 2019-02-01 | Release date: | 2019-03-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM. Elife, 8, 2019
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6QPB
| Cryo-EM structure of calcium-free mTMEM16F lipid scramblase in digitonin | Descriptor: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6 | Authors: | Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C. | Deposit date: | 2019-02-13 | Release date: | 2019-03-06 | Last modified: | 2019-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F. Elife, 8, 2019
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